Reactome | DPP4(39-766) [extracellular region]

DPP4(39-766) [extracellular region]

Stable Identifier

R-HSA-400517

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Dipeptidyl peptidase 4, soluble form, DPP4, DPP4_HUMAN, alternativeName: Dipeptidyl peptidase IV, shortName:DPP IV, alternativeName: T-cell activation antigen CD26, alternativeName: TP103, alternativeName: Adenosine deaminase complexing protein 2, alternativeName: ADABP CdAntigenNameCD26/CdAntigenName component, recommendedName: Dipeptidyl peptidase 4 soluble form, alternativeName: Dipeptidyl peptidase IV soluble form /component

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External Reference Information

External Reference

UniProt:P27487 DPP4

Gene Names

DPP4, ADCP2, CD26

Chain

chain:1-766, chain:39-766

Reference Genes

BioGPS Gene:1803 DPP4

COSMIC (genes):DPP4 DPP4

CTD Gene:1803 DPP4

dbSNP Gene:1803 DPP4

ENSEMBL:ENSG00000197635 DPP4

HGNC:3009 DPP4

KEGG Gene (Homo sapiens):1803 DPP4

Monarch:1803 DPP4

NCBI Gene:1803 DPP4

OMIM:102720 DPP4

UCSC:P27487 DPP4

Reference Transcript

RefSeq:NM_001935.3 DPP4

Other Identifiers

0007040408

11756706_a_at

11758194_s_at

16904278

1803

1J2E

1N1M

1NU6

1NU8

1PFQ

1R9M

1R9N

1RWQ

1TK3

1TKR

1U8E

1W1I

1WCY

1X70

203716_s_at

203717_at

211478_s_at

2584023

2584024

2584025

2584026

2584027

2584029

2584039

2584041

2584042

2584043

2584044

2584045

2584046

2584048

2584049

2584052

2584053

2584054

2584055

2584057

2584058

2584064

2584066

2584067

2584068

2584069

2584070

2584072

2584074

2584075

2584082

2584086

2AJL

2BGN

2BGR

2BUB

2FJP

2G5P

2G5T

2G63

2HHA

2I03

2I78

2IIT

2IIV

2JID

2OAG

2OGZ

2OLE

2ONC

2OPH

2OQI

2OQV

2P8S

2QJR

2QKY

2QOE

2QT9

2QTB

2RGU

2RIP

34823_at

3BJM

3C43

3C45

3CCB

3CCC

3D4L

3EIO

3F8S

3G0B

3G0C

3G0D

3G0G

3H0C

3HAB

3HAC

3KWF

3KWJ

3NOX

3O95

3O9V

3OC0

3OPM

3Q0T

3Q8W

3QBJ

3SWW

3SX4

3VJK

3VJL

3VJM

3W2T

3WQH

45970

4A5S

4DSA

4DSZ

4DTC

4G1F

4J3J

4JH0

4KR0

4L72

4LKO

4N8D

4N8E

4PNZ

4PV7

4QZV

5I7U

5ISM

5J3J

5KBY

5T4B

5T4E

5T4F

5T4H

5Y7H

5Y7J

5Y7K

5ZID

6B1E

6B1O

8056222

A_24_P97104

A_33_P3287223

AAA51943

AAA52308

AAB35614

AAB60646

AAH13329

AAH65265

AAX93179

AB451339

AB451488

AC008063

BAG70153

BAG70302

BC013329

BC065265

CAA43118

CAB045970

CCDS2216

CH471058

DPP4

DPP4-201

EAX11361

ENSG00000197635

ENSP00000353731

ENST00000360534

ENST00000360534.7

EntrezGene:1803

EntrezGene:DPP4

F8WBB6

F8WE17

g180082_3p_a_at

g180082_3p_x_at

g181569_3p_a_at

g4503366_3p_at

GE59864

GO:0001618

GO:0001662

GO:0001666

GO:0002020

GO:0002376

GO:0003674

GO:0004177

GO:0004252

GO:0005102

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005623

GO:0005737

GO:0005764

GO:0005765

GO:0005773

GO:0005886

GO:0005925

GO:0006508

GO:0006810

GO:0006950

GO:0007155

GO:0007267

GO:0008150

GO:0008233

GO:0008236

GO:0008239

GO:0008283

