Reactome | ALOXE3 [cytosol]

ALOXE3 [cytosol]

Stable Identifier

R-HSA-8942204

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Hydroperoxide isomerase ALOXE3 ecNumber evidence="4 7 10 11 12"5.4.4.7/ecNumber, LOXE3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BYJ1 ALOXE3

Gene Names

ALOXE3

Chain

chain:1-711

Reference Genes

BioGPS Gene:59344 ALOXE3

COSMIC (genes):ALOXE3 ALOXE3

CTD Gene:59344 ALOXE3

dbSNP Gene:59344 ALOXE3

ENSEMBL:ENSG00000179148 ALOXE3

HGNC:13743 ALOXE3

Monarch:59344 ALOXE3

NCBI Gene:59344 ALOXE3

OMIM:607206 ALOXE3

UCSC:Q9BYJ1 ALOXE3

Reference Transcript

Other Identifiers

11732766_a_at

11732767_at

11747613_a_at

11747614_a_at

16840817

207708_PM_at

207708_at

222383_3p_s_at

222383_PM_s_at

222383_s_at

3744095

3744096

3744097

3744098

3744099

3744100

3744101

3744102

3744104

3744105

3744106

3744108

3744109

3744110

3744111

3744112

3744113

3744114

3744116

3744117

3744118

3744119

3744120

3744121

3744123

3744124

59344

8012326

A_24_P347880

GE62901

GO:0001676

GO:0003824

GO:0005506

GO:0005515

GO:0005737

GO:0005829

GO:0006629

GO:0006631

GO:0006665

GO:0006690

GO:0016491

GO:0016702

GO:0016829

GO:0016853

GO:0019233

GO:0019369

GO:0019372

GO:0030154

GO:0034440

GO:0035357

GO:0043651

GO:0045444

GO:0046513

GO:0046872

GO:0048856

GO:0050486

GO:0050877

GO:0051120

GO:0051122

GO:0051213

GO:0061436

GO:0106255

GO:0106256

HMNXSV003051322

Hs.314067.0.A1_3p_at

Hs.314067.0.A1_3p_s_at

Hs.314067.0.A1_3p_x_at

ILMN_1678255

PH_hs_0012753

TC17001101.hg

g11055995_3p_at

Inferred To

Homologues of ALOXE3 [cytosol] (Dictyostelium discoideum)

Homologues of ALOXE3 [cytosol] (Xenopus tropicalis)

lipA [cytosol] (Dictyostelium discoideum)

ALOXE3 [cytosol] (Bos taurus)

ALOXE3 [cytosol] (Canis familiaris)

ALOXE3 [cytosol] (Danio rerio)

ALOXE3 [cytosol] (Dictyostelium discoideum)

ALOXE3 [cytosol] (Gallus gallus)

ALOXE3 [cytosol] (Mus musculus)

ALOXE3 [cytosol] (Rattus norvegicus)

ALOXE3 [cytosol] (Sus scrofa)

ALOXE3 [cytosol] (Xenopus tropicalis)

Cross References

Guide to Pharmacology - Targets

1390

ENSEMBL

ENSP00000369494, ENSP00000314879, ENST00000380149, ENST00000448843, ENST00000318227, ENSP00000400581

OpenTargets

ENSG00000179148

IntEnz

4.2.1.152

HPA

ENSG00000179148-ALOXE3

PRO

Q9BYJ1

Pharos - Targets

Q9BYJ1

Orphanet

ALOXE3

HMDB Protein

HMDBP08678

PDB

6VB2

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6PF18 MORN3			0.564	2
UniProt:P48060 GLIPR1	2	GLIPR1 [plasma membrane] (R-HSA-561145) GLIPR1 [azurophil granule membrane] (R-HSA-6799156)	0.564	2
UniProt:P36508 ZNF76			0.556	3
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.556	3
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2
UniProt:O43309 ZSC12			0.527	2
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.527	2
UniProt:Q9BZQ6 EDEM3	1	EDEM3 [endoplasmic reticulum quality control compartment] (R-HSA-1022110)	0.527	2
UniProt:Q2M243 CCD27			0.527	2
UniProt:Q7L190 DPPA4	1	DPPA4 [nucleoplasm] (R-HSA-452999)	0.527	2
UniProt:Q8NFP9 NBEA	2	NBEA [nucleoplasm] (R-HSA-9667634) NBEA [cytosol] (R-HSA-9667627)	0.527	2
UniProt:O75752 B3GALNT1	1	B3GALNT1 [Golgi membrane] (R-HSA-8878918)	0.527	2
UniProt:O75342 ALOX12B	1	ALOX12B [cytosol] (R-HSA-2142832)	0.471	2

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