Reactome | Vasopressin-like receptors

Vasopressin-like receptors

Stable Identifier

R-HSA-388479

Type

Pathway

Species

Homo sapiens

ReviewStatus

5/5

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The vasopressins are peptide hormones consisting of nine amino acids (nonapeptides). They include arginine vasopressin (AVP; anti-diuretic hormone, ADH) and oxytocin. They are synthesized in the hypothalamus from a precursor and released from stores in the posterior pituitary into the blood stream. One of the most important roles of vasopressins is the regulation of water retention in the body. Oxytocin is important in uterine contraction during birth. The vasopressins act via AVP and oxytocin receptors. These are connected to G proteins which act as second messengers and convey the signal inside the cell.

Literature References

PubMed ID	Title	Journal	Year
8719042	Molecular neurobiology and pharmacology of the vasopressin/oxytocin receptor family Peter, J, Burbach, H, Adan, RA, Lolait, SJ, van Leeuwen, FW, Mezey, E, Palkovits, M, Barberis, C	Cell Mol Neurobiol	1995
8734452	Vasopressin and oxytocin receptors Zingg, HH	Baillieres Clin Endocrinol Metab	1996
11274341	The oxytocin receptor system: structure, function, and regulation Gimpl, G, Fahrenholz, F	Physiol Rev	2001