Interaction of Bnip-2 with Cdc42

Stable Identifier
R-HSA-376119
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
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Interaction of Bnip-2 with Cdc42
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Bnip-2 interacts with Cdc42 through its Bnip-2 and Cdc42GAP homology (BCH) domain and thus it acts as a linkage between the CDO receptor and the Cdc42 activity. Formation of a CDO-Bnip-2-Cdc42 complex stimulates Cdc42 activation which in turn promotes p38 alpha/beta activity and cell differentiation.

Participants
Input
Output
Participant Of
hasEvent
Inferred From
Interaction of Bnip-2 with Cdc42 (Mus musculus)
Authored
Garapati, P V  (2008-08-11)
Reviewed
Krauss, RS  (2010-02-09)
Created
Garapati, P V  (2008-09-05)