polySUMO2-K467,K497-NOP58 [nucleoplasm]

Stable Identifier
R-HSA-4570460
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Nucleolar protein 58, NOP58_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
24782567 Proteome-wide identification of SUMO2 modification sites

Tatham, MH, Hay, RT, Tammsalu, T, Ibrahim, AF, Jaffray, EG, Matic, I

Sci Signal 2014
20797634 Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif

van Dam, H, van de Rijke, F, Hendriks, IA, Vertegaal, AC, Schimmel, J, Matic, I, Gnad, F, van Santen, MA, Mann, M

Mol. Cell 2010
25218447 Uncovering global SUMOylation signaling networks in a site-specific manner

Yang, B, Hendriks, IA, Verlaan-de Vries, M, Vertegaal, AC, D'Souza, RC, Mann, M

Nat. Struct. Mol. Biol. 2014
20797632 A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58

Lam, YW, Lamond, AI, Bertrand, E, Westman, BJ, Verheggen, C, Hutten, S

Mol. Cell 2010
25114211 Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

Impens, F, Cossart, P, Radoshevich, L, Ribet, D

Proc. Natl. Acad. Sci. U.S.A. 2014
21647297 A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics

Lamond, AI, Westman, BJ

Nucleus 2011
External Reference Information
External Reference
UniProt:Q9Y2X3 NOP58
Gene Names
NOP58, NOL5, NOP5, HSPC120
Chain
chain:1-529
Reference Genes
BioGPS Gene:51602 NOP58
COSMIC (genes):NOP58 NOP58
CTD Gene:51602 NOP58
dbSNP Gene:51602 NOP58
ENSEMBL:ENSG00000055044 NOP58
HGNC:29926 NOP58
KEGG Gene (Homo sapiens):51602 NOP58
Monarch:51602 NOP58
NCBI Gene:51602 NOP58
OMIM:616742 NOP58
UCSC:Q9Y2X3 NOP58
Reference Transcript
Other Identifiers
0001980128
11744098_at
11747090_a_at
16889602
223096_at
2523151
2523152
2523156
2523160
2523165
2523167
2523171
2523173
2523175
2523177
2523179
2523182
2523183
2523187
2523192
2523193
2523195
51602
53711_at
8047518
A_14_P110681
A_14_P202147
A_23_P154447
GE60555
GO:0001094
GO:0001650
GO:0003674
GO:0003723
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005730
GO:0005732
GO:0005737
GO:0005829
GO:0006364
GO:0008134
GO:0008150
GO:0015030
GO:0016020
GO:0019899
GO:0030515
GO:0031428
GO:0032040
GO:0032991
GO:0034641
GO:0042254
GO:0043226
GO:0048254
GO:0051117
GO:0070761
HMNXSV003015704
ILMN_1748476
PH_hs_0006617
TC02001188.hg
g6841461_3p_at
Participates
as an output of
Other forms of this molecule
monoSUMO1-K467,K497-NOP58 [nucleoplasm]
NOP58 [nucleoplasm]
Inferred To
polySUMO2-K467,K497-NOP58 [nucleoplasm] (Plasmodium falciparum)
nop5 [nucleoplasm] (Drosophila melanogaster)
nop58 [nucleoplasm] (Danio rerio)
nop58 [nucleoplasm] (Dictyostelium discoideum)
Nop58 [nucleoplasm] (Mus musculus)
Nop58 [nucleoplasm] (Rattus norvegicus)
NOP58 [nucleoplasm] (Gallus gallus)
Modified Residues
Name
sumoylated lysine (polySUMO2 [nucleoplasm]) at 467
Coordinate
467
Modification
polySUMO2 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO2 [nucleoplasm]) at 497
Coordinate
497
Modification
polySUMO2 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
GlyGen
PDB
Interactors (5)
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