Reactome | KRTAP12-3 [cytosol]

KRTAP12-3 [cytosol]

Stable Identifier

R-HSA-6810284

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 12-3, KR123_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP12s [cytosol] (Homo sapiens)
        
        KRTAP12-3 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP12s [cytosol] (Homo sapiens)
        
        KRTAP12-3 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P60328 KRTAP12-3

Gene Names

KRTAP12-3, KAP12.3, KRTAP12.3

Chain

chain:1-96

Reference Genes

BioGPS Gene:386683 KRTAP12-3

COSMIC (genes):KRTAP12-3 KRTAP12-3

CTD Gene:386683 KRTAP12-3

dbSNP Gene:386683 KRTAP12-3

ENSEMBL:ENSG00000205439 KRTAP12-3

ENSEMBL_homo_sapiens_GENE:ENSG00000205439.10 KRTAP12-3

HGNC:20531 KRTAP12-3

KEGG Gene (Homo sapiens):386683 KRTAP12-3

Monarch:386683 KRTAP12-3

NCBI Gene:386683 KRTAP12-3

UCSC:P60328 KRTAP12-3

Reference Transcript

RefSeq:NM_198697.2 KRTAP12-3

Other Identifiers

11738963_at

16923670

386683

3923882

3923883

3923884

3923885

3923886

8069161

A_33_P3354399

GO:0005515

GO:0005829

GO:0005856

GO:0005882

GO:0042802

GO:0043226

GO:0045095

HMNXSV003051843

ILMN_1714028

PH_hs_0034605

TC21000236.hg

TC21001074.hg

Participates

as a member of

KRTAP12s [cytosol] (Homo sapiens)

Inferred To

LOC110256282 [cytosol] (Sus scrofa)

KRTAP12-3 [cytosol] (Bos taurus)

KRTAP12-2 [cytosol] (Bos taurus)

LOC106508044 [cytosol] (Sus scrofa)

LOC610887 [cytosol] (Canis familiaris)

Gm10024 [cytosol] (Mus musculus)

LOC112448008 [cytosol] (Bos taurus)

Gm10100 [cytosol] (Mus musculus)

LOC782628 [cytosol] (Bos taurus)

Gm10142 [cytosol] (Mus musculus)

Homologues of KRTAP12-3 [cytosol] (Bos taurus)

Homologues of KRTAP12-3 [cytosol] (Mus musculus)

Homologues of KRTAP12-3 [cytosol] (Sus scrofa)

Krtap12-1 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_941970.2

OpenTargets

ENSG00000205439

GeneCards

P60328

HPA

ENSG00000205439-KRTAP12-3

Ensembl

ENST00000397907, ENSG00000205439, ENSP00000381005

PRO

P60328

Pharos - Targets

P60328

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.601	4
UniProt:O96014 WNT11	9	N4GlycoAsn-PalmS WNT11 [extracellular region] (R-HSA-3247797) N4GlycoAsn-PalmS WNT11 [plasma membrane] (R-HSA-3247792) N4GlycoAsn-PalmS WNT11 [Golgi lumen] (R-HSA-3247823) N4GlycoAsn-PalmS WNT11 [endoplasmic reticulum lumen] (R-HSA-3238335) N4GlycoAsn-WNT11 [endoplasmic reticulum lumen] (R-HSA-3238222) WNT11 [endoplasmic reticulum lumen] (R-HSA-3238281) N4GlycoAsn-PalmS WNT11 [endocytic vesicle membrane] (R-HSA-3781987) N4GlycoAsn-PalmS WNT11 [extracellular exosome] (R-HSA-3781980) WNT11 [extracellular region] (R-HSA-517473)	0.556	3
UniProt:P43353 ALDH3B1	3	ALDH3B1 [plasma membrane] (R-HSA-5696096) ALDH3B1 [specific granule membrane] (R-HSA-6799510) ALDH3B1 [secretory granule membrane] (R-HSA-6801023)	0.556	3
UniProt:Q92608 DOCK2	3	DOCK2 [specific granule lumen] (R-HSA-6799558) DOCK2 [extracellular region] (R-HSA-6806310) DOCK2 [cytosol] (R-HSA-200938)	0.556	3
UniProt:P48023 FASLG	1	FASLG(1-281) [extracellular region] (R-HSA-66212)	0.556	3
UniProt:P48645 NMU	1	NMU [extracellular region] (R-HSA-964817)	0.556	3
UniProt:Q92570 NR4A3	1	NR4A3 [nucleoplasm] (R-HSA-8938004)	0.556	3
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:Q86YT5 SLC13A5	1	SLC13A5 [plasma membrane] (R-HSA-433135)	0.556	3
UniProt:Q8WUK0 DUSP23	1	PTPMT1 [mitochondrial inner membrane] (R-HSA-3446802)	0.556	3
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.556	3
UniProt:O96015 DNAL4	1	DNAL4 [plasma membrane] (R-HSA-177484)	0.556	3
UniProt:Q12837 POU4F2	1	POU4F2 [nucleoplasm] (R-HSA-6804414)	0.556	3
UniProt:Q8TDS5 OXER1	1	OXER1 [plasma membrane] (R-HSA-416425)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	6
UniProt:P15018 LIF	1	LIF [extracellular region] (R-HSA-5696436)	0.556	3
UniProt:P41222 PTGDS	1	PTGDS [endoplasmic reticulum membrane] (R-HSA-2142814)	0.556	3
UniProt:P07237 P4HB	3	P4HB [endoplasmic reticulum lumen] (R-HSA-174692) p-P4HB [endoplasmic reticulum lumen] (R-HSA-8956902) HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287)	0.556	3
UniProt:Q7Z7K2 ZNF467	1	ZNF467 [nucleoplasm] (R-HSA-8940332)	0.556	3
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.556	3
UniProt:Q15077 P2RY6	1	P2RY6 [plasma membrane] (R-HSA-417924)	0.556	3

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