Reactome | N-aspartyl-glycosylphosphatidylinositolethanolamine-TDGF1(31-188) [plasma membrane]

N-aspartyl-glycosylphosphatidylinositolethanolamine-TDGF1(31-188) [plasma membrane]

Stable Identifier

R-HSA-452300

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

CRIPTO, TDGF1 (CRIPTO), Teratocarcinoma-derived growth factor 1, TDGF1_HUMAN, TDGF1

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External Reference Information

External Reference

UniProt:P13385 TDGF1

Gene Names

TDGF1, CRIPTO, TDGF1

Chain

signal peptide:1-30, chain:31-150, propeptide:151-188

Reference Genes

BioGPS Gene:6997 TDGF1

COSMIC (genes):TDGF1 TDGF1

CTD Gene:6997 TDGF1

dbSNP Gene:6997 TDGF1

ENSEMBL:ENSG00000241186 TDGF1

HGNC:11701 TDGF1

KEGG:hsa:6997 TDGF1

Monarch:6997 TDGF1

NCBI Gene:6997 TDGF1

OMIM:187395 TDGF1

UCSC:P13385 TDGF1

Reference Transcript

Other Identifiers

11746022_s_at

16940211

206286_PM_s_at

206286_s_at

2620941

2620943

2620944

2620945

2620946

2620947

2620948

2620949

2620950

3833155

3987169

40386_r_at

6997

8079422

A_14_P104624

A_23_P366376

GE59714

GE79797

GO:0001568

GO:0001763

GO:0002042

GO:0005102

GO:0005515

GO:0005576

GO:0005615

GO:0005886

GO:0007165

GO:0007368

GO:0007507

GO:0008083

GO:0008284

GO:0008595

GO:0009792

GO:0009952

GO:0009966

GO:0009986

GO:0010595

GO:0016324

GO:0018105

GO:0019897

GO:0030154

GO:0030335

GO:0030879

GO:0035729

GO:0038092

GO:0038100

GO:0043066

GO:0043406

GO:0043410

GO:0044344

GO:0045121

GO:0048018

GO:0048856

GO:0048870

GO:0050731

GO:0070697

GO:0071346

GO:0071354

GO:0071356

GO:0071364

GO:0098552

GO:0098772

HMNXSV003026987

ILMN_1782862

ILMN_1795681

ILMN_2132379

TC03003403.hg

X14253_s_at

g4507424_3p_a_at

Participates

as an output of

Expression of TDGF1 (CRIPTO) (Homo sapiens)

as a member of

EGF-CFC Coreceptor [plasma membrane] (Homo sapiens)

Modified Residues

Name

N-aspartyl-glycosylphosphatidylinositolethanolamine at 150

Coordinate

150

PsiMod Name

N-aspartyl-glycosylphosphatidylinositolethanolamine

PsiMod Definition

A protein modification that effectively converts an L-aspartic acid residue to N-(aspart-1-yl)-glycosylphosphatidylinositolethanolamine.

Cross References

RefSeq

NP_003203.1, NP_001167607.1

ENSEMBL

ENSP00000296145, ENST00000296145

OpenTargets

ENSG00000241186

HPA

ENSG00000241186-TDGF1

PRO

P13385

Pharos - Targets

P13385

GlyGen

P13385

Orphanet

CRIPTO

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H871 RMND5A	1	RMND5A [cytosol] (R-HSA-9861580)	0.527	3
UniProt:Q96E35 ZMY19			0.527	3
UniProt:Q9H173 SIL1			0.527	3
UniProt:Q9UL63 MKLN1	1	Muskelin [cytosol] (R-HSA-9861557)	0.527	3
UniProt:Q96G75 RMND5B	1	RMND5B [cytosol] (R-HSA-9861550)	0.527	2
UniProt:Q9NWU2 GID8	1	GID8 [cytosol] (R-HSA-9861665)	0.527	3
UniProt:Q6P9A2 GALNT18	1	GALNT18 [Golgi membrane] (R-HSA-913685)	0.527	3
UniProt:Q9BTN0 LRFN3	1	SALM4 [plasma membrane] (R-HSA-197704)	0.527	3
UniProt:Q14116 IL18	4	IL18 [extracellular region] (R-HSA-448446) IL18(1-36) [cytosol] (R-HSA-449062) IL18 [cytosol] (R-HSA-449023) IL18(1-193) [cytosol] (R-HSA-449033)	0.527	2
UniProt:O00170 AIP	2	AIP [nucleoplasm] (R-HSA-8937156) AIP [cytosol] (R-HSA-8936839)	0.527	3
UniProt:Q6VN20 RANBP10	1	RANBP10 [cytosol] (R-HSA-8851865)	0.527	3
UniProt:Q8IVV7 GID4	1	GID4 [cytosol] (R-HSA-9861538)	0.527	3