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HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane]
Stable Identifier
R-HSA-2130688
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ER to Golgi transport vesicle membrane
Synonyms
HB2P_HUMAN, HLA-DPB1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Formation of COPII vesicle (Homo sapiens)
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Homo sapiens)
Nonameric complex [ER to Golgi transport vesicle membrane] (Homo sapiens)
MHC II alpha/beta dimer [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA II beta chain [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Homo sapiens)
Fusion of COPII vesicle with Golgi complex (Homo sapiens)
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Homo sapiens)
Nonameric complex [ER to Golgi transport vesicle membrane] (Homo sapiens)
MHC II alpha/beta dimer [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA II beta chain [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04440 HLA-DPB1
Gene Names
HLA-DPB1, HLA-DP1B
Chain
signal peptide:1-29, chain:30-258
Reference Genes
BioGPS Gene:3115 HLA-DPB1
COSMIC (genes):HLA-DPB1 HLA-DPB1
CTD Gene:3115 HLA-DPB1
dbSNP Gene:3115 HLA-DPB1
ENSEMBL:ENSG00000215048 HLA-DPB1
ENSEMBL:ENSG00000223865 HLA-DPB1
ENSEMBL:ENSG00000226826 HLA-DPB1
ENSEMBL:ENSG00000230763 HLA-DPB1
ENSEMBL:ENSG00000236693 HLA-DPB1
ENSEMBL:ENSG00000237710 HLA-DPB1
HGNC:4940 HLA-DPB1
KEGG Gene (Homo sapiens):3115 HLA-DPB1
Monarch:3115 HLA-DPB1
NCBI Gene:3115 HLA-DPB1
OMIM:142858 HLA-DPB1
UCSC:P04440 HLA-DPB1
Reference Transcript
RefSeq:NM_002121.5 HLA-DPB1
Other Identifiers
0001940072
11717299_at
11717300_x_at
11755279_x_at
11756073_x_at
11757801_x_at
11758369_x_at
11759666_x_at
17007352
17026444
17031219
17033704
17035971
17038687
17041318
201137_s_at
2903402
2903403
2903413
2903414
2903415
2903422
2903423
2903425
2903428
2903429
2903430
2903431
2903432
2903433
2903434
3115
38095_i_at
38096_f_at
66616_at
8118594
8178220
8179519
A_23_P258769
A_24_P166443
A_33_P3271635
A_33_P3271651
GE61021
GE81120
GE906236
GO:0000139
GO:0002250
GO:0002376
GO:0002504
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006950
GO:0006955
GO:0007155
GO:0007165
GO:0008150
GO:0008283
GO:0009986
GO:0010008
GO:0012507
GO:0016020
GO:0016021
GO:0019882
GO:0019886
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0032588
GO:0032729
GO:0032991
GO:0042102
GO:0042605
GO:0042613
GO:0043226
GO:0050852
GO:0050870
GO:0060333
GO:0071556
ILMN_1749070
M57466_s_at
M83664_at
PH_hs_0024067
Participant Of
hasMember
HLA II beta chain [ER to Golgi transport vesicle membrane]
Other forms of this molecule
HLA class II histocompatibility antigen, DP [transport vesicle membrane]
HLA class II histocompatibility antigen, DP [clathrin-coated endocytic vesicle membrane]
HLA class II histocompatibility antigen, DP [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DP [integral component of lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DP [Golgi membrane]
HLA class II histocompatibility antigen, DP [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DP [lysosomal membrane]
HLA class II histocompatibility antigen, DP [plasma membrane]
Inferred To
si:busm1-228j01.6 [ER to Golgi transport vesicle membrane] (Danio rerio)
mhc2bl [ER to Golgi transport vesicle membrane] (Danio rerio)
BLB3 [ER to Golgi transport vesicle membrane] (Gallus gallus)
mhc2dab [ER to Golgi transport vesicle membrane] (Danio rerio)
mhc2dbb [ER to Golgi transport vesicle membrane] (Danio rerio)
mhc2b [ER to Golgi transport vesicle membrane] (Danio rerio)
BLB1 [ER to Golgi transport vesicle membrane] (Gallus gallus)
LOC101748499 [ER to Golgi transport vesicle membrane] (Gallus gallus)
BLA-DQB [ER to Golgi transport vesicle membrane] (Bos taurus)
si:busm1-228j01.4 [ER to Golgi transport vesicle membrane] (Danio rerio)
SLA-DQB [ER to Golgi transport vesicle membrane] (Sus scrofa)
si:ch73-158p21.3 [ER to Golgi transport vesicle membrane] (Danio rerio)
HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Canis familiaris)
HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Danio rerio)
HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Gallus gallus)
HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
Homologues of HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Danio rerio)
Homologues of HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Gallus gallus)
Homologues of HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane] (Xenopus tropicalis)
si:dkey-33b17.3 [ER to Golgi transport vesicle membrane] (Danio rerio)
si:zfos-2070c2.3 [ER to Golgi transport vesicle membrane] (Danio rerio)
LOC107057103 [ER to Golgi transport vesicle membrane] (Gallus gallus)
Cross References
RefSeq
NP_002112.3
OpenTargets
ENSG00000223865
GeneCards
P04440
HPA
ENSG00000223865-HLA-DPB1
Ensembl
ENSG00000237710
,
ENSG00000223865
,
ENST00000399500
,
ENSG00000215048
,
ENSG00000236693
,
ENSP00000396095
,
ENST00000418931
,
ENST00000454006
,
ENSP00000414196
,
ENSG00000226826
,
ENSG00000230763
,
ENST00000411749
,
ENSP00000382422
,
ENST00000425130
,
ENST00000433800
,
ENSP00000389288
,
ENSP00000407674
,
ENSP00000408146
PRO
P04440
Orphanet
22272
PDB
4P57
,
4P4K
,
3LQZ
,
4P4R
,
4P5M
,
4P5K
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96CV9 OPTN
4
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
0.556
3
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