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LZTFL1 [cytosol]
Stable Identifier
R-HSA-5617789
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
BBSome-mediated cargo-targeting to cilium (Homo sapiens)
ARL6:GTP and the BBSome target cargo to the primary cilium (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
LZTFL1 oligomer [cytosol] (Homo sapiens)
LZTFL1 [cytosol] (Homo sapiens)
LZTFL1 binds the BBSome and prevents its traffic to the cilium (Homo sapiens)
LZTFL1 oligomer [cytosol] (Homo sapiens)
LZTFL1 [cytosol] (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
LZTFL1 oligomer [cytosol] (Homo sapiens)
LZTFL1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NQ48 LZTFL1
Gene Names
LZTFL1
Chain
chain:1-299
Reference Genes
BioGPS Gene:54585 LZTFL1
COSMIC (genes):LZTFL1 LZTFL1
CTD Gene:54585 LZTFL1
dbSNP Gene:54585 LZTFL1
ENSEMBL:ENSG00000163818 LZTFL1
ENSEMBL_homo_sapiens_GENE:ENSG00000163818.20 LZTFL1
HGNC:6741 LZTFL1
KEGG Gene (Homo sapiens):54585 LZTFL1
Monarch:54585 LZTFL1
NCBI Gene:54585 LZTFL1
OMIM:606568 LZTFL1
UCSC:Q9NQ48 LZTFL1
Reference Transcript
RefSeq:XM_017006644.1 LZTFL1
RefSeq:NM_001276379.1 LZTFL1
RefSeq:NM_001276378.1 LZTFL1
RefSeq:XM_011533838.2 LZTFL1
RefSeq:NM_020347.3 LZTFL1
Other Identifiers
11743772_a_at
11743773_s_at
11743774_a_at
16952818
218437_PM_s_at
218437_s_at
222632_PM_s_at
222632_s_at
237553_PM_at
237553_at
2671972
2671973
2671974
2671975
2671976
2671977
2671978
2671979
2671980
2671983
2671987
2671988
2671989
2671992
2671993
2671995
2671997
2671999
2672001
2672013
2672015
51201_at
54585
56175_at
8086555
83198_at
A_23_P41049
A_24_P37519
GE495348
GE62461
GO:0002177
GO:0005515
GO:0005737
GO:0005829
GO:0005856
GO:0005929
GO:0007018
GO:0007283
GO:0022414
GO:0030317
GO:0042802
GO:0043226
GO:0044877
GO:0048870
GO:1903565
GO:1903568
HMNXSV003019098
Hs.174746.0.A1_3p_at
Hs.30824.0.S1_3p_a_at
ILMN_1815705
PH_hs_0002631
TC03001352.hg
g9966792_3p_a_at
Participates
as a component of
LZTFL1 oligomer [cytosol] (Homo sapiens)
Inferred To
LZTFL1 [cytosol]
(Bos taurus)
LZTFL1 [cytosol]
(Canis familiaris)
LZTFL1 [cytosol]
(Gallus gallus)
LZTFL1 [cytosol]
(Sus scrofa)
Lztfl1 [cytosol]
(Mus musculus)
Lztfl1 [cytosol]
(Rattus norvegicus)
Ghost homologue of LZTFL1 [cytosol]
(Caenorhabditis elegans)
lztfl1 [cytosol]
(Danio rerio)
lztfl1 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
XP_016862133.1
,
NP_001263307.1
,
XP_011532140.1
,
NP_001263308.1
,
NP_065080.1
OpenTargets
ENSG00000163818
HPA
ENSG00000163818-LZTFL1
GeneCards
Q9NQ48
Ensembl
ENSP00000441784
,
ENSP00000296135
,
ENSG00000163818
,
ENST00000684620
,
ENST00000539217
,
ENST00000296135
,
ENSP00000506925
PRO
Q9NQ48
Pharos - Targets
Q9NQ48
Orphanet
21170
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q3SYG4 BBS9
1
BBS9 [cytosol]
(R-HSA-5617630)
0.845
11
UniProt:Q9BXC9 BBS2
1
BBS2 [cytosol]
(R-HSA-5617637)
0.789
6
UniProt:Q8IWZ6 BBS7
1
BBS7 [cytosol]
(R-HSA-5617632)
0.789
6
UniProt:O00560 SDCBP
3
SDCBP [extracellular region]
(R-HSA-6806206)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [cytosol]
(R-HSA-373639)
0.718
6
UniProt:Q8N3I7 BBS5
1
BBS5 [cytosol]
(R-HSA-5617633)
0.638
3
UniProt:P25786 PSMA1
2
PSMA1 [nucleoplasm]
(R-HSA-174333)
PSMA1 [cytosol]
(R-HSA-68724)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
5
UniProt:P20618 PSMB1
7
PSMB1(1-28) [cytosol]
(R-HSA-9908143)
pro-PSMB1 [cytosol]
(R-HSA-9908139)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
PSMB1 [nucleoplasm]
(R-HSA-174347)
PSMB1 [cytosol]
(R-HSA-68738)
0.556
3
UniProt:Q08426 EHHADH
2
EHHADH [peroxisomal matrix]
(R-HSA-400155)
EHHADH [cytosol]
(R-HSA-9033147)
0.556
3
UniProt:Q8TAM2 TTC8
1
TTC8 [cytosol]
(R-HSA-5617600)
0.508
3
UniProt:Q8NFJ9 BBS1
1
BBS1 [cytosol]
(R-HSA-5617640)
0.508
3
UniProt:O43684 BUB3
1
BUB3 [cytosol]
(R-HSA-141416)
0.508
2
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