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HES1 gene [nucleoplasm]
Stable Identifier
R-HSA-2197548
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells (Homo sapiens)
NOTCH1 stimulates HES1 transcription (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by NOTCH1 in Cancer (Homo sapiens)
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer (Homo sapiens)
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants (Homo sapiens)
NOTCH1 PEST domain mutants bind HES1 promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
Signaling by NOTCH1 PEST Domain Mutants in Cancer (Homo sapiens)
Constitutive Signaling by NOTCH1 PEST Domain Mutants (Homo sapiens)
NOTCH1 PEST domain mutants bind HES1 promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX3 (Homo sapiens)
RUNX3 regulates NOTCH signaling (Homo sapiens)
HES1 gene transcription is inhibited by RUNX3 (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex binds HES1 promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 stimulates HES1 transcription (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH1 (Homo sapiens)
NOTCH1 Intracellular Domain Regulates Transcription (Homo sapiens)
NOTCH1 Coactivator Complex binds HES1 promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 stimulates HES1 transcription (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
Signaling by NOTCH2 (Homo sapiens)
NOTCH2 intracellular domain regulates transcription (Homo sapiens)
NOTCH2 coactivator complex binds HES1 promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH2 stimulates HES1 transcription (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
Signaling by NOTCH3 (Homo sapiens)
NOTCH3 Intracellular Domain Regulates Transcription (Homo sapiens)
HES1 gene expression is stimulated by NOTCH3 and STAT1 (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:p-Y701-STAT1 dimer:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex and STAT1 bind HES1 gene promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:p-Y701-STAT1 dimer:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex binds HES1 gene promoter (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
Signaling by NOTCH4 (Homo sapiens)
NOTCH4 Intracellular Domain Regulates Transcription (Homo sapiens)
HES1 gene expression is stimulated by NOTCH4 (Homo sapiens)
HES1 gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000114315 HES1
Gene Names
HES1, BHLHB39, HL, HRY
Participates
as an input of
NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)
NOTCH1 PEST domain mutants bind HES1 promoter (Homo sapiens)
NOTCH2 stimulates HES1 transcription (Homo sapiens)
NOTCH2 coactivator complex binds HES1 promoter (Homo sapiens)
NOTCH3 coactivator complex binds HES1 gene promoter (Homo sapiens)
HES1 gene expression is stimulated by NOTCH3 and STAT1 (Homo sapiens)
NOTCH3 coactivator complex and STAT1 bind HES1 gene promoter (Homo sapiens)
HES1 gene expression is stimulated by NOTCH4 (Homo sapiens)
RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter (Homo sapiens)
HES1 gene transcription is inhibited by RUNX3 (Homo sapiens)
NOTCH1 Coactivator Complex binds HES1 promoter (Homo sapiens)
NOTCH1 stimulates HES1 transcription (Homo sapiens)
as a component of
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:p-Y701-STAT1 dimer:HES1 gene [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
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