GO:0008284

GO:0009986

GO:0010716

GO:0015031

GO:0016020

GO:0016021

GO:0016324

GO:0016787

GO:0019899

GO:0030027

GO:0030054

GO:0030139

GO:0030198

GO:0031258

GO:0031295

GO:0031410

GO:0033632

GO:0035641

GO:0036343

GO:0040011

GO:0042110

GO:0042802

GO:0042803

GO:0042995

GO:0043226

GO:0043542

GO:0044403

GO:0045121

GO:0046581

GO:0046718

GO:0048870

GO:0050796

GO:0070062

GO:0071438

HGNC:3009

ILMN_1692535

IPR001375

IPR002469

IPR002471

IPR029058

IPR038554

M74777

M80536

MIM:102720

NM_001935

NP_001926

PF00326

PF00930

PH_hs_0003256

S79876

TC02002478.hg

U13710

U13711

U13712

U13713

U13714

U13715

U13716

U13717

U13718

U13719

U13720

U13721

U13722

U13723

U13724

U13725

U13726

U13727

U13728

U13729

U13730

U13731

U13732

U13733

U13734

U13735

UPI000004F7BF

X60708

X60708_at

XM_005246371

XP_005246428

Other forms of this molecule

DPP4(1-766) [plasma membrane]

Inferred To

DPP4(39-766) [extracellular region] (Bos taurus)

DPP4(39-766) [extracellular region] (Canis familiaris)

DPP4(39-766) [extracellular region] (Danio rerio)

DPP4(39-766) [extracellular region] (Gallus gallus)

DPP4(39-766) [extracellular region] (Mus musculus)

DPP4(39-766) [extracellular region] (Rattus norvegicus)

DPP4(39-766) [extracellular region] (Xenopus tropicalis)

Homologues of DPP4(39-766) [extracellular region] (Bos taurus)

Cross References

RefSeq

NP_001926.2

ZINC - World Drugs

DPP4_HUMAN

OpenTargets

ENSG00000197635

ZINC - FDA approved

DPP4_HUMAN

ZINC - Substances

DPP4_HUMAN

ZINC target

P27487

ZINC - Biogenic

DPP4_HUMAN

PRO

P27487

PDB

3D4L, 2QKY, 5KBY, 3WQH, 2OAG, 1W1I, 2QTB, 1R9N, 3C43, 5ISM, 4QZV, 2I78, 2OQI, 4DSZ, 2AJL, 2OPH, 3G0D, 2BGR, 3VJM, 3OC0, 2HHA, 4N8E, 2OLE, 3HAC, 5Y7J, 3W2T, 3O9V, 3Q0T, 2QOE, 2IIV, 3G0C, 1X70, 4DSA, 6B1O, 3KWF, 5ZID, 4PNZ, 6B1E, 3NOX, 3H0C, 2BGN, 2G5T, 4LKO, 1U8E, 3OPM, 5T4H, 4JH0, 3SWW, 4L72, 2RIP, 3C45, 3SX4, 2ONC, 3O95, 1TK3, 5T4F, 4A5S, 2BUB, 1NU8, 3CCB, 3QBJ, 4DTC, 4PV7, 5T4B, 1NU6, 3BJM, 3CCC, 2QT9, 4N8D, 2IIT, 3VJL, 2RGU, 2P8S, 1TKR, 2G63, 3G0G, 3KWJ, 3G0B, 3Q8W, 5Y7K, 3EIO, 3VJK, 5J3J, 1WCY, 3HAB, 5Y7H, 1RWQ, 1J2E, 2QJR, 1PFQ, 1R9M, 2OGZ, 2G5P, 2FJP, 4J3J, 2OQV, 2JID, 5T4E, 1N1M, 3F8S, 5I7U, 4KR0, 2I03, 4G1F

ZINC - Investigational

DPP4_HUMAN

GeneCards

P27487

ZINC - Predictions - Purchasable

DPP4_HUMAN

HMDB Protein

HMDBP01651

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:K0BRG7 K0BRG7			0.74	5
UniProt:P19875 CXCL2	1	CXCL2(35-107) [extracellular region] (R-HSA-373777)	0.623	2
UniProt:P51671 CCL11	1	CCL11 [extracellular region] (R-HSA-443966)	0.623	2
UniProt:O14625 CXCL11	1	CXCL11 [extracellular region] (R-HSA-373852)	0.623	2
UniProt:P02778 CXCL10	1	CXCL10(22-98) [extracellular region] (R-HSA-373853)	0.623	2
UniProt:Q07325 CXCL9	1	CXCL9 [extracellular region] (R-HSA-373856)	0.623	2
UniProt:P27487 DPP4	2	DPP4(1-766) [plasma membrane] (R-HSA-400527) DPP4(39-766) [extracellular region] (R-HSA-400517)	0.611	12