Reactome | pro-HGF [extracellular region]

Stable Identifier

R-HSA-6800218

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

HGF(32-728), Hepatocyte growth factor alpha chain, Scatter factor, SF, Hepatopoeitin A

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P14210 HGF

Gene Names

HGF, HPTA

Chain

signal peptide:1-31, chain:32-494, chain:495-728

Reference Genes

COSMIC (genes):HGF HGF

dbSNP Gene:3082 HGF

ENSEMBL:ENSG00000019991 HGF

Participates

as an input of

Other forms of this molecule

HGF(495-728) [extracellular region]

HGF(32-494) [extracellular region]

Inferred To

Hgf [extracellular region] (Mus musculus)

Hgf [extracellular region] (Rattus norvegicus)

pro-HGF [extracellular region] (Gallus gallus)

HGF [extracellular region] (Bos taurus)

HGF [extracellular region] (Canis familiaris)

HGF [extracellular region] (Sus scrofa)

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08581 MET	7	p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-6806973) MET [plasma membrane] (R-HSA-419603) p-Y1003,4Y-MET [plasma membrane] (R-HSA-8874689) p-Y1234,Y1235,Y1356-MET [plasma membrane] (R-HSA-6807014) MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (R-HSA-8875180) MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-8875181) p-Y1349,Y1356-MET [plasma membrane] (R-HSA-6807032)	0.851	7
UniProt:P14210 HGF	5	HGF(32-494) [platelet alpha granule lumen] (R-HSA-139866) HGF(495-728) [platelet alpha granule lumen] (R-HSA-141764) pro-HGF [extracellular region] (R-HSA-6800218) HGF(495-728) [extracellular region] (R-HSA-141767) HGF(32-494) [extracellular region] (R-HSA-56497)	0.623	2
UniProt:P16056	7	phospho-p-Y1349,Y1356-MET [plasma membrane] (R-MMU-6807032) phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-MMU-8875181) phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (R-MMU-8875180) phospho-p-Y1234,Y1235,Y1356-MET [plasma membrane] (R-MMU-6807014) phospho-p-Y1003,4Y-MET [plasma membrane] (R-MMU-8874689) MET [plasma membrane] (R-MMU-419603) phospho-p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-MMU-6806973)	0.558	2
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:P50222 MEOX2			0.556	3

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