NOTCH2 coactivator complex binds HES1 promoter

Stable Identifier
R-HSA-2976716
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NOTCH2 coactivator complex binds HES1 promoter
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NOTCH2 intracellular domain, NICD2, as a part of the NOTCH2 coactivator complex, binds RBPJ elements in the promoter of HES1 gene (Shimizu et al. 2002).

Literature References
PubMed ID Title Journal Year
11866432 Functional diversity among Notch1, Notch2, and Notch3 receptors

Shimizu, K, Hirai, H, Kumano, K, Hamada, Y, Saito, T, Chiba, S

Biochem Biophys Res Commun 2002
Participants
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as an event of
Inferred From
Notch2 binds Hes1 promoter (Mus musculus)
Authored
Orlic-Milacic, M  (2013-01-11)
Reviewed
Ilagan, MXG  (2013-04-25)
Boyle, S  (2013-04-25)
Created
Orlic-Milacic, M  (2013-01-10)
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