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NCAM1 interacts with T- and L-type VDCC
Stable Identifier
R-HSA-525833
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
NCAM signaling for neurite out-growth (Homo sapiens)
NCAM1 interactions (Homo sapiens)
NCAM1 interacts with T- and L-type VDCC (Homo sapiens)
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NCAM1 associates with T- and L-type voltage-dependent Ca+2 channels (VDCC) in growthcones at the sites of NCAM1 clustering. This interaction leads to the NCAM-dependent Ca+2 influx to the cell.
Participants
Input
NCAM1:NCAM1 trans-homotetramer [plasma membrane]
(Homo sapiens)
T- and L-type VDCC [plasma membrane]
(Homo sapiens)
Output
NCAM1:T- and L-type VDCC [plasma membrane]
(Homo sapiens)
Participates
as an event of
NCAM1 interactions (Homo sapiens)
Inferred From
NCAM1 interacts with T- and L-type VDCC (Mus musculus)
Authored
Garapati, P V (2009-05-30)
Reviewed
Walmod, PS (2009-05-26)
Maness, PF (2009-05-26)
Created
Garapati, P V (2010-02-22)
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