Reactome | GPR161 [ciliary membrane]

GPR161 [ciliary membrane]

Stable Identifier

R-HSA-5610373

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary membrane

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External Reference Information

External Reference

UniProt:Q8N6U8 GPR161

Gene Names

GPR161

Chain

chain:1-529

Reference Genes

BioGPS Gene:23432 GPR161

COSMIC (genes):GPR161 GPR161

CTD Gene:23432 GPR161

dbSNP Gene:23432 GPR161

ENSEMBL:ENSG00000143147 GPR161

HGNC:23694 GPR161

KEGG:hsa:23432 GPR161

Monarch:23432 GPR161

NCBI Gene:23432 GPR161

OMIM:612250 GPR161

UCSC:Q8N6U8 GPR161

Reference Transcript

Other Identifiers

11742775_a_at

11742776_s_at

11749295_a_at

16696073

206971_PM_at

206971_at

206972_PM_s_at

206972_s_at

214104_PM_at

214104_at

230369_PM_at

230369_at

232350_3p_x_at

232350_PM_x_at

232350_x_at

23432

235961_PM_at

235961_at

2442913

2442914

2442915

2442916

2442917

2442918

2442919

2442920

2442921

2442922

2442924

2442925

2442926

2442927

2442928

2442929

2442930

2442931

2442932

2442939

2442946

2442947

2442948

2442949

2442952

2442954

2442957

2442958

2442959

2442960

2442961

2442962

2442963

2442964

2442965

2442966

40299_at

40300_g_at

40301_at

48259_at

55977_at

77927_i_at

77929_r_at

7922108

A_23_P103532

A_23_P303455

A_23_P354314

A_32_P497742

GE81746

GO:0004930

GO:0005515

GO:0005768

GO:0005886

GO:0005929

GO:0007186

GO:0007189

GO:0016020

GO:0030666

GO:0031410

GO:0043005

GO:0043226

GO:0055037

GO:0060089

GO:0060170

GO:0097386

GO:1901621

HMNXSV003049054

Hs.21606.0.A1_3p_at

Hs.271809.0.S1_3p_x_at

Hs.301642.1.S1_3p_at

Hs.85893.0.A1_3p_at

ILMN_1658586

ILMN_1753680

ILMN_1773940

PH_hs_0023354

PH_hs_0039137

TC01005921.hg

g6677700_3p_a_at

g6677700_3p_x_at

Participates

as an input of

as a component of

GPR161:IFT-A:TULP3 [cilium] (Homo sapiens)

Other forms of this molecule

GPR161 [endocytic vesicle membrane]

Inferred To

gpr161 [ciliary membrane] (Danio rerio)

gpr161 [ciliary membrane] (Xenopus tropicalis)

GPR161 [ciliary membrane] (Bos taurus)

GPR161 [ciliary membrane] (Canis familiaris)

GPR161 [ciliary membrane] (Gallus gallus)

GPR161 [ciliary membrane] (Sus scrofa)

Gpr161 [ciliary membrane] (Mus musculus)

Gpr161 [ciliary membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_011507678.1, XP_011507677.1, XP_005245113.1, XP_016856351.1, XP_005245114.1, NP_001254538.1, XP_005245112.1, XP_016856350.1, NP_001254539.1, XP_011507679.1, XP_016856349.1, NP_722561.1, XP_016856348.1, NP_001254542.1, NP_001254541.1, NP_001254543.1, XP_011507680.1

Guide to Pharmacology - Targets

141

OpenTargets

ENSG00000143147

ENSEMBL

ENSP00000441039, ENSP00000444348, ENSP00000506967, ENST00000367836, ENST00000367835, ENST00000537209, ENST00000539777, ENSP00000356812, ENSP00000356810, ENST00000682931, ENSP00000356809, ENST00000546300, ENSP00000437576, ENST00000367838

HPA

ENSG00000143147-GPR161

PRO

Q8N6U8

Pharos - Targets

Q8N6U8

Orphanet

GPR161

GlyGen

Q8N6U8

PDB

8KH4, 8SMV

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P17612 PRKACA	4	PRKACA [cytosol] (R-HSA-57844) PRKACA [nucleoplasm] (R-HSA-111936) PRKACA [ciliary base] (R-HSA-5610402) PRKACA [mitochondrial matrix] (R-HSA-9838291)	0.643	4
UniProt:Q8N6F1-2 CLDN19			0.556	3
UniProt:O75841 UPK1B			0.556	3
UniProt:P52803 EFNA5	3	EFNA5 (21-?) N-ter [extracellular region] (R-HSA-3928456) EFNA5 (?-203) C-ter [plasma membrane] (R-HSA-3928431) EFNA5 [plasma membrane] (R-HSA-2682331)	0.556	3
UniProt:P21964 COMT	2	COMT [cytosol] (R-HSA-175974) COMT [plasma membrane] (R-HSA-379386)	0.556	3
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [endosome membrane] (R-HSA-435363) SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714)	0.556	3
UniProt:P10644 PRKAR1A	4	PRKAR1A [cytosol] (R-HSA-57836) PRKAR1A [ciliary base] (R-HSA-5610408) PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol] (R-HSA-9713471) PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9713476)	0.527	3
UniProt:P22612 PRKACG	3	PRKACG [ciliary base] (R-HSA-5610405) PRKACG [cytosol] (R-HSA-57848) PRKACG [nucleoplasm] (R-HSA-111938)	0.527	3
UniProt:O75317 USP12	1	USP12 [nucleoplasm] (R-HSA-5696907)	0.527	2
UniProt:P22694 PRKACB	3	PRKACB [ciliary base] (R-HSA-5610404) PRKACB [cytosol] (R-HSA-57846) PRKACB [nucleoplasm] (R-HSA-111937)	0.527	3
UniProt:P31321 PRKAR1B	2	PRKAR1B [cytosol] (R-HSA-57838) PRKAR1B [ciliary base] (R-HSA-5610409)	0.527	4
UniProt:Q8TBA6 GOLGA5	2	GOLGA5 [transport vesicle] (R-HSA-8847517) GOLGA5 [Golgi membrane] (R-HSA-8847514)	0.527	2

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