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IL18R1 [plasma membrane]
Stable Identifier
R-HSA-197600
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Interleukin-18 receptor 1 precursor, IR18_HUMAN, IL1RRP
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-18 signaling (Homo sapiens)
IL18 binds IL18R1 (Homo sapiens)
IL18:IL18R1 [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
IL18:IL18R1 binds IL18RAP (Homo sapiens)
IL18:IL18R1 [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
IL18:IL18R1:IL18RAP [plasma membrane] (Homo sapiens)
IL18:IL18R1 [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
Interleukin-37 signaling (Homo sapiens)
IL37 binds IL18R1 (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
IL18R1:IL37,IL37(?-218) [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
IL37:IL18R1 binds SIGIRR (Homo sapiens)
IL18R1:IL37,IL37(?-218) [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane] (Homo sapiens)
IL18R1:IL37,IL37(?-218) [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
STAT3 phosphorylation (Homo sapiens)
IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane] (Homo sapiens)
IL18R1:IL37,IL37(?-218) [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
TBK1 phosphorylation (Homo sapiens)
IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane] (Homo sapiens)
IL18R1:IL37,IL37(?-218) [plasma membrane] (Homo sapiens)
IL18R1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13478 IL18R1
Gene Names
IL18R1, IL1RRP
Chain
signal peptide:1-18, chain:19-541
Reference Genes
BioGPS Gene:8809 IL18R1
COSMIC (genes):IL18R1 IL18R1
CTD Gene:8809 IL18R1
dbSNP Gene:8809 IL18R1
ENSEMBL:ENSG00000115604 IL18R1
HGNC:5988 IL18R1
KEGG:hsa:8809 IL18R1
Monarch:8809 IL18R1
NCBI Gene:8809 IL18R1
OMIM:604494 IL18R1
UCSC:Q13478 IL18R1
Reference Transcript
RefSeq:NM_003855.3 IL18R1
RefSeq:NM_001282399.1 IL18R1
Other Identifiers
11735275_at
11735276_a_at
16883715
206618_PM_at
206618_at
2497083
2497112
2497114
2497116
2497118
2497120
2497121
2497122
2497124
2497125
2497126
2497128
2497131
2497132
2497134
2497135
2497136
2497137
2497139
2497144
2497145
2497147
2497148
2497149
2497150
2497151
2497152
2497153
2497154
36377_at
8044035
85412_r_at
8809
A_14_P113967
A_23_P39735
A_24_P208567
A_33_P3211666
A_33_P3251876
GE62434
GE700545
GO:0002376
GO:0003824
GO:0003953
GO:0004908
GO:0005515
GO:0005886
GO:0006355
GO:0006954
GO:0006955
GO:0007165
GO:0016020
GO:0016787
GO:0030101
GO:0030154
GO:0032729
GO:0035655
GO:0038023
GO:0042007
GO:0042008
GO:0045063
GO:0045092
GO:0051092
GO:0060089
GO:0061809
GO:0120163
GO:1901224
GO:2000556
HMNXSV003025163
ILMN_1781700
PH_hs_0009687
TC02004995.hg
U43672_at
g4504654_3p_at
Participates
as a component of
IL18:IL18R1 [plasma membrane] (Homo sapiens)
IL18R1:IL37,IL37(?-218) [plasma membrane] (Homo sapiens)
as an input of
IL18 binds IL18R1 (Homo sapiens)
IL37 binds IL18R1 (Homo sapiens)
Inferred To
LOC100491382 [plasma membrane]
(Xenopus tropicalis)
IL1RL1 [plasma membrane]
(Canis familiaris)
Il18r1 [plasma membrane]
(Mus musculus)
Il18r1 [plasma membrane]
(Rattus norvegicus)
IL18R1 [plasma membrane]
(Bos taurus)
IL18R1 [plasma membrane]
(Gallus gallus)
IL18R1 [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
1737
ENSEMBL
ENSG00000115604
,
ENST00000410040
,
ENSP00000387211
,
ENSP00000386663
,
ENST00000233957
,
ENST00000409599
,
ENSP00000233957
OpenTargets
ENSG00000115604
GeneCards
IL18R1
HPA
ENSG00000115604-IL18R1
PRO
Q13478
Pharos - Targets
Q13478
GlyGen
Q13478
HMDB Protein
HMDBP12400
PDB
3WO4
,
3WO3
,
4R6U
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14116 IL18
4
IL18(1-193) [cytosol]
(R-HSA-449033)
IL18 [cytosol]
(R-HSA-449023)
IL18(1-36) [cytosol]
(R-HSA-449062)
IL18 [extracellular region]
(R-HSA-448446)
0.558
2
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