Reactome | POTEE [cytosol]

POTEE [cytosol]

Stable Identifier

R-HSA-9715126

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RHOF GTPase cycle (Homo sapiens)
        
        RHOF binds effectors at the plasma membrane (Homo sapiens)
        
        RHOF effectors [cytosol] (Homo sapiens)
        
        POTEE [cytosol] (Homo sapiens)
        
        RHOF:GTP:RHOF effectors [plasma membrane] (Homo sapiens)
        
        RHOF effectors [cytosol] (Homo sapiens)
        
        POTEE [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q6S8J3 POTEE

Gene Names

POTEE, A26C1A, POTE2

Chain

chain:1-1075

Reference Genes

BioGPS Gene:445582 POTEE

COSMIC (genes):POTEE POTEE

CTD Gene:445582 POTEE

dbSNP Gene:445582 POTEE

ENSEMBL:ENSG00000188219 POTEE

HGNC:33895 POTEE

Monarch:445582 POTEE

NCBI Gene:445582 POTEE

OMIM:608914 POTEE

UCSC:Q6S8J3 POTEE

Reference Transcript

Other Identifiers

11742182_x_at

11757100_s_at

16885596

16885685

16902703

2505610

2505611

2505683

2505684

2505687

2505690

2505692

2505704

2505706

2505708

2505712

2505714

2505716

2505720

2505722

2505994

2505995

2505997

2505998

2505999

2506000

2506001

2506002

2506003

2506004

2506005

2506006

2506007

2506011

2506012

2506015

2506016

2506017

2506018

2506019

2506020

2506021

2506022

2506023

2506024

2506025

2506057

2506058

2506065

2506068

2506072

2506073

2506078

2506082

2506084

2506087

2575783

2575785

2575787

2575789

2575793

2575794

2575796

2575799

2575800

2575803

2575807

2575808

2575809

2575811

2575815

2575817

2575819

2575820

2575821

2575822

2575824

2575863

2575865

2575869

2576043

2576046

2576048

2576052

2576054

2576056

2576058

2576060

2576061

2576062

2576064

2576066

2576067

2576068

2576071

2576072

2576073

2576074

2576075

2576076

2576080

2576081

2576082

2909059

3096654

3358997

3612786

3612789

3612792

3612793

3712504

3800392

3800394

3800398

3800399

3914570

3914573

3914576

3951307

3951311

3951312

3951316

3951322

3951329

3951331

3951333

445582

7977454

8045208

8045257

8045321

8055151

8055153

8055220

8055222

A_24_P357950

A_24_P410017

A_24_P825874

A_32_P9455

GO:0003674

GO:0005198

GO:0005515

GO:0005615

GO:0005737

GO:0005884

GO:0007010

GO:0007409

GO:0016020

GO:0019901

GO:0021762

GO:0030424

GO:0035267

GO:0043226

GO:0045202

GO:0048856

GO:0048870

GO:0070062

GO:0072562

GO:0098973

GO:0098974

HMNXSV003035539

HMNXSV003056079

ILMN_1735698

ILMN_1814643

ILMN_2370916

PH_hs_0035296

PH_hs_0038803

PH_hs_0039708

TC02000816.hg

TC02000830.hg

TC02002317.hg

TC02002339.hg

TC02004582.hg

g12408251_3p_s_at

Participates

as a candidate of

RHOF effectors [cytosol] (Homo sapiens)

Inferred To

Actg1 [cytosol] (Mus musculus)

Actg1 [cytosol] (Rattus norvegicus)

Act5C [cytosol] (Drosophila melanogaster)

ACTG1 [cytosol] (Bos taurus)

ACTG1 [cytosol] (Canis familiaris)

ACTG1 [cytosol] (Gallus gallus)

ACTG1 [cytosol] (Sus scrofa)

act-4 [cytosol] (Caenorhabditis elegans)

actb [cytosol] (Xenopus tropicalis)

act-2 [cytosol] (Caenorhabditis elegans)

Act42A [cytosol] (Drosophila melanogaster)

actbb [cytosol] (Danio rerio)

POTEE [cytosol] (Canis familiaris)

act-1 [cytosol] (Caenorhabditis elegans)

act-3 [cytosol] (Caenorhabditis elegans)

Homologues of POTEE [cytosol] (Caenorhabditis elegans)

Homologues of POTEE [cytosol] (Canis familiaris)

Homologues of POTEE [cytosol] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000358087, ENST00000356920, ENST00000514256, ENSP00000477649, ENSP00000485683, ENSP00000443049, ENSP00000507284, ENST00000626191, ENSP00000439189, ENST00000683005

OpenTargets

ENSG00000188219

HPA

ENSG00000188219-POTEE

PRO

Q6S8J3

Pharos - Targets

Q6S8J3

GlyGen

Q6S8J3

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P41597 CCR2	1	CCR2 [plasma membrane] (R-HSA-2976755)	0.589	2
UniProt:P09429 HMGB1	5	HC23,45-HMGB1 [extracellular region] (R-HSA-6797422) HMGB1 [nucleoplasm] (R-HSA-266221) HMGB1 [extracellular region] (R-HSA-879382) HMGB1 [secretory granule lumen] (R-HSA-6803337) HMGB1 [ficolin-1-rich granule lumen] (R-HSA-6803291)	0.527	2
UniProt:Q8NCH0 CHST14	9	CHST14 K69* [Golgi membrane] (R-HSA-3636891) CHST14 R135G [Golgi membrane] (R-HSA-3636924) CHST14 C289S [Golgi membrane] (R-HSA-3636925) CHST14 V49* [Golgi membrane] (R-HSA-3636926) CHST14 R213P [Golgi membrane] (R-HSA-3636894) CHST14 Y293C [Golgi membrane] (R-HSA-3636927) CHST14 P281L [Golgi membrane] (R-HSA-3636880) CHST14 L137Q [Golgi membrane] (R-HSA-5649488) CHST14 [Golgi membrane] (R-HSA-1971536)	0.527	2
UniProt:Q9HC97 GPR35	1	GPR35 [plasma membrane] (R-HSA-3295332)	0.527	2
UniProt:Q6UWB1 IL27RA	4	IL27RA [plasma membrane] (R-HSA-448478) p-Y611-IL27RA [plasma membrane] (R-HSA-8950330) sIL27RA [extracellular region] (R-HSA-8950454) sIL27RA [cytoplasm] (R-HSA-8950653)	0.527	2