Oxytocin receptor bind oxytocin

Stable Identifier
Reaction [binding]
Homo sapiens
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Oxytocin is a nonapetide closely related to vasopressin (Mohr E et al, 1985; Sausville E et al, 1985). It is best known for its roles in female reproduction: it is released in large amounts during labour facilitating birth and afterwards, breastfeeding. It also acts as a neurotransmitter in the brain. The actions of oxytocin via the oxytocin receptor (Kimura T et al, 1992) are mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Literature References
PubMed ID Title Journal Year
1313946 Structure and expression of a human oxytocin receptor

Mori, K, Kimura, T, Brownstein, MJ, Okayama, H, Tanizawa, O

Nature 1992
2991279 The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line

Carney, D, Battey, J, Sausville, E

J Biol Chem 1985
4065330 Expression of the vasopressin and oxytocin genes in human hypothalami

Richter, D, Ivell, R, Hillers, M, Haulica, ID, Mohr, E

FEBS Lett 1985
Orthologous Events
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