HDL clearance

Stable Identifier
R-HSA-8964011
Type
Pathway
Species
Homo sapiens
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Clearance of circulating HDL particles involves particle binding to cell-surface SR-BI receptors, particle disassembly with rlease of pre-beta HDL (Silver & Tall 2001), and uptake of the latter mediated by cell-surface CUBN:AMN complex (Kozyraki et al. 1999).

Literature References
PubMed ID Title Journal Year
10371504 The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein

Fyfe, JC, Krahe, R, Kozyraki, R, Kristiansen, M, Moestrup, SK, Aminoff, M, de la Chapelle, A, Jacobsen, C, Verroust, PJ, Cui, S, Christensen, EI, Gerdes, C

Nat Med 1999
11561168 The cellular biology of scavenger receptor class B type I

Tall, AR, Silver, DL

Curr Opin Lipidol 2001
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Orthologous Events
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GlyCosmos
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