Dopamine clearance from the synaptic cleft

Stable Identifier
R-HSA-379401
Type
Pathway
Species
Homo sapiens
Synonyms
Clearance of dopamine
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Dopamine clearance from the synaptic cleft
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The human gene SLC6A3 encodes the sodium-dependent dopamine transporter, DAT which mediates the re-uptake of dopamine from the synaptic cleft (Vandenbergh DJ et al, 2000). Dopamine can then be degraded by either COMT or monoamine oxidase.

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Orthologous Events
Dopamine clearance from the synaptic cleft (Bos taurus)
Dopamine clearance from the synaptic cleft (Caenorhabditis elegans)
Dopamine clearance from the synaptic cleft (Canis familiaris)
Dopamine clearance from the synaptic cleft (Danio rerio)
Dopamine clearance from the synaptic cleft (Dictyostelium discoideum)
Dopamine clearance from the synaptic cleft (Drosophila melanogaster)
Dopamine clearance from the synaptic cleft (Gallus gallus)
Dopamine clearance from the synaptic cleft (Mus musculus)
Dopamine clearance from the synaptic cleft (Plasmodium falciparum)
Dopamine clearance from the synaptic cleft (Rattus norvegicus)
Dopamine clearance from the synaptic cleft (Schizosaccharomyces pombe)
Dopamine clearance from the synaptic cleft (Sus scrofa)
Dopamine clearance from the synaptic cleft (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Mahajan, SS  (2008-01-14)
Reviewed
Restituito, S  (2008-11-27)
Created
Mahajan, SS  (2008-10-17)
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