Oxytocin receptor bind oxytocin

Stable Identifier
R-HSA-388503
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Oxytocin is a nonapetide closely related to vasopressin (Mohr E et al, 1985; Sausville E et al, 1985). It is best known for its roles in female reproduction: it is released in large amounts during labour facilitating birth and afterwards, breastfeeding. It also acts as a neurotransmitter in the brain. The actions of oxytocin via the oxytocin receptor (Kimura T et al, 1992) are mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Literature References
PubMed ID Title Journal Year
2991279 The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line

Sausville, E, Carney, D, Battey, J

J Biol Chem 1985
1313946 Structure and expression of a human oxytocin receptor

Kimura, T, Tanizawa, O, Mori, K, Brownstein, MJ, Okayama, H

Nature 1992
4065330 Expression of the vasopressin and oxytocin genes in human hypothalami

Mohr, E, Hillers, M, Ivell, R, Haulica, ID, Richter, D

FEBS Lett 1985
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