Interaction of Bnip-2 with Cdc42

Stable Identifier
R-HSA-376119
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Bnip-2 interacts with Cdc42 through its Bnip-2 and Cdc42GAP homology (BCH) domain and thus it acts as a linkage between the CDO receptor and the Cdc42 activity. Formation of a CDO-Bnip-2-Cdc42 complex stimulates Cdc42 activation which in turn promotes p38 alpha/beta activity and cell differentiation.

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