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GPR161 [endocytic vesicle membrane]
Stable Identifier
R-HSA-5635021
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endocytic vesicle membrane
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'on' state (Homo sapiens)
GPR161 is internalized (Homo sapiens)
GPR161 [endocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N6U8 GPR161
Gene Names
GPR161
Chain
chain:1-529
Reference Genes
BioGPS Gene:23432 GPR161
COSMIC (genes):GPR161 GPR161
CTD Gene:23432 GPR161
dbSNP Gene:23432 GPR161
ENSEMBL:ENSG00000143147 GPR161
ENSEMBL_homo_sapiens_GENE:ENSG00000143147.15 GPR161
HGNC:23694 GPR161
KEGG Gene (Homo sapiens):23432 GPR161
Monarch:23432 GPR161
NCBI Gene:23432 GPR161
OMIM:612250 GPR161
UCSC:Q8N6U8 GPR161
Reference Transcript
RefSeq:XM_005245056.2 GPR161
RefSeq:XM_011509378.1 GPR161
RefSeq:NM_001267612.1 GPR161
RefSeq:NM_001267610.1 GPR161
RefSeq:XM_005245055.2 GPR161
RefSeq:XM_011509377.1 GPR161
RefSeq:XM_011509376.2 GPR161
RefSeq:XM_017000862.1 GPR161
RefSeq:NM_153832.2 GPR161
RefSeq:XM_011509375.2 GPR161
RefSeq:XM_017000861.1 GPR161
RefSeq:XM_017000860.1 GPR161
RefSeq:NM_001267609.1 GPR161
RefSeq:NM_001267614.1 GPR161
RefSeq:NM_001267613.1 GPR161
RefSeq:XM_005245057.4 GPR161
RefSeq:XM_017000859.1 GPR161
Other Identifiers
11742775_a_at
11742776_s_at
11749295_a_at
16696073
206971_PM_at
206971_at
206972_PM_s_at
206972_s_at
214104_PM_at
214104_at
230369_PM_at
230369_at
232350_3p_x_at
232350_PM_x_at
232350_x_at
23432
235961_PM_at
235961_at
2442913
2442914
2442915
2442916
2442917
2442918
2442919
2442920
2442921
2442922
2442924
2442931
2442932
2442939
2442946
2442947
2442948
2442949
2442952
2442957
2442958
2442960
2442961
2442962
2442963
2442964
2442965
2442966
40300_g_at
40301_at
48259_at
55977_at
77927_i_at
77929_r_at
7922108
A_23_P103532
A_23_P303455
A_23_P354314
A_32_P497742
GE81746
GO:0004930
GO:0005515
GO:0005768
GO:0005886
GO:0005929
GO:0007165
GO:0007186
GO:0007189
GO:0016020
GO:0023052
GO:0030666
GO:0031410
GO:0042995
GO:0043005
GO:0043226
GO:0048856
GO:0055037
GO:0060089
GO:0060170
GO:0097386
GO:1901621
HMNXSV003049054
Hs.21606.0.A1_3p_at
Hs.271809.0.S1_3p_x_at
Hs.301642.1.S1_3p_at
Hs.85893.0.A1_3p_at
ILMN_1658586
ILMN_1773940
PH_hs_0023354
PH_hs_0039137
TC01005921.hg
g6677700_3p_a_at
g6677700_3p_x_at
Participates
as an output of
GPR161 is internalized (Homo sapiens)
Other forms of this molecule
GPR161 [ciliary membrane]
Inferred To
GPR161 [endocytic vesicle membrane]
(Bos taurus)
GPR161 [endocytic vesicle membrane]
(Canis familiaris)
GPR161 [endocytic vesicle membrane]
(Gallus gallus)
GPR161 [endocytic vesicle membrane]
(Sus scrofa)
Gpr161 [endocytic vesicle membrane]
(Mus musculus)
Gpr161 [endocytic vesicle membrane]
(Rattus norvegicus)
gpr161 [endocytic vesicle membrane]
(Danio rerio)
gpr161 [endocytic vesicle membrane]
(Xenopus tropicalis)
Cross References
RefSeq
XP_016856348.1
,
XP_011507678.1
,
NP_001254542.1
,
NP_722561.1
,
XP_016856351.1
,
XP_011507677.1
,
XP_005245113.1
,
NP_001254543.1
,
XP_016856350.1
,
XP_005245114.1
,
XP_005245112.1
,
XP_016856349.1
,
NP_001254539.1
,
NP_001254541.1
,
XP_011507679.1
,
XP_011507680.1
,
NP_001254538.1
Guide to Pharmacology - Targets
141
OpenTargets
ENSG00000143147
HPA
ENSG00000143147-GPR161
GeneCards
Q8N6U8
Ensembl
ENST00000537209
,
ENSP00000356809
,
ENST00000546300
,
ENSP00000506967
,
ENST00000367838
,
ENSP00000437576
,
ENSG00000143147
,
ENST00000367836
,
ENST00000367835
,
ENSP00000441039
,
ENSP00000444348
,
ENSP00000356810
,
ENSP00000356812
,
ENST00000539777
,
ENST00000682931
PRO
Q8N6U8
Pharos - Targets
Q8N6U8
Orphanet
23218
PDB
8SMV
,
8KH4
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17612 PRKACA
4
PRKACA [mitochondrial matrix]
(R-HSA-9838291)
PRKACA [ciliary base]
(R-HSA-5610402)
PRKACA [nucleoplasm]
(R-HSA-111936)
PRKACA [cytosol]
(R-HSA-57844)
0.643
4
UniProt:P52803 EFNA5
3
EFNA5 (21-?) N-ter [extracellular region]
(R-HSA-3928456)
EFNA5 (?-203) C-ter [plasma membrane]
(R-HSA-3928431)
EFNA5 [plasma membrane]
(R-HSA-2682331)
0.556
3
UniProt:O75841 UPK1B
0.556
3
UniProt:Q8N6F1-2 CLDN19
0.556
3
UniProt:P21964 COMT
2
COMT [plasma membrane]
(R-HSA-379386)
COMT [cytosol]
(R-HSA-175974)
0.556
3
UniProt:Q9BRI3 SLC30A2
2
SLC30A2 [endosome membrane]
(R-HSA-435363)
SLC30A2 [synaptic vesicle membrane]
(R-HSA-4084714)
0.556
3
UniProt:Q8TBA6 GOLGA5
2
GOLGA5 [transport vesicle]
(R-HSA-8847517)
GOLGA5 [Golgi membrane]
(R-HSA-8847514)
0.527
2
UniProt:P31321 PRKAR1B
2
PRKAR1B [cytosol]
(R-HSA-57838)
PRKAR1B [ciliary base]
(R-HSA-5610409)
0.527
4
UniProt:P22694 PRKACB
3
PRKACB [ciliary base]
(R-HSA-5610404)
PRKACB [cytosol]
(R-HSA-57846)
PRKACB [nucleoplasm]
(R-HSA-111937)
0.527
3
UniProt:O75317 USP12
1
USP12 [nucleoplasm]
(R-HSA-5696907)
0.527
2
UniProt:P22612 PRKACG
3
PRKACG [ciliary base]
(R-HSA-5610405)
PRKACG [cytosol]
(R-HSA-57848)
PRKACG [nucleoplasm]
(R-HSA-111938)
0.527
3
UniProt:P10644 PRKAR1A
4
PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713476)
PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713471)
PRKAR1A [ciliary base]
(R-HSA-5610408)
PRKAR1A [cytosol]
(R-HSA-57836)
0.527
3
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