Reactome | MEF2D [nucleoplasm]

MEF2D [nucleoplasm]

Stable Identifier

R-HSA-445328

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Myocyte-specific enhancer factor 2D, MEF2D_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14814 MEF2D

Gene Names

MEF2D

Chain

chain:1-521

Reference Genes

BioGPS Gene:4209 MEF2D

COSMIC (genes):MEF2D MEF2D

CTD Gene:4209 MEF2D

dbSNP Gene:4209 MEF2D

ENSEMBL:ENSG00000116604 MEF2D

HGNC:6997 MEF2D

KEGG:hsa:4209 MEF2D

Monarch:4209 MEF2D

NCBI Gene:4209 MEF2D

OMIM:600663 MEF2D

UCSC:Q14814 MEF2D

Reference Transcript

Other Identifiers

11717185_a_at

11717186_a_at

11717187_x_at

11749473_a_at

11752497_a_at

11755149_x_at

16694593

203003_PM_at

203003_at

203004_PM_s_at

203004_s_at

225641_PM_at

225641_at

2438218

2438219

2438220

2438221

2438222

2438225

2438226

2438227

2438228

2438229

2438230

2438233

2438234

2438235

2438236

2438239

2438240

2438241

2438242

2438243

2438244

2438245

2438246

2438247

2438248

2438251

2438252

2438253

2438254

2438255

2438256

2438258

2438259

2438260

2438261

2438262

35434_at

4209

54969_at

56968_at

7921014

88219_at

A_23_P334186

A_23_P51679

A_33_P3341656

GE57650

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006915

GO:0007399

GO:0007512

GO:0007517

GO:0030154

GO:0042826

GO:0045944

GO:0046983

GO:0048513

GO:0048856

GO:0061629

GO:0140297

GO:1904707

GO:1990837

HMNXSV003017099

HMNXSV003020351

Hs.111243.0.A2_3p_at

Hs.111243.0.A2_3p_x_at

Hs.77955.0.S1_3p_at

ILMN_1763228

PH_hs_0004501

TC01003341.hg

TC01005861.hg

g5174544_3p_a_at

Participates

as a candidate of

as an input of

p-S133 CREB1, MEF2D and SRF bind the ARC gene (Homo sapiens)

as a component of

p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm] (Homo sapiens)

as a member of

MEF2C,D [nucleoplasm] (Homo sapiens)

Inferred To

SMP1 [nucleoplasm] (Saccharomyces cerevisiae)

pvg4 [nucleoplasm] (Schizosaccharomyces pombe)

mef2A [nucleoplasm] (Dictyostelium discoideum)

Mef2d [nucleoplasm] (Mus musculus)

Mef2d [nucleoplasm] (Rattus norvegicus)

mbx1 [nucleoplasm] (Schizosaccharomyces pombe)

srfD [nucleoplasm] (Dictyostelium discoideum)

Homologues of MEF2D [nucleoplasm] (Dictyostelium discoideum)

Homologues of MEF2D [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of MEF2D [nucleoplasm] (Schizosaccharomyces pombe)

MEF2D [nucleoplasm] (Sus scrofa)

RLM1 [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

XP_054188819.1, XP_054188817.1, XP_047276949.1, XP_054188818.1, XP_054188827.1, XP_054188825.1, XP_054188826.1, XP_054188824.1, NP_001258558.1, XP_054188823.1, XP_054188821.1, XP_054188820.1, XP_054188822.1, XP_006711397.1, XP_016856804.1, XP_011507871.1, XP_006711393.1, XP_006711396.1, XP_005245227.1, XP_006711395.1, XP_005245226.1, XP_016856803.1, XP_047276954.1, XP_047276958.1, XP_054192638.1, XP_047276953.1, XP_054192633.1, XP_054192637.1, XP_047276955.1, XP_047276951.1, XP_047276950.1, XP_054192634.1, XP_047276961.1, XP_054192630.1, XP_054192629.1, XP_054192628.1, NP_005911.1, XP_054192627.1, XP_054192632.1, XP_054188816.1, XP_047276965.1, XP_054192636.1, XP_047276960.1, XP_054192631.1, XP_054192635.1

OpenTargets

ENSG00000116604

ENSEMBL

ENSP00000517291, ENSP00000517293, ENST00000360595, ENSP00000271555, ENSG00000291761, ENSG00000116604, ENST00000464356, ENSP00000517292, ENST00000708596, ENST00000708597, ENSP00000353803, ENSP00000476788, ENST00000708595, ENST00000348159

HPA

ENSG00000116604-MEF2D

GeneCards

MEF2D

PRO

Q14814

Pharos - Targets

Q14814

GlyGen

Q14814

PDB

8C84, 7X1N

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P68255	1	Ywhaq [cytosol] (R-RNO-1445116)	0.593	3
UniProt:Q16539 MAPK14	7	p-T180,Y182-MAPK14 [nucleoplasm] (R-HSA-446227) p-T180,Y182-MAPK14 [cytosol] (R-HSA-428935) MAPK14 [cytosol] (R-HSA-428933) MAPK14 [nucleoplasm] (R-HSA-446223) MAPK14 [secretory granule lumen] (R-HSA-6803300) MAPK14 [extracellular region] (R-HSA-6806453) MAPK14 [ficolin-1-rich granule lumen] (R-HSA-6803280)	0.547	2
UniProt:Q02078 MEF2A	3	MEF2A [nucleoplasm] (R-HSA-199903) p-S408-MEF2A [nucleoplasm] (R-HSA-199909) p-T312,T319-MEF2A [nucleoplasm] (R-HSA-448834)	0.527	3
UniProt:Q9BUR4 WRAP53	2	WRAP53 [nucleoplasm] (R-HSA-418386) Unfolded WRAP53 [cytosol] (R-HSA-6813830)	0.527	3
UniProt:Q9Z2V6	1	Hdac5 [nucleoplasm] (R-MMU-3004533)	0.488	2

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