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DPP4(39-766) [extracellular region]
Stable Identifier
R-HSA-400517
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Dipeptidyl peptidase 4, soluble form, DPP4, DPP4_HUMAN, alternativeName: Dipeptidyl peptidase IV, shortName:DPP IV, alternativeName: T-cell activation antigen CD26, alternativeName: TP103, alternativeName: Adenosine deaminase complexing protein 2, alternativeName: ADABP CdAntigenNameCD26/CdAntigenName component, recommendedName: Dipeptidyl peptidase 4 soluble form, alternativeName: Dipeptidyl peptidase IV soluble form /component
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Incretin synthesis, secretion, and inactivation (Homo sapiens)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Homo sapiens)
DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Homo sapiens)
DPP4(39-766) [extracellular region] (Homo sapiens)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Homo sapiens)
DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Homo sapiens)
DPP4(39-766) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27487 DPP4
Gene Names
DPP4, ADCP2, CD26
Chain
chain:1-766, chain:39-766
Reference Genes
BioGPS Gene:1803 DPP4
COSMIC (genes):DPP4 DPP4
CTD Gene:1803 DPP4
dbSNP Gene:1803 DPP4
ENSEMBL:ENSG00000197635 DPP4
HGNC:3009 DPP4
KEGG Gene (Homo sapiens):1803 DPP4
Monarch:1803 DPP4
NCBI Gene:1803 DPP4
OMIM:102720 DPP4
UCSC:P27487 DPP4
Reference Transcript
RefSeq:NM_001935.3 DPP4
Other Identifiers
0007040408
11756706_a_at
11758194_s_at
16904278
1803
203716_s_at
203717_at
211478_s_at
2584023
2584024
2584025
2584026
2584027
2584029
2584039
2584041
2584042
2584043
2584044
2584045
2584046
2584048
2584049
2584052
2584053
2584054
2584055
2584057
2584058
2584064
2584066
2584067
2584068
2584069
2584070
2584072
2584074
2584075
2584082
2584086
34823_at
8056222
A_24_P97104
A_33_P3287223
GE59864
GO:0001618
GO:0001662
GO:0001666
GO:0002020
GO:0002376
GO:0003674
GO:0004177
GO:0004252
GO:0005102
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005886
GO:0005925
GO:0006508
GO:0006810
GO:0006950
GO:0007155
GO:0007267
GO:0008150
GO:0008233
GO:0008236
GO:0008239
GO:0008283
GO:0008284
GO:0009986
GO:0010716
GO:0015031
GO:0016020
GO:0016021
GO:0016324
GO:0016787
GO:0019899
GO:0030027
GO:0030054
GO:0030139
GO:0030198
GO:0031258
GO:0031295
GO:0031410
GO:0033632
GO:0035641
GO:0036343
GO:0040011
GO:0042110
GO:0042802
GO:0042803
GO:0042995
GO:0043226
GO:0043542
GO:0044403
GO:0045121
GO:0045499
GO:0046581
GO:0046718
GO:0048870
GO:0050796
GO:0050919
GO:0070062
GO:0090024
HMNXSV003021959
ILMN_1692535
PH_hs_0003256
TC02002478.hg
X60708_at
g180082_3p_a_at
g180082_3p_x_at
g181569_3p_a_at
g4503366_3p_at
Other forms of this molecule
DPP4(1-766) [plasma membrane]
Inferred To
DPP4 [extracellular region]
(Canis familiaris)
DPP4 [extracellular region]
(Gallus gallus)
fap [extracellular region]
(Danio rerio)
fap [extracellular region]
(Xenopus tropicalis)
Dpp4 [extracellular region]
(Mus musculus)
Dpp4 [extracellular region]
(Rattus norvegicus)
Cross References
RefSeq
NP_001926.2
ZINC - World Drugs
DPP4_HUMAN
Guide to Pharmacology - Targets
1612
OpenTargets
ENSG00000197635
ZINC - FDA approved
DPP4_HUMAN
ZINC - Substances
DPP4_HUMAN
ZINC target
P27487
ZINC - Biogenic
DPP4_HUMAN
PRO
P27487
GlyGen
P27487
PDB
5Y7H
,
3QBJ
,
2IIV
,
2HHA
,
2OQI
,
2OAG
,
2QKY
,
3KWJ
,
4J3J
,
1X70
,
2QTB
,
2RIP
,
2G5P
,
3C43
,
3H0C
,
1RWQ
,
4A5S
,
2OLE
,
5T4E
,
3C45
,
2OPH
,
3KWF
,
2AJL
,
4G1F
,
3Q8W
,
2I03
,
1WCY
,
5T4B
,
4KR0
,
4DTC
,
2BGR
,
2QOE
,
2OGZ
,
3CCB
,
2I78
,
3W2T
,
4DSA
,
2RGU
,
1R9N
,
3G0G
,
2ONC
,
1W1I
,
3G0B
,
3EIO
,
5Y7J
,
4N8E
,
4QZV
,
2G5T
,
2IIT
,
2G63
,
2BUB
,
5ZID
,
3HAC
,
3HAB
,
1NU6
,
6B1O
,
1TKR
,
3OC0
,
1NU8
,
1U8E
,
5T4H
,
4JH0
,
3O9V
,
3BJM
,
4PNZ
,
4L72
,
2QT9
,
3WQH
,
5T4F
,
6B1E
,
4LKO
,
3F8S
,
2P8S
,
3CCC
,
1TK3
,
4DSZ
,
3VJM
,
5ISM
,
2BGN
,
3Q0T
,
5KBY
,
2FJP
,
2QJR
,
3O95
,
3VJL
,
3D4L
,
1PFQ
,
3NOX
,
3VJK
,
1N1M
,
5J3J
,
1R9M
,
2JID
,
5I7U
,
1J2E
,
4PV7
,
3OPM
,
3G0C
,
3SX4
,
3SWW
,
3G0D
,
5Y7K
,
4N8D
,
2OQV
ZINC - Investigational
DPP4_HUMAN
HPA
ENSG00000197635-DPP4
GeneCards
P27487
Ensembl
ENSG00000197635
,
ENST00000360534
,
ENSP00000353731
Pharos - Targets
P27487
ZINC - Predictions - Purchasable
DPP4_HUMAN
HMDB Protein
HMDBP01651
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:K9N5Q8 SPIKE
0.842
7
UniProt:K0BRG7 K0BRG7
0.74
5
UniProt:P19875 CXCL2
1
CXCL2(35-107) [extracellular region]
(R-HSA-373777)
0.623
2
UniProt:P51671 CCL11
1
CCL11 [extracellular region]
(R-HSA-443966)
0.623
2
UniProt:O14625 CXCL11
1
CXCL11 [extracellular region]
(R-HSA-373852)
0.623
2
UniProt:P02778 CXCL10
1
CXCL10(22-98) [extracellular region]
(R-HSA-373853)
0.623
2
UniProt:Q07325 CXCL9
1
CXCL9 [extracellular region]
(R-HSA-373856)
0.623
2
UniProt:P27487 DPP4
2
DPP4(39-766) [extracellular region]
(R-HSA-400517)
DPP4(1-766) [plasma membrane]
(R-HSA-400527)
0.611
12
UniProt:R9UQ53 R9UQ53
0.602
3
UniProt:A0A2R4KP93 A0A2R4KP93
0.558
2
UniProt:Q14416 GRM2
1
GRM2 [plasma membrane]
(R-HSA-420468)
0.524
2
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