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BBS5 [cytosol]
Stable Identifier
R-HSA-5617633
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
GO Cellular Component
ciliary basal body
(0036064)
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
BBSome-mediated cargo-targeting to cilium (Homo sapiens)
ARL6:GTP and the BBSome bind ciliary cargo (Homo sapiens)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
ARL6:GTP and the BBSome target cargo to the primary cilium (Homo sapiens)
ARL6:GTP:BBSome:ciliary cargo [ciliary membrane] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
BBSome binds RAB3IP (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
RAB3IP:BBSome [ciliary basal body] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
Formation of the BBSome (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
LZTFL1 binds the BBSome and prevents its traffic to the cilium (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N3I7 BBS5
Gene Names
BBS5
Chain
chain:1-341
Reference Genes
BioGPS Gene:129880 BBS5
COSMIC (genes):BBS5 BBS5
CTD Gene:129880 BBS5
dbSNP Gene:129880 BBS5
ENSEMBL:ENSG00000163093 BBS5
HGNC:970 BBS5
Monarch:129880 BBS5
NCBI Gene:129880 BBS5
OMIM:603650 BBS5
UCSC:Q8N3I7 BBS5
Reference Transcript
RefSeq:NM_152384.2 BBS5
Other Identifiers
11731014_a_at
129880
16887259
230697_PM_at
230697_at
2514375
2514376
2514379
2514380
2514381
2514382
2514383
2514384
2514386
2514387
2514388
2514389
2514391
2514392
2514394
2514396
2514397
2514398
2514399
2514400
2514401
2514402
2514403
2514404
2519406
3559805
3559810
73240_r_at
74424_at
8046147
A_14_P120157
A_14_P201511
A_23_P5785
A_24_P208452
GE506688
GO:0001947
GO:0005515
GO:0005737
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0005929
GO:0005930
GO:0007601
GO:0008289
GO:0015031
GO:0030030
GO:0032266
GO:0032402
GO:0034451
GO:0034464
GO:0036064
GO:0043226
GO:0044458
GO:0044782
GO:0046907
GO:0050877
GO:0060170
GO:0060271
GO:0061629
HMNXSV003043279
Hs.99148.0.A1_3p_at
Hs.99148.0.A1_3p_x_at
ILMN_1663592
ILMN_1711053
ILMN_2299737
PH_hs_0040758
TC02005001.hg
Participates
as an input of
Formation of the BBSome (Homo sapiens)
as a component of
BBSome [cytosol] (Homo sapiens)
Inferred To
Bbs5 [cytosol]
(Mus musculus)
bbs-5 [cytosol]
(Caenorhabditis elegans)
BBS5 [cytosol]
(Bos taurus)
BBS5 [cytosol]
(Canis familiaris)
BBS5 [cytosol]
(Gallus gallus)
BBS5 [cytosol]
(Rattus norvegicus)
BBS5 [cytosol]
(Sus scrofa)
bbs5 [cytosol]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000376431
,
ENST00000392663
,
ENSP00000295240
,
ENST00000295240
OpenTargets
ENSG00000163093
HPA
ENSG00000163093-BBS5
PRO
Q8N3I7
Pharos - Targets
Q8N3I7
Orphanet
BBS5
PDB
6XTB
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q3SYG4 BBS9
1
BBS9 [cytosol]
(R-HSA-5617630)
0.889
10
UniProt:Q96RK4 BBS4
1
BBS4 [cytosol]
(R-HSA-5617635)
0.879
10
UniProt:Q8NFJ9 BBS1
1
BBS1 [cytosol]
(R-HSA-5617640)
0.865
11
UniProt:Q9BXC9 BBS2
1
BBS2 [cytosol]
(R-HSA-5617637)
0.839
9
UniProt:Q8TAM2 TTC8
1
TTC8 [cytosol]
(R-HSA-5617600)
0.789
6
UniProt:Q8IWZ6 BBS7
1
BBS7 [cytosol]
(R-HSA-5617632)
0.789
9
UniProt:Q9NQ48 LZTFL1
1
LZTFL1 [cytosol]
(R-HSA-5617789)
0.638
3
UniProt:Q15051 IQCB1
1
IQCB1 [cytosol]
(R-HSA-5626648)
0.571
8
IntAct:EBI-10171556 147700
0.556
3
UniProt:Q6P597 KLC3
1
KLC3 [cytosol]
(R-HSA-983232)
0.556
3
UniProt:P78560 CRADD
1
CRADD [cytosol]
(R-HSA-5657970)
0.556
3
UniProt:P48556 PSMD8
2
PSMD8 [cytosol]
(R-HSA-68808)
PSMD8 [nucleoplasm]
(R-HSA-174318)
0.508
2
UniProt:A8MTZ0 BBIP1
1
BBIP1 [cytosol]
(R-HSA-5618167)
0.508
2
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