Reactome | STAG2 [cytosol]

STAG2 [cytosol]

Stable Identifier

R-HSA-2484897

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

SA2, Cohesin subunit SA-2, SCC3 homolog 2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N3U4 STAG2

Gene Names

STAG2, SA2

Chain

chain:1-1231

Reference Genes

BioGPS Gene:10735 STAG2

COSMIC (genes):STAG2 STAG2

CTD Gene:10735 STAG2

dbSNP Gene:10735 STAG2

ENSEMBL:ENSG00000101972 STAG2

HGNC:11355 STAG2

KEGG:hsa:10735 STAG2

Monarch:10735 STAG2

NCBI Gene:10735 STAG2

OMIM:300826 STAG2

UCSC:Q8N3U4 STAG2

Reference Transcript

Participates

as a component of

Other forms of this molecule

STAG2 [nucleoplasm]

STAG2 [chromosome, centromeric region]

STAG2 [chromosome]

p-STAG2 [cytosol]

p-STAG2 [chromosome]

p-STAG2 [chromosome, centromeric region]

monoSUMO1-K-STAG2 [nucleoplasm]

Inferred To

SA2 [cytosol] (Drosophila melanogaster)

IRR1 [cytosol] (Saccharomyces cerevisiae)

Homologues of STAG2 [cytosol] (Drosophila melanogaster)

Homologues of STAG2 [cytosol] (Schizosaccharomyces pombe)

SA1 [cytosol] (Drosophila melanogaster)

scc-3 [cytosol] (Caenorhabditis elegans)

Stag2 [cytosol] (Mus musculus)

Stag2 [cytosol] (Rattus norvegicus)

rec11 [cytosol] (Schizosaccharomyces pombe)

STAG2 [cytosol] (Bos taurus)

STAG2 [cytosol] (Canis familiaris)

STAG2 [cytosol] (Dictyostelium discoideum)

STAG2 [cytosol] (Gallus gallus)

STAG2 [cytosol] (Sus scrofa)

psc3 [cytosol] (Schizosaccharomyces pombe)

stag2b [cytosol] (Danio rerio)

Cross References

RefSeq

NP_001269347.1, NP_001036214.1, XP_016884722.1, XP_016884721.1, XP_011529555.1, XP_005262415.1, XP_016884723.1, XP_005262417.1, NP_001036215.1, NP_001036216.1, XP_005262414.1, XP_005262416.1, XP_006724790.1, XP_005262418.1, NP_006594.3

OpenTargets

ENSG00000101972

ENSEMBL

ENSP00000360187, ENSP00000360186, ENSP00000360199, ENSP00000360202, ENSG00000101972, ENST00000218089, ENSP00000397265, ENSP00000509048, ENST00000687852, ENST00000371144, ENST00000455404, ENST00000371145, ENST00000371157, ENST00000371160, ENSP00000218089

HPA

ENSG00000101972-STAG2

GeneCards

STAG2

PRO

Q8N3U4

Pharos - Targets

Q8N3U4

Orphanet

STAG2

GlyGen

Q8N3U4

PDB

6QNX, 4PJU, 4PJW, 4PK7, 8K4D, 7ZJS

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60216 RAD21	14	RAD21 [nucleoplasm] (R-HSA-163042) RAD21 [chromosome, centromeric region] (R-HSA-2466012) RAD21 [chromosome] (R-HSA-1638775) p-S454-RAD21 [cytosol] (R-HSA-2500310) p-S454-RAD21 [chromosome] (R-HSA-2485164) p-S454-RAD21 [chromosome, centromeric region] (R-HSA-2485163) RAD21(1-172) [chromosome, centromeric region] (R-HSA-2467793) p-S454-RAD21(451-631) [chromosome, centromeric region] (R-HSA-2467790) RAD21(173-450) [chromosome, centromeric region] (R-HSA-2500296) RAD21(1-172) [cytosol] (R-HSA-2484901) RAD21(173-450) [cytosol] (R-HSA-2500308) p-S454-RAD21(451-631) [cytosol] (R-HSA-2500309) RAD21 [cytosol] (R-HSA-2484795) monoSUMO1-K-RAD21 [nucleoplasm] (R-HSA-3108183)	0.966	22
UniProt:Q7Z5K2 WAPL	4	WAPAL [cytosol] (R-HSA-2484802) WAPAL [chromosome] (R-HSA-2577090) WAPAL [chromosome, centromeric region] (R-HSA-2577088) WAPAL [nucleoplasm] (R-HSA-2466355)	0.922	14
UniProt:Q5FBB7 SGO1	3	SGOL1 [cytosol] (R-HSA-376227) SGO1 [nucleoplasm] (R-HSA-2468161) p-S-SGO1 [nucleoplasm] (R-HSA-9929718)	0.774	7
UniProt:Q9CPY3	6	phospho-Cdca5 [chromosome, centromeric region] (R-MMU-2468269) phospho-Cdca5 [cytosol] (R-MMU-2484804) phospho-Cdca5 [chromosome] (R-MMU-2468266) Cdca5 [chromosome] (R-MMU-2468149) Cdca5 [chromosome, centromeric region] (R-MMU-2468260) Cdca5 [nucleoplasm] (R-MMU-2466357)	0.669	3
UniProt:Q96FF9 CDCA5	6	p-S21,S75,T159-CDCA5 [chromosome, centromeric region] (R-HSA-2468269) p-S21,S75,T159-CDCA5 [cytosol] (R-HSA-2484804) p-S21,S75,T159-CDCA5 [chromosome] (R-HSA-2468266) CDCA5 [chromosome] (R-HSA-2468149) CDCA5 [chromosome, centromeric region] (R-HSA-2468260) CDCA5 [nucleoplasm] (R-HSA-2466357)	0.643	5
UniProt:Q9NP77 SSU72	1	SSU72 [nucleoplasm] (R-HSA-6814915)	0.577	4

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