IL18 binds IL18R1

Stable Identifier
R-HSA-8848370
Type
Reaction
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
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IL18 binds IL18R1
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Interleukin-18 (IL18) binds IL18 receptor alpha chain (IL18R1), with low affinity (Torigoe et al. 1997, Kato et al. 2007).

Literature References
PubMed ID Title Journal Year
9325300 Purification and characterization of the human interleukin-18 receptor

Ushio, S, Ikegami, H, Kunikata, T, Ikeda, M, Kurimoto, M, Kojima, H, Murakami, T, Ohta, T, Okura, T, Kobayashi, S, Fujii, M, Torigoe, K, Taniai, M, Sanou, O

J. Biol. Chem. 1997
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
IL18BP:IL18 [extracellular region] (Homo sapiens)
Positively by
Regulator
IL18-2(37-189) [extracellular region] (Homo sapiens)
Authored
Jupe, S  (2014-06-04)
Reviewed
Meldal, BH  (2016-01-28)
Created
Jupe, S  (2015-12-08)
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