Reactome | DPPA4 [nucleoplasm]

DPPA4 [nucleoplasm]

Stable Identifier

R-HSA-452999

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Developmental pluripotency-associated protein 4, DPPA4_HUMAN

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External Reference Information

External Reference

UniProt:Q7L190 DPPA4

Gene Names

DPPA4

Chain

chain:1-304

Reference Genes

BioGPS Gene:55211 DPPA4

COSMIC (genes):DPPA4 DPPA4

CTD Gene:55211 DPPA4

dbSNP Gene:55211 DPPA4

ENSEMBL:ENSG00000121570 DPPA4

HGNC:19200 DPPA4

Monarch:55211 DPPA4

NCBI Gene:55211 DPPA4

OMIM:614125 DPPA4

UCSC:Q7L190 DPPA4

Reference Transcript

RefSeq:NM_018189.3 DPPA4

Other Identifiers

11736127_s_at

11736128_a_at

11748881_x_at

11761755_at

16957263

219651_PM_at

219651_at

232985_PM_s_at

232985_s_at

2688181

2688182

2688183

2688184

2688185

2688186

2688187

2688188

2688189

2688190

2688191

2688192

2688193

2688194

2688197

2688199

47576_at

47577_at

55211

79675_at

8089448

A_23_P380526

GE55834

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0043226

GO:0048731

GO:0048856

GO:0060484

HMNXSV003047935

Hs.9536.1.S1_3p_a_at

ILMN_1768721

PH_hs_0032640

TC03001638.hg

g8922611_3p_at

Participates

as an output of

Expression of DPPA4 (Homo sapiens)

as an input of

DPPA2, DPPA4 and TP53 bind the DUX4 gene cluster (Homo sapiens)

as a component of

DPPA2:DPPA4:p-S15-TP53:DUX4 gene [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000121570

ENSEMBL

ENST00000335658, ENSP00000335306

HPA

ENSG00000121570-DPPA4

PRO

Q7L190

Pharos - Targets

Q7L190

Interactors (36)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99961 SH3GL1	1	SH3GL1 [cytosol] (R-HSA-8867732)	0.899	10
UniProt:O95751 LDOC1			0.781	7
UniProt:P46108 CRK	1	CRK [cytosol] (R-HSA-2980677)	0.666	4
UniProt:Q12161 PSH1			0.61	4
UniProt:Q969Y2 GTPBP3	1	GTPBP3 [mitochondrial matrix] (R-HSA-6787414)	0.556	3
UniProt:Q96JC9 EAF1	1	EAF1 [nucleoplasm] (R-HSA-8932787)	0.556	3
UniProt:Q13588 GRAP	1	GRAP [cytosol] (R-HSA-1433547)	0.556	3
UniProt:Q15025 TNIP1	1	TNIP1 [cytosol] (R-HSA-5690853)	0.556	3
UniProt:Q14511-2 NEDD9			0.556	3
UniProt:Q6PIV2 FOXR1			0.556	3
UniProt:Q9Y5P6 GMPPB	1	GMPPB [cytosol] (R-HSA-532525)	0.556	3
UniProt:Q14240-2 EIF4A2			0.556	3
UniProt:Q9UKI8 TLK1			0.556	3
UniProt:Q8WV41 SNX33			0.556	5
UniProt:Q6FGM0 Q6FGM0			0.556	5
UniProt:Q14240 EIF4A2	1	EIF4A2 [cytosol] (R-HSA-72575)	0.556	3
UniProt:P61326 MAGOH	1	MAGOH [nucleoplasm] (R-HSA-156658)	0.556	3
UniProt:P38744	1	PCBD1 [cytosol] (R-SCE-71131)	0.556	3
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.556	3
UniProt:Q5MJ10 SPXN2			0.556	3
UniProt:Q96RF0 SNX18	1	SNX18 [cytosol] (R-HSA-8868038)	0.556	3
UniProt:Q9H8E8 KAT14	1	KAT14 [nucleoplasm] (R-HSA-3301917)	0.556	3
IntAct:EBI-22315148 CCSB ORF ID			0.556	3
UniProt:Q8IVT2 MISP			0.556	3
UniProt:Q86X95-2 CIR1			0.556	3
UniProt:Q9C086 INO80B	1	INO80B [nucleoplasm] (R-HSA-5689599)	0.556	3
UniProt:Q96KN7 RPGR1			0.556	3
UniProt:P22735 TGM1	3	TGM1 [cytosol] (R-HSA-6813756) TGM1 [cornified envelope] (R-HSA-8847706) TGM1 [plasma membrane] (R-HSA-6813757)	0.527	2
UniProt:Q6SPF0 SAMD1			0.527	2
UniProt:Q9Y5X1 SNX9	3	SNX9 [cytosol] (R-HSA-8867737) SNX9 [Golgi membrane] (R-HSA-432988) SNX9 [cytoplasmic vesicle membrane] (R-HSA-432990)	0.527	2
UniProt:Q53EQ6 TIGD5			0.527	2
UniProt:Q8NEX9 SDR9C7	1	SDR9C7 [endoplasmic reticulum membrane] (R-HSA-4084690)	0.527	2
UniProt:O75342 ALOX12B	1	ALOX12B [cytosol] (R-HSA-2142832)	0.527	2
UniProt:Q9BYJ1 ALOXE3	1	ALOXE3 [cytosol] (R-HSA-8942204)	0.527	2
UniProt:P05090 APOD	1	APOD [extracellular region] (R-HSA-5216199)	0.527	2
UniProt:P42357 HAL	1	HAL [cytosol] (R-HSA-70897)	0.527	3

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