Dopamine once taken up by the dopamine transporter from the extracellular space into the cytosol is metabolized in a two step reaction to homovanillic acid.The first reaction is catalyzed by catecholamine o-methyl transferase and the subsequent reaction is catalyzed by monoamine oxidase A.
Shabalina, SA, Maixner, W, Nackley, AG, Korchynskyi, O, Satterfield, K, Diatchenko, L, Tchivileva, IE, Makarov, SS
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