Interaction of NCAM1 with Neurocan

Stable Identifier
R-HSA-375148
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
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Interaction of NCAM1 with Neurocan
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NCAM1 bind all major components of neurocan (N-terminal, central and C-terminal regions as well as CS chains), a brain-specific chondroitin sulfate proteoglycan. This molecule interferes with homophilic NCAM1 interactions and inhibits neuronal adhesion and neurite outgrowth.

Participants
Input
Output
Participant Of
hasEvent
Inferred From
Interaction of NCAM-1 with Neurocan (Rattus norvegicus)
Authored
Garapati, P V  (2009-02-24)
Reviewed
Maness, PF  (2009-05-26)
Walmod, PS  (2009-05-26)
Created
Garapati, P V  (2008-08-11)