Reactome | CYC1 [mitochondrial inner membrane]

CYC1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-164277

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

cytochrome c1 respiratory subunit of complex III

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P08574 CYC1

Gene Names

CYC1

Chain

transit peptide:1-84, chain:85-325

Reference Genes

BioGPS Gene:1537 CYC1

COSMIC (genes):CYC1 CYC1

CTD Gene:1537 CYC1

dbSNP Gene:1537 CYC1

ENSEMBL:ENSG00000179091 CYC1

HGNC:2579 CYC1

KEGG:hsa:1537 CYC1

Monarch:1537 CYC1

NCBI Gene:1537 CYC1

OMIM:123980 CYC1

UCSC:P08574 CYC1

Reference Transcript

RefSeq:NM_001916.4 CYC1

Other Identifiers

1160_at

11754027_x_at

11757429_a_at

11757524_x_at

1537

17073565

201066_PM_at

201066_at

3120052

3120053

3120054

3120055

3120056

3120057

3120058

3120059

3120060

3120061

3120062

3120063

35819_at

8148728

A_14_P127822

A_23_P20980

GE59686

GO:0003824

GO:0005215

GO:0005515

GO:0005634

GO:0005739

GO:0005743

GO:0006091

GO:0006122

GO:0008121

GO:0009055

GO:0016020

GO:0016491

GO:0020037

GO:0033762

GO:0043226

GO:0045275

GO:0045333

GO:0046872

GO:0055085

GO:1902600

HMNXSV003031399

ILMN_1815115

J04444_at

PH_hs_0015038

TC08000840.hg

g4503184_3p_s_at

Participates

as a component of

CYC1:heme c [mitochondrial inner membrane] (Homo sapiens)

Other forms of this molecule

CYC1(1-325) [mitochondrial intermembrane space]

CYC1(1-325) [cytosol]

Inferred To

Ghost homologue of CYC1 [mitochondrial inner membrane] (Gallus gallus)

CYC1 [mitochondrial inner membrane] (Bos taurus)

CYC1 [mitochondrial inner membrane] (Caenorhabditis elegans)

CYC1 [mitochondrial inner membrane] (Danio rerio)

CYC1 [mitochondrial inner membrane] (Dictyostelium discoideum)

CYC1 [mitochondrial inner membrane] (Drosophila melanogaster)

CYC1 [mitochondrial inner membrane] (Mus musculus)

CYC1 [mitochondrial inner membrane] (Rattus norvegicus)

CYC1 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

CYC1 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

CYC1 [mitochondrial inner membrane] (Sus scrofa)

Cross References

ENSEMBL

ENSP00000317159, ENST00000318911

OpenTargets

ENSG00000179091

HPA

ENSG00000179091-CYC1

PRO

P08574

Pharos - Targets

P08574

GlyGen

P08574

Orphanet

CYC1

HMDB Protein

HMDBP00991

PDB

5XTE, 5XTH, 5XTI

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	7
UniProt:P14927 UQCRB	1	UQCRB [mitochondrial inner membrane] (R-HSA-164287)	0.641	3
UniProt:P40855 PEX19	1	PEX19 [cytosol] (R-HSA-3009036)	0.527	4
UniProt:P07919 UQCRH	1	UQCRH [mitochondrial inner membrane] (R-HSA-164286)	0.527	2
UniProt:P53701 HCCS	1	HCCS [mitochondrial inner membrane] (R-HSA-9866218)	0.527	2