AVPR2 bind desmopressin

Stable Identifier
R-HSA-9667563
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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AVPR2 bind desmopressin
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Desmopressin (trade name DDAVP) is a vasopressin receptor agonist drug used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels. Desmopressin stimulates the release of von Willebrand factor from endothelial cells (Warrier & Lusher 1983, Santiago-Borrero & Casanova 1990) via arginine vasopressin receptor 2 (AVPR2) (Slusarz et al. 2006). Unlike vasopressin, desmopressin has little effect on blood pressure.
Literature References
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Output
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as an event of
Orthologous Events
AVPR2 bind desmopressin (Bos taurus)
AVPR2 bind desmopressin (Canis familiaris)
AVPR2 bind desmopressin (Danio rerio)
AVPR2 bind desmopressin (Mus musculus)
AVPR2 bind desmopressin (Rattus norvegicus)
AVPR2 bind desmopressin (Sus scrofa)
AVPR2 bind desmopressin (Xenopus tropicalis)
Authored
Jassal, B  (2021-03-25)
Reviewed
Huddart, R  (2022-03-01)
Created
Jassal, B  (2019-11-14)
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