Reactome | NDUFV1 [mitochondrial inner membrane]

NDUFV1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-163926

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase 51 kDa subunit

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P49821 NDUFV1

Gene Names

NDUFV1, UQOR1

Chain

transit peptide:1-20, chain:21-464

Reference Genes

BioGPS Gene:4723 NDUFV1

COSMIC (genes):NDUFV1 NDUFV1

CTD Gene:4723 NDUFV1

dbSNP Gene:4723 NDUFV1

ENSEMBL:ENSG00000167792 NDUFV1

ENSEMBL:ENSG00000167792.13 NDUFV1

HGNC:7716 NDUFV1

KEGG Gene (Homo sapiens):4723 NDUFV1

Monarch:4723 NDUFV1

NCBI Gene:4723 NDUFV1

OMIM:161015 NDUFV1

UCSC:P49821 NDUFV1

Reference Transcript

Other Identifiers

11717759_a_at

16727933

16727936

208714_PM_at

208714_at

3337197

3337198

3337202

3337204

3337206

3337209

3337211

3337212

3337216

3337217

3337219

3337222

3337223

3337224

37329_at

4723

7941946

A_14_P132982

A_23_P127353

A_33_P3317406

GE81726

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005747

GO:0005829

GO:0006091

GO:0006120

GO:0008137

GO:0009060

GO:0010181

GO:0016020

GO:0016491

GO:0022900

GO:0042775

GO:0042776

GO:0043226

GO:0045271

GO:0046872

GO:0051287

GO:0051536

GO:0051539

GO:0055086

GO:0070469

GO:1901135

HMNXSV003015140

HMNXSV003021642

ILMN_1786718

ILMN_1870931

PH_hs_0000797

TC11000695.hg

TC11000696.hg

g5138911_3p_at

p2806

Participates

as an input of

NUBPL transfers 4Fe-4S to NDUFV1, V2 (Homo sapiens)

as a component of

NDUFV1:4Fe-4S:FMN [mitochondrial inner membrane] (Homo sapiens)

Inferred To

nuo-1 [mitochondrial inner membrane] (Caenorhabditis elegans)

ND-51 [mitochondrial inner membrane] (Drosophila melanogaster)

Ghost homologue of NDUFV1 [mitochondrial inner membrane] (Gallus gallus)

wu:fc01f01 [mitochondrial inner membrane] (Danio rerio)

NDUFV1 [mitochondrial inner membrane] (Bos taurus)

NDUFV1 [mitochondrial inner membrane] (Canis familiaris)

NDUFV1 [mitochondrial inner membrane] (Dictyostelium discoideum)

NDUFV1 [mitochondrial inner membrane] (Mus musculus)

NDUFV1 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

NDUFV1 [mitochondrial inner membrane] (Sus scrofa)

Ndufv1 [mitochondrial inner membrane] (Rattus norvegicus)

me1 [mitochondrial inner membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001159574.1, NP_009034.2

OpenTargets

ENSG00000167792

GeneCards

P49821

HPA

ENSG00000167792-NDUFV1

Ensembl

ENSG00000167792, ENSP00000436766, ENST00000322776, ENSP00000322450, ENSP00000497587, ENST00000647561, ENST00000529927

PRO

P49821

Pharos - Targets

P49821

Orphanet

16533

HMDB Protein

HMDBP00186

PDB

5XTH, 5XTI, 5XTD, 5XTB

Interactors (28)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P56181 NDUFV3	1	NDUFV3 [mitochondrial inner membrane] (R-HSA-163943)	0.564	2
UniProt:O43678 NDUFA2	1	NDUFA2 [mitochondrial inner membrane] (R-HSA-60178)	0.564	3
UniProt:Q6P3S6 FBX42			0.556	3
UniProt:Q9H871 RMD5A			0.556	3
UniProt:Q99932-2 SPAG8			0.556	3
UniProt:Q9NTX7-2 RNF146			0.556	3
UniProt:Q96CV9-2 OPTN			0.556	3
UniProt:Q7Z6E9-3 RBBP6			0.556	3
UniProt:Q9NP61 ARFGAP3	1	ARFGAP3 [cytosol] (R-HSA-6807740)	0.556	3
UniProt:P45880 VDAC2	2	PolyUb-VDAC2 [mitochondrial outer membrane] (R-HSA-6783185) VDAC2 [mitochondrial outer membrane] (R-HSA-5696880)	0.556	3
UniProt:Q96B65 Q96B65			0.556	3
UniProt:Q8TAP4-4 LMO3			0.556	3
UniProt:Q16401 PSMD5	2	PSMD5 [nucleoplasm] (R-HSA-174346) PSMD5 [cytosol] (R-HSA-68802)	0.556	3
UniProt:P20618 PSMB1	5	PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [nucleoplasm] (R-HSA-174347) PSMB1 [cytosol] (R-HSA-68738)	0.556	3
UniProt:P41218 MNDA	3	MNDA [azurophil granule lumen] (R-HSA-6799237) MNDA [extracellular region] (R-HSA-6806244) MNDA [ficolin-1-rich granule lumen] (R-HSA-6800897)	0.556	3
UniProt:P61201 COPS2	2	COPS2 [cytosol] (R-HSA-416971) COPS2 [nucleoplasm] (R-HSA-5697012)	0.556	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.556	3
UniProt:Q8WUA7-2 Q8WUA72			0.556	3
UniProt:Q9Y297 BTRC	2	BTRC [cytosol] (R-HSA-174237) BTRC [nucleoplasm] (R-HSA-3361753)	0.556	3
UniProt:Q2TAY7 SMU1	1	SMU1 [nucleoplasm] (R-HSA-9770259)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:P17252 PRKCA	8	PRKCA [cytosol] (R-HSA-58196) pT497,T638,S657-PRKCA [plasma membrane] (R-HSA-4332340) p-T497,T638,S657-PRKCA [cytosol] (R-HSA-4332337) PRKCA [plasma membrane] (R-HSA-156469) p-T497-PRKCA [cytosol] (R-HSA-5218731) p-T497,T638,S657-PRKCA [nucleoplasm] (R-HSA-5223292) PRKCA [photoreceptor disc membrane] (R-HSA-2648987) PRKCA [nucleoplasm] (R-HSA-450530)	0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:P25788-2 PSMA3			0.556	3
UniProt:Q8TCJ0-3 FBXO25			0.556	3
UniProt:Q8IZU1 FAM9A			0.556	3
UniProt:Q15047-2 SETDB1			0.556	3
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.527	6

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