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HDLBP binds HDL
Stable Identifier
R-HSA-8858252
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
,
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein clearance (Homo sapiens)
HDL clearance (Homo sapiens)
HDLBP binds HDL (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
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PDF
SVG
|
PNG
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High
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PPTX
|
SBGN
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Vigilin (HDL-binding protein, HDLBP) predominantly resides on most human cell membranes and binds high-density lipoproteins (HDLs). Although its role remains unclear, Vigilin may mediate removal of excess intracellular cholesterol (Bocharov et al. 2001).
Literature References
PubMed ID
Title
Journal
Year
11284697
Characterization of a 95 kDa high affinity human high density lipoprotein-binding protein
Baranova, IN
,
Patterson, AP
,
Eggerman, TL
,
Bocharov, AV
,
Vishnyakova, TG
Biochemistry
2001
Participants
Input
HDLBP [plasma membrane]
(Homo sapiens)
spherical HDL [extracellular region]
(Homo sapiens)
Output
HDLBP:HDL [plasma membrane]
(Homo sapiens)
Participates
as an event of
HDL clearance (Homo sapiens)
Orthologous Events
HDLBP binds HDL (Bos taurus)
HDLBP binds HDL (Canis familiaris)
HDLBP binds HDL (Gallus gallus)
HDLBP binds HDL (Mus musculus)
HDLBP binds HDL (Rattus norvegicus)
HDLBP binds HDL (Sus scrofa)
Authored
Jassal, B (2016-02-18)
Reviewed
D'Eustachio, P (2016-04-05)
Created
Jassal, B (2016-02-18)
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