Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
BBS7 [cytosol]
Stable Identifier
R-HSA-5617632
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
BBS2L1
GO Cellular Component
ciliary basal body
(0036064)
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
BBSome-mediated cargo-targeting to cilium (Homo sapiens)
ARL6:GTP and the BBSome bind ciliary cargo (Homo sapiens)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
ARL6:GTP and the BBSome target cargo to the primary cilium (Homo sapiens)
ARL6:GTP:BBSome:ciliary cargo [ciliary membrane] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
BBSome binds RAB3IP (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
RAB3IP:BBSome [ciliary basal body] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
Formation of the BBSome (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
LZTFL1 binds the BBSome and prevents its traffic to the cilium (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
LZTFL1 oligomer:BBSome [cytosol] (Homo sapiens)
BBSome [cytosol] (Homo sapiens)
BBS7 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IWZ6 BBS7
Gene Names
BBS7, BBS2L1
Chain
chain:1-715
Reference Genes
BioGPS Gene:55212 BBS7
COSMIC (genes):BBS7 BBS7
CTD Gene:55212 BBS7
dbSNP Gene:55212 BBS7
ENSEMBL:ENSG00000138686 BBS7
ENSEMBL:ENSG00000138686.10 BBS7
HGNC:18758 BBS7
KEGG Gene (Homo sapiens):55212 BBS7
Monarch:55212 BBS7
NCBI Gene:55212 BBS7
OMIM:607590 BBS7
UCSC:Q8IWZ6 BBS7
Reference Transcript
RefSeq:NM_018190.3 BBS7
RefSeq:NM_176824.2 BBS7
Other Identifiers
11728609_a_at
11728610_at
11743080_at
16979526
219688_PM_at
219688_at
235007_PM_at
235007_at
2784126
2784127
2784128
2784129
2784130
2784132
2784133
2784134
2784135
2784136
2784137
2784138
2784139
2784140
2784142
2784144
2784146
2784147
2784148
2784149
2784150
2784153
2784154
2784156
2784159
2784163
2784164
2784165
2784168
2784169
47503_at
55212
64721_at
79733_at
8102655
A_23_P252913
A_24_P260361
GE82321
GO:0001654
GO:0001750
GO:0001947
GO:0005515
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0005929
GO:0005930
GO:0006351
GO:0006355
GO:0006357
GO:0007224
GO:0007368
GO:0007420
GO:0007507
GO:0007601
GO:0008104
GO:0015031
GO:0016020
GO:0023052
GO:0030030
GO:0030154
GO:0030163
GO:0032402
GO:0032436
GO:0034464
GO:0036064
GO:0042995
GO:0043005
GO:0043226
GO:0044782
GO:0045444
GO:0046907
GO:0048546
GO:0048856
GO:0050877
GO:0050896
GO:0051877
GO:0060170
GO:0060173
GO:0060271
GO:0061629
GO:1903929
GO:1905515
HMNXSV003006570
Hs.136182.0.A1_3p_at
ILMN_1703111
ILMN_1775012
ILMN_1776656
ILMN_2257833
ILMN_2377056
PH_hs_0003793
TC04001517.hg
g8922614_3p_at
Participates
as an input of
Formation of the BBSome (Homo sapiens)
as a component of
BBSome [cytosol] (Homo sapiens)
Inferred To
osm-12 [cytosol]
(Caenorhabditis elegans)
BBS7 [cytosol]
(Bos taurus)
BBS7 [cytosol]
(Canis familiaris)
BBS7 [cytosol]
(Danio rerio)
BBS7 [cytosol]
(Gallus gallus)
BBS7 [cytosol]
(Sus scrofa)
bbs7 [cytosol]
(Xenopus tropicalis)
Bbs7 [cytosol]
(Mus musculus)
Bbs7 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_060660.2
,
NP_789794.1
OpenTargets
ENSG00000138686
HPA
ENSG00000138686-BBS7
GeneCards
Q8IWZ6
Ensembl
ENST00000506636
,
ENSP00000264499
,
ENSG00000138686
,
ENSP00000423626
,
ENST00000264499
PRO
Q8IWZ6
Pharos - Targets
Q8IWZ6
Orphanet
15357
Interactors (18)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BXC9 BBS2
1
BBS2 [cytosol]
(R-HSA-5617637)
0.888
14
UniProt:Q8NFJ9 BBS1
1
BBS1 [cytosol]
(R-HSA-5617640)
0.846
8
UniProt:Q96RK4 BBS4
1
BBS4 [cytosol]
(R-HSA-5617635)
0.839
6
UniProt:Q3SYG4 BBS9
1
BBS9 [cytosol]
(R-HSA-5617630)
0.76
7
UniProt:Q9NQ48 LZTFL1
1
LZTFL1 [cytosol]
(R-HSA-5617789)
0.725
4
UniProt:Q8N3I7 BBS5
1
BBS5 [cytosol]
(R-HSA-5617633)
0.725
6
UniProt:Q6ZW61 BBS12
1
BBS12 [cytosol]
(R-HSA-5624082)
0.723
7
UniProt:Q8TAM1 BBS10
1
BBS10 [cytosol]
(R-HSA-5624080)
0.677
4
UniProt:Q9NPJ1 MKKS
1
MKKS [cytosol]
(R-HSA-5624086)
0.662
7
UniProt:Q8TAM2 TTC8
1
TTC8 [cytosol]
(R-HSA-5617600)
0.638
3
UniProt:P78371 CCT2
3
CCT2 [extracellular region]
(R-HSA-6806220)
CCT2 [cytosol]
(R-HSA-390464)
CCT2 [azurophil granule lumen]
(R-HSA-6799356)
0.597
3
UniProt:P05062 ALDOB
3
ALDOB A174D [cytosol]
(R-HSA-5656456)
ALDOB A149P [cytosol]
(R-HSA-5656457)
ALDOB [cytosol]
(R-HSA-70339)
0.543
4
UniProt:Q8TAM2-4 TTC8
0.527
2
UniProt:P05412 JUN
4
JUN [nucleoplasm]
(R-HSA-450250)
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.524
3
UniProt:Q15051 IQCB1
1
IQCB1 [cytosol]
(R-HSA-5626648)
0.518
5
UniProt:Q8NDW8 TT21A
0.508
2
UniProt:P49368 CCT3
1
CCT3 [cytosol]
(R-HSA-390463)
0.462
2
UniProt:P17987 TCP1
1
TCP1 [cytosol]
(R-HSA-390448)
0.462
2
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text