Reactome | NCAM1 interactions

NCAM1 interactions

Stable Identifier

R-HSA-419037

Type

Pathway

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

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The neural cell adhesion molecule, NCAM1 is generally considered as a cell adhesion mediator, but it is also considered to be a signal transducing receptor molecule. NCAM1 is involved in multiple cis- and trans-homophilic interactions. It is also involved in several heterophilic interactions with a broad range of other molecules, thereby modulating diverse biological phenomena including cellular adhesion, migration, proliferation, differentiation, survival and synaptic plasticity.

Literature References

PubMed ID	Title	Journal	Year
15662836	Zippers make signals: NCAM-mediated molecular interactions and signal transduction Walmod, PS, Kolkova, K, Berezin, V, Bock, E	Neurochem Res	2004
20017013	Extracellular protein interactions mediated by the neural cell adhesion molecule, NCAM: heterophilic interactions between NCAM and cell adhesion molecules, extracellular matrix proteins, and viruses Nielsen, J, Kulahin, N, Walmod, PS	Adv Exp Med Biol	2010