Reactome | RNF20 [nucleoplasm]

RNF20 [nucleoplasm]

Stable Identifier

R-HSA-5689011

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

E3 ubiquitin-protein ligase BRE1A, BRE1A_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5VTR2 RNF20

Gene Names

RNF20, BRE1A

Chain

chain:1-975

Reference Genes

BioGPS Gene:56254 RNF20

COSMIC (genes):RNF20 RNF20

CTD Gene:56254 RNF20

dbSNP Gene:56254 RNF20

ENSEMBL:ENSG00000155827 RNF20

HGNC:10062 RNF20

KEGG:hsa:56254 RNF20

Monarch:56254 RNF20

NCBI Gene:56254 RNF20

OMIM:607699 RNF20

UCSC:Q5VTR2 RNF20

Reference Transcript

Other Identifiers

11758375_s_at

17087647

222683_PM_at

222683_at

3182509

3182510

3182512

3182513

3182514

3182515

3182516

3182517

3182518

3182520

3182522

3182523

3182524

3182526

3182529

3182530

3182531

3182532

3182533

3182534

3182535

3182536

3182537

3182538

3182539

3182540

3182541

3182542

3182543

56254

8156945

90639_at

A_14_P135374

A_24_P98385

GE56003

GE88753

GO:0000151

GO:0000209

GO:0002039

GO:0003682

GO:0003713

GO:0003723

GO:0003730

GO:0003824

GO:0004842

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0006325

GO:0006338

GO:0006355

GO:0006511

GO:0016567

GO:0016740

GO:0030336

GO:0031625

GO:0033503

GO:0042393

GO:0042802

GO:0043226

GO:0045893

GO:0045944

GO:0046872

GO:0060090

GO:0061630

GO:0140096

GO:0140110

GO:0140850

HMNXSV003020215

Hs.168095.0.S2_3p_at

ILMN_1710758

PH_hs_0029304

TC09000519.hg

Participates

as a component of

RNF20:RNF40 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

RNF20 [cytosol]

Inferred To

bre1 [nucleoplasm] (Dictyostelium discoideum)

Homologues of RNF20 [nucleoplasm] (Schizosaccharomyces pombe)

BRE1 [nucleoplasm] (Saccharomyces cerevisiae)

RNF20 [nucleoplasm] (Bos taurus)

RNF20 [nucleoplasm] (Canis familiaris)

RNF20 [nucleoplasm] (Gallus gallus)

RNF20 [nucleoplasm] (Sus scrofa)

brl1 [nucleoplasm] (Schizosaccharomyces pombe)

rfp-1 [nucleoplasm] (Caenorhabditis elegans)

Rnf20 [nucleoplasm] (Mus musculus)

Rnf20 [nucleoplasm] (Rattus norvegicus)

Bre1 [nucleoplasm] (Drosophila melanogaster)

brl2 [nucleoplasm] (Schizosaccharomyces pombe)

rnf20 [nucleoplasm] (Danio rerio)

rnf20 [nucleoplasm] (Xenopus tropicalis)

Cross References

ENSEMBL

ENSG00000155827, ENST00000389120, ENSP00000373772

OpenTargets

ENSG00000155827

GeneCards

RNF20

HPA

ENSG00000155827-RNF20

PRO

Q5VTR2

Pharos - Targets

Q5VTR2

GlyGen

Q5VTR2

HMDB Protein

HMDBP09296

PDB

8IEJ, 8GUI, 8GUJ, 5TRB

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.742	24
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.556	3
UniProt:Q9Y6A5 TACC3	1	TACC3 [cytosol] (R-HSA-2160956)	0.556	3
UniProt:Q6P1J9 CDC73	1	CDC73 [nucleoplasm] (R-HSA-3322360)	0.556	3
UniProt:P51665 PSMD7	5	PSMD7 [cytosol] (R-HSA-68806) PSMD7 [nucleoplasm] (R-HSA-174309) PSMD7 [ficolin-1-rich granule lumen] (R-HSA-6800406) PSMD7 [extracellular region] (R-HSA-6806488) PSMD7 [secretory granule lumen] (R-HSA-6801008)	0.527	2
UniProt:Q9BTA9 WAC	1	WAC [nucleoplasm] (R-HSA-8942150)	0.527	2
UniProt:O96017 CHEK2	3	p-S,3T-CHEK2 [nucleoplasm] (R-HSA-5683784) CHEK2 [nucleoplasm] (R-HSA-113824) p-T68-CHEK2 [nucleoplasm] (R-HSA-113825)	0.508	3

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