Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p-T180,Y182-MAPK13 [cytosol]
Stable Identifier
R-HSA-171022
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Phospho-MAP kinase p38 delta, P-MAPK13
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Homo sapiens)
NOD1/2 Signaling Pathway (Homo sapiens)
Activation of p38 MAPK (Homo sapiens)
Phospho-p38 MAPK [cytosol] (Homo sapiens)
p-T180,Y182-MAPK13 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15264 MAPK13
Gene Names
MAPK13, PRKM13, SAPK4
Chain
chain:1-365
Reference Genes
BioGPS Gene:5603 MAPK13
COSMIC (genes):MAPK13 MAPK13
CTD Gene:5603 MAPK13
dbSNP Gene:5603 MAPK13
ENSEMBL:ENSG00000156711 MAPK13
HGNC:6875 MAPK13
KEGG:hsa:5603 MAPK13
Monarch:5603 MAPK13
NCBI Gene:5603 MAPK13
OMIM:602899 MAPK13
UCSC:O15264 MAPK13
Reference Transcript
RefSeq:NM_002754.4 MAPK13
Other Identifiers
11721540_a_at
11748676_a_at
11758147_s_at
17007910
210058_PM_at
210058_at
210059_PM_s_at
210059_s_at
2904947
2904948
2904949
2904950
2904951
2904952
2904953
2904954
2904955
2904956
2904957
2904958
2904959
2904960
2904961
2904962
2904963
2904964
2904965
2904966
2904967
2904968
2904969
2904970
2904971
2904972
2904973
2904974
2904975
2904976
2904977
33245_at
43949_at
5603
8119016
A_23_P145376
A_24_P406132
A_32_P19262
GE54058
GO:0000165
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006468
GO:0006970
GO:0016301
GO:0016740
GO:0018105
GO:0032755
GO:0034644
GO:0035556
GO:0043226
GO:0050729
GO:0051403
GO:0070301
GO:0071347
GO:0072709
GO:0072740
GO:0106310
GO:0140096
GO:1903936
HMNXSV003032717
ILMN_1749327
PH_hs_0010614
TC06000524.hg
g12653328_3p_at
g12653328_3p_s_at
Participates
as a candidate of
Phospho-p38 MAPK [cytosol] (Homo sapiens)
Other forms of this molecule
MAPK13 [cytosol]
Inferred To
phospho-MAPK13 [cytosol]
(Bos taurus)
phospho-MAPK13 [cytosol]
(Canis familiaris)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Caenorhabditis elegans)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Dictyostelium discoideum)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Drosophila melanogaster)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Mus musculus)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Rattus norvegicus)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Saccharomyces cerevisiae)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Schizosaccharomyces pombe)
phospho-p-T180,Y182-MAPK13 [cytosol]
(Sus scrofa)
phospho-gskl-2 [cytosol]
(Caenorhabditis elegans)
Homologues of p-T180,Y182-MAPK13 [cytosol]
(Caenorhabditis elegans)
Homologues of p-T180,Y182-MAPK13 [cytosol]
(Dictyostelium discoideum)
Homologues of p-T180,Y182-MAPK13 [cytosol]
(Drosophila melanogaster)
Modified Residues
Name
O-phospho-L-threonine at 180
Coordinate
180
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O4'-phospho-L-tyrosine at 182
Coordinate
182
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_002745.1
ZINC - World Drugs
MK13_HUMAN
Guide to Pharmacology - Targets
1502
ENSEMBL
ENST00000373766
,
ENSP00000211287
,
ENSP00000362871
,
ENST00000211287
OpenTargets
ENSG00000156711
ZINC - FDA approved
MK13_HUMAN
ZINC - Substances
MK13_HUMAN
ZINC - Biogenic
MK13_HUMAN
ZINC target
O15264
PRO
O15264
PDB
4EYM
,
5EKO
,
4EYJ
,
8X23
,
5EKN
,
4MYG
,
3COI
,
4YNO
ZINC - Investigational
MK13_HUMAN
HPA
ENSG00000156711-MAPK13
Pharos - Targets
O15264
ZINC - Predictions - Purchasable
MK13_HUMAN
HMDB Protein
HMDBP01327
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53778 MAPK12
3
MAPK12 [cytosol]
(R-HSA-171025)
p-T183,Y185-MAPK12 [cytosol]
(R-HSA-171021)
MAPK12 [nucleoplasm]
(R-HSA-448833)
0.643
4
UniProt:P21462 FPR1
4
FPR1 [azurophil granule membrane]
(R-HSA-6799143)
FPR1 [secretory granule membrane]
(R-HSA-6800929)
FPR1 [ficolin-1-rich granule membrane]
(R-HSA-6800878)
FPR1 [plasma membrane]
(R-HSA-375450)
0.499
3
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text