TBC1D11 binds RAB6

Stable Identifier
Reaction [binding]
Homo sapiens
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Rab6 is associated with Golgi and trans-Golgi (TGN) membranes in interphase and regulates a retrograde transport route connecting early endosomes to the endoplasmic reticulum (ER). TBC domain family, member 11 (TBC1D11 also referred as GAPCENA is a Rab GTPase and directly binds Rab6 via its N-terminal PTB domain (Cuif et al. 1999, Miserey-Lenkei et al. 2006).

Literature References
PubMed ID Title Journal Year
16395330 A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint

Miserey-Lenkei, S, Cou√ędel-Courteille, A, Sibarita, JB, Bardin, S, Goud, B, Racine, V, Bornens, M, Perez, F, del Nery, E, Piel, M

EMBO J. 2006
10202141 Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome

Bornens, M, Langsley, G, Cuif, MH, Janoueix-Lerosey, I, Bordes, N, Goud, B, Possmayer, F, Zander, H, Jollivet, F, Couedel-Courteille, A

EMBO J. 1999
Orthologous Events
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