HDL clearance

Stable Identifier
R-HSA-8964011
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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HDL clearance
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Clearance of circulating HDL particles involves particle binding to cell-surface SR-BI receptors, particle disassembly with rlease of pre-beta HDL (Silver & Tall 2001), and uptake of the latter mediated by cell-surface CUBN:AMN complex (Kozyraki et al. 1999).
Literature References
PubMed ID Title Journal Year
10371504 The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein

Fyfe, JC, Krahe, R, Kozyraki, R, Kristiansen, M, Moestrup, SK, Aminoff, M, de la Chapelle, A, Jacobsen, C, Verroust, PJ, Cui, S, Christensen, EI, Gerdes, C

Nat Med 1999
11561168 The cellular biology of scavenger receptor class B type I

Tall, AR, Silver, DL

Curr Opin Lipidol 2001
Participants
Events
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as an event of
Event Information
Go Biological Process
high-density lipoprotein particle clearance (0034384)
Orthologous Events
HDL clearance (Bos taurus)
HDL clearance (Canis familiaris)
HDL clearance (Gallus gallus)
HDL clearance (Mus musculus)
HDL clearance (Rattus norvegicus)
HDL clearance (Sus scrofa)
Cross References
BioModels Database
Authored
D'Eustachio, P  (2008-05-12)
Reviewed
Jassal, B  (2016-02-18)
Created
D'Eustachio, P  (2017-02-15)
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