Interaction of NCAM1 with Neurocan

Stable Identifier
R-HSA-375148
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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NCAM1 bind all major components of neurocan (N-terminal, central and C-terminal regions as well as CS chains), a brain-specific chondroitin sulfate proteoglycan. This molecule interferes with homophilic NCAM1 interactions and inhibits neuronal adhesion and neurite outgrowth.

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