Reactome | p-PELI2 [cytosol]

p-PELI2 [cytosol]

Stable Identifier

R-HSA-450825

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p-Pellino-2, Protein pellino homolog 2, PELI2, PELI2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HAT8 PELI2

Gene Names

PELI2

Chain

chain:1-420

Reference Genes

BioGPS Gene:57161 PELI2

COSMIC (genes):PELI2 PELI2

CTD Gene:57161 PELI2

dbSNP Gene:57161 PELI2

ENSEMBL:ENSG00000139946 PELI2

ENSEMBL:ENSG00000139946.11 PELI2

HGNC:8828 PELI2

KEGG Gene (Homo sapiens):57161 PELI2

Monarch:57161 PELI2

NCBI Gene:57161 PELI2

OMIM:614798 PELI2

UCSC:Q9HAT8 PELI2

Reference Transcript

RefSeq:NM_021255.2 PELI2

Other Identifiers

11724068_at

11724069_at

16784498

219132_PM_at

219132_at

3537165

3537166

3537167

3537181

3537201

3537204

3537206

3537209

3537210

3537211

3537212

57161

62136_at

7974533

A_14_P139723

A_23_P65532

GE56634

GO:0000209

GO:0001934

GO:0003824

GO:0005515

GO:0005829

GO:0008592

GO:0016567

GO:0016740

GO:0023052

GO:0034450

GO:0036211

GO:0043123

GO:0043410

GO:0061630

GO:0140096

HMNXSV003020289

HMNXSV003038369

ILMN_1780132

PH_hs_0003194

TC14000332.hg

g10864062_3p_at

Participates

as a member of

p-Pellino-1,2,(3) [cytosol] (Homo sapiens)

Other forms of this molecule

PELI2 [cytosol]

Inferred To

phospho-p-PELI2 [cytosol] (Canis familiaris)

phospho-PELI2 [cytosol] (Bos taurus)

phospho-PELI2 [cytosol] (Gallus gallus)

phospho-PELI2 [cytosol] (Sus scrofa)

phospho-Peli2 [cytosol] (Mus musculus)

phospho-Peli2 [cytosol] (Rattus norvegicus)

phospho-Pli [cytosol] (Drosophila melanogaster)

phospho-peli-1 [cytosol] (Caenorhabditis elegans)

phospho-peli2 [cytosol] (Xenopus tropicalis)

phospho-zgc:92268 [cytosol] (Danio rerio)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_067078.1

OpenTargets

ENSG00000139946

IntEnz

2.3.2.27

GeneCards

Q9HAT8

HPA

ENSG00000139946-PELI2

Ensembl

ENST00000267460, ENSP00000267460, ENSG00000139946

PRO

Q9HAT8

Pharos - Targets

Q9HAT8

PDB

3EGA, 3EGB

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P51617 IRAK1	14	p-S376,T387-IRAK1 [cytosol] (R-HSA-446687) K63polyUb-hp-IRAK1 [endosome membrane] (R-HSA-975112) p-S,T-IRAK1 [cytosol] (R-HSA-3149574) K63polyUb-hp-IRAK1 [cytosol] (R-HSA-451565) p-T209-IRAK1 [endosome membrane] (R-HSA-975189) p-T209,T387-IRAK1 [endosome membrane] (R-HSA-975117) IRAK1 [endosome membrane] (R-HSA-975127) p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (R-HSA-975157) IRAK1 [plasma membrane] (R-HSA-937045) p-T209-IRAK1 [plasma membrane] (R-HSA-937031) p-T209,T387-IRAK1 [plasma membrane] (R-HSA-166279) p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (R-HSA-937011) p-2S,S376,T,T209,T387-IRAK1 [cytosol] (R-HSA-446682) IRAK1 [cytosol] (R-HSA-446639)	0.743	4
UniProt:Q9NWZ3 IRAK4	9	IRAK4 R12C [cytosol] (R-HSA-5602511) IRAK4 Q293TER [cytosol] (R-HSA-5602426) IRAK4 E402TER [cytosol] (R-HSA-5602517) p-T342,T345,S346-IRAK4 [cytosol] (R-HSA-446649) IRAK4 [endosome membrane] (R-HSA-975167) p-T342,T345,S346-IRAK4 [endosome membrane] (R-HSA-975149) IRAK4 [plasma membrane] (R-HSA-937051) p-T342,T345,S346-IRAK4 [plasma membrane] (R-HSA-936957) IRAK4 [cytosol] (R-HSA-166081)	0.593	3
UniProt:Q12891 HYAL2	1	HYAL2 [plasma membrane] (R-HSA-2160919)	0.556	3
UniProt:P35227 PCGF2	1	PCGF2 [nucleoplasm] (R-HSA-389115)	0.556	3

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