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NDUFV3 [mitochondrial inner membrane]
Stable Identifier
R-HSA-163943
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
NADH-ubiquinone oxidoreductase 9 kDa subunit
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex I biogenesis (Homo sapiens)
NDUF subunits bind to form the FP subcomplex (Homo sapiens)
FP subcomplex [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Homo sapiens)
980kDa complex [mitochondrial inner membrane] (Homo sapiens)
FP subcomplex [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
FP subcomplex [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Homo sapiens)
980kDa complex [mitochondrial inner membrane] (Homo sapiens)
FP subcomplex [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
Complex I [mitochondrial inner membrane] (Homo sapiens)
FP subcomplex (-NDUFAF2) [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Homo sapiens)
Complex I [mitochondrial inner membrane] (Homo sapiens)
FP subcomplex (-NDUFAF2) [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Mitochondrial protein degradation (Homo sapiens)
LONP1 binds mitochondrial inner membrane proteins (Homo sapiens)
LONP1:substrate protein (mitochondrial inner membrane) [mitochondrial matrix] (Homo sapiens)
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
LONP1 degrades mitochondrial inner membrane proteins (Homo sapiens)
LONP1:substrate protein (mitochondrial inner membrane) [mitochondrial matrix] (Homo sapiens)
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
NDUFV3 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P56181 NDUFV3
Gene Names
NDUFV3
Chain
transit peptide:1-34, chain:35-108
Reference Genes
BioGPS Gene:4731 NDUFV3
COSMIC (genes):NDUFV3 NDUFV3
CTD Gene:4731 NDUFV3
dbSNP Gene:4731 NDUFV3
ENSEMBL:ENSG00000160194 NDUFV3
HGNC:7719 NDUFV3
KEGG:hsa:4731 NDUFV3
Monarch:4731 NDUFV3
NCBI Gene:4731 NDUFV3
OMIM:602184 NDUFV3
UCSC:P56181 NDUFV3
Reference Transcript
RefSeq:NM_021075.3 NDUFV3
RefSeq:NM_001001503.1 NDUFV3
Other Identifiers
11723072_x_at
11723449_a_at
11745460_at
16923271
226209_PM_at
226209_at
226616_PM_s_at
226616_s_at
2406606
3922922
3922923
3922926
3922929
3922930
3922931
3922935
3922937
3922938
3922944
3922945
3922946
3922947
3922948
3922957
3922959
4731
52154_at
8068857
91619_s_at
91622_at
A_23_P211285
A_24_P241995
A_24_P416951
A_32_P1360
GE60222
GO:0003723
GO:0003824
GO:0005215
GO:0005515
GO:0005739
GO:0005743
GO:0005747
GO:0006091
GO:0006120
GO:0008137
GO:0009060
GO:0016491
GO:0042775
GO:0042776
GO:0043226
GO:0045271
GO:0055085
GO:0055086
GO:1901135
GO:1902600
HMNXSV003010360
HMNXSV003025528
Hs.59745.1.S1_3p_a_at
ILMN_1765500
ILMN_2387731
PH_hs_0022967
PH_hs_0032130
TC21000751.hg
TC21001063.hg
X99728_at
p21706
Participates
as a member of
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
as an input of
NDUF subunits bind to form the FP subcomplex (Homo sapiens)
as a component of
FP subcomplex [mitochondrial inner membrane] (Homo sapiens)
FP subcomplex (-NDUFAF2) [mitochondrial inner membrane] (Homo sapiens)
Inferred To
Ghost homologue of NDUFV3 [mitochondrial inner membrane]
(Caenorhabditis elegans)
Ghost homologue of NDUFV3 [mitochondrial inner membrane]
(Canis familiaris)
Ghost homologue of NDUFV3 [mitochondrial inner membrane]
(Danio rerio)
Ghost homologue of NDUFV3 [mitochondrial inner membrane]
(Drosophila melanogaster)
Ghost homologue of NDUFV3 [mitochondrial inner membrane]
(Sus scrofa)
Ndufv3 [mitochondrial inner membrane]
(Mus musculus)
Ndufv3 [mitochondrial inner membrane]
(Rattus norvegicus)
NDUFV3 [mitochondrial inner membrane]
(Bos taurus)
NDUFV3 [mitochondrial inner membrane]
(Gallus gallus)
Homologues of NDUFV3 [mitochondrial inner membrane]
(Bos taurus)
ndufv3 [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000354250
,
ENSP00000342895
,
ENSP00000346196
,
ENST00000340344
OpenTargets
ENSG00000160194
HPA
ENSG00000160194-NDUFV3
PRO
P56181
Pharos - Targets
P56181
HMDB Protein
HMDBP00148
PDB
5XTB
,
5XTD
,
5XTH
,
5XTI
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49821 NDUFV1
1
NDUFV1 [mitochondrial inner membrane]
(R-HSA-163926)
0.669
5
UniProt:O75489 NDUFS3
2
NDUFS3 [mitochondrial matrix]
(R-HSA-163927)
NDUFS3 [cytosol]
(R-HSA-9714751)
0.643
6
UniProt:O43678 NDUFA2
1
NDUFA2 [mitochondrial inner membrane]
(R-HSA-60178)
0.564
5
UniProt:Q9UI09 NDUFA12
1
NDUFA12 [mitochondrial inner membrane]
(R-HSA-59864)
0.527
4
UniProt:O75380 NDUFS6
1
NDUFS6 [mitochondrial inner membrane]
(R-HSA-163922)
0.527
4
UniProt:P56556 NDUFA6
1
NDUFA6 [mitochondrial inner membrane]
(R-HSA-59932)
0.527
4
UniProt:Q16795 NDUFA9
1
NDUFA9 [mitochondrial matrix]
(R-HSA-163942)
0.527
4
UniProt:O43920 NDUFS5
1
NDUFS5 [mitochondrial inner membrane]
(R-HSA-60226)
0.527
4
UniProt:O43181 NDUFS4
1
NDUFS4 [mitochondrial inner membrane]
(R-HSA-163946)
0.527
4
UniProt:P19404 NDUFV2
1
NDUFV2 [mitochondrial inner membrane]
(R-HSA-163939)
0.527
4
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