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ALOX12B [cytosol]
Stable Identifier
R-HSA-2142832
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Arachidonate 12-lipoxygenase, 12R-type, LX12B_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonate metabolism (Homo sapiens)
Synthesis of 12-eicosatetraenoic acid derivatives (Homo sapiens)
Arachidonate is oxidised to 12R-HpETE by ALOX12B (Homo sapiens)
ALOX12B:Fe2+ [cytosol] (Homo sapiens)
ALOX12B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75342 ALOX12B
Gene Names
ALOX12B
Chain
chain:1-701
Reference Genes
BioGPS Gene:242 ALOX12B
COSMIC (genes):ALOX12B ALOX12B
CTD Gene:242 ALOX12B
dbSNP Gene:242 ALOX12B
ENSEMBL:ENSG00000179477 ALOX12B
ENSEMBL_homo_sapiens_GENE:ENSG00000179477.11 ALOX12B
HGNC:430 ALOX12B
KEGG Gene (Homo sapiens):242 ALOX12B
Monarch:242 ALOX12B
NCBI Gene:242 ALOX12B
OMIM:603741 ALOX12B
UCSC:O75342 ALOX12B
Reference Transcript
RefSeq:NM_001139.2 ALOX12B
Other Identifiers
11740549_at
16840799
207381_PM_at
207381_at
242
33029_at
3744073
3744074
3744076
3744077
3744079
3744080
3744081
3744082
3744084
3744085
3744087
3744088
3744089
3744090
3744091
3744092
3744093
8012309
A_23_P83634
GE54325
GO:0001676
GO:0003824
GO:0004052
GO:0005506
GO:0005515
GO:0005737
GO:0005829
GO:0006497
GO:0006629
GO:0006631
GO:0006665
GO:0006690
GO:0010628
GO:0016491
GO:0016702
GO:0016829
GO:0016853
GO:0019369
GO:0019372
GO:0023052
GO:0034440
GO:0036211
GO:0043226
GO:0043231
GO:0043410
GO:0043651
GO:0046513
GO:0046872
GO:0047677
GO:0048471
GO:0048856
GO:0051122
GO:0051213
GO:0061436
GO:0070257
GO:0106237
GO:1990136
HMNXSV003033336
ILMN_1692332
PH_hs_0008241
TC17001100.hg
g4502052_3p_at
Participates
as a component of
ALOX12B:Fe2+ [cytosol] (Homo sapiens)
Inferred To
lipA [cytosol]
(Dictyostelium discoideum)
Homologues of ALOX12B [cytosol]
(Dictyostelium discoideum)
Homologues of ALOX12B [cytosol]
(Xenopus tropicalis)
ALOX12B [cytosol]
(Bos taurus)
ALOX12B [cytosol]
(Canis familiaris)
ALOX12B [cytosol]
(Danio rerio)
ALOX12B [cytosol]
(Dictyostelium discoideum)
ALOX12B [cytosol]
(Gallus gallus)
ALOX12B [cytosol]
(Mus musculus)
ALOX12B [cytosol]
(Rattus norvegicus)
ALOX12B [cytosol]
(Sus scrofa)
ALOX12B [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001130.1
Guide to Pharmacology - Targets
1386
OpenTargets
ENSG00000179477
HPA
ENSG00000179477-ALOX12B
GeneCards
O75342
Ensembl
ENSP00000497784
,
ENST00000647874
,
ENSG00000179477
PRO
O75342
Pharos - Targets
O75342
Orphanet
15502
HMDB Protein
HMDBP03129
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15915 ZIC1
1
ZIC1 [nucleoplasm]
(R-HSA-9731648)
0.527
2
UniProt:Q7L190 DPPA4
1
DPPA4 [nucleoplasm]
(R-HSA-452999)
0.527
2
UniProt:P01160 NPPA
5
NPPA(124-151) [extracellular region]
(R-HSA-5578799)
NPPA(1-151) [extracellular region]
(R-HSA-976950)
NPPA(1-25) [extracellular region]
(R-HSA-5578791)
NPPA(56-123) [extracellular region]
(R-HSA-5578797)
NPPA(26-55) [extracellular region]
(R-HSA-5578794)
0.527
2
UniProt:Q9BYJ1 ALOXE3
1
ALOXE3 [cytosol]
(R-HSA-8942204)
0.471
2
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