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AMBP(20-198) [extracellular region]
Stable Identifier
R-HSA-2168855
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Truncated Alpha1-Microglobulin, Protein AMBP component recommendedName: Alpha-1-microglobulin, AMBP, AMBP_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging of heme from plasma (Homo sapiens)
Alpha-1-Microglobulin is cleaved (Homo sapiens)
AMBP(20-198) [extracellular region] (Homo sapiens)
Truncated Alpha-1-Microglobulin binds heme (Homo sapiens)
AMBP(20-198) [extracellular region] (Homo sapiens)
Truncated Alpha1-Microglobulin:heme trimer [extracellular region] (Homo sapiens)
Truncated Alpha1-Microglobulin:heme [extracellular region] (Homo sapiens)
AMBP(20-198) [extracellular region] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
11877257
Processing of the lipocalin alpha(1)-microglobulin by hemoglobin induces heme-binding and heme-degradation properties
Allhorn, M
,
BerggÄrd, T
,
Nordberg, J
,
Olsson, ML
,
Akerström, B
Blood
2002
External Reference Information
External Reference
UniProt:P02760 AMBP
Gene Names
AMBP, HCP, ITIL
Chain
signal peptide:1-19, chain:20-203, chain:206-352, chain:284-344
Reference Genes
BioGPS Gene:259 AMBP
COSMIC (genes):AMBP AMBP
CTD Gene:259 AMBP
dbSNP Gene:259 AMBP
ENSEMBL:ENSG00000106927 AMBP
ENSEMBL_homo_sapiens_GENE:ENSG00000106927.12 AMBP
HGNC:453 AMBP
KEGG Gene (Homo sapiens):259 AMBP
Monarch:259 AMBP
NCBI Gene:259 AMBP
OMIM:176870 AMBP
UCSC:P02760 AMBP
Reference Transcript
RefSeq:NM_001633.3 AMBP
Other Identifiers
11724511_a_at
11747103_a_at
17097512
205477_PM_s_at
205477_s_at
259
3221801
3221802
3221805
3221807
3221808
3221811
3221812
3221814
3221815
3221816
3221817
3221818
36995_at
8163535
A_23_P256504
GE60517
GO:0002376
GO:0003824
GO:0004867
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005635
GO:0005737
GO:0005739
GO:0005743
GO:0005783
GO:0005829
GO:0005886
GO:0007155
GO:0007565
GO:0009986
GO:0016020
GO:0016491
GO:0019855
GO:0019862
GO:0020037
GO:0022414
GO:0023052
GO:0030246
GO:0030312
GO:0030414
GO:0031012
GO:0031965
GO:0042167
GO:0042803
GO:0043226
GO:0046329
GO:0046904
GO:0050777
GO:0062023
GO:0070062
GO:0072562
GO:0098772
HMNXSV003033683
ILMN_1695446
PH_hs_0004395
TC09001506.hg
g4502066_3p_at
g4502066_3p_x_at
Participates
as a component of
Truncated Alpha1-Microglobulin:heme [extracellular region] (Homo sapiens)
as an input of
Truncated Alpha-1-Microglobulin binds heme (Homo sapiens)
as an output of
Alpha-1-Microglobulin is cleaved (Homo sapiens)
Other forms of this molecule
thioether crosslinked C53-AMBP(20-202) [extracellular region]
AMBP(20-202) [extracellular region]
Inferred To
AMBP [extracellular region]
(Canis familiaris)
AMBP [extracellular region]
(Sus scrofa)
AMBP(20-198) [extracellular region]
(Gallus gallus)
AMBP(20-198) [extracellular region]
(Mus musculus)
AMBP(20-198) [extracellular region]
(Rattus norvegicus)
ambp [extracellular region]
(Danio rerio)
ambp [extracellular region]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001624.1
OpenTargets
ENSG00000106927
GeneCards
P02760
HPA
ENSG00000106927-AMBP
Ensembl
ENST00000265132
,
ENSP00000265132
,
ENSG00000106927
PRO
P02760
Pharos - Targets
P02760
HMDB Protein
HMDBP01676
PDB
6EJC
,
3QKG
,
4ES7
,
4U30
,
6EJB
,
6EJ8
,
6EJ7
,
6EJD
,
1BIK
,
6EJ9
,
6EJA
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P07858 CTSB
6
CTSB(80-333) [lysosomal lumen]
(R-HSA-1181222)
CTSB(129-333) [extracellular region]
(R-HSA-2471625)
CTSB(80-126) [extracellular region]
(R-HSA-2228661)
CTSB(80-333) [extracellular region]
(R-HSA-6801608)
CTSB(80-333) [ficolin-1-rich granule lumen]
(R-HSA-6801299)
CTSB(80-333) [endolysosome lumen]
(R-HSA-1679058)
0.602
4
UniProt:Q13643 FHL3
0.556
3
UniProt:P69616 ORF3
0.527
4
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