Reactome | CERK [plasma membrane]

CERK [plasma membrane]

Stable Identifier

R-HSA-1631584

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Ceramide kinase, CERK1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8TCT0 CERK

Gene Names

CERK, KIAA1646

Chain

chain:1-537

Reference Genes

BioGPS Gene:64781 CERK

COSMIC (genes):CERK CERK

CTD Gene:64781 CERK

dbSNP Gene:64781 CERK

ENSEMBL:ENSG00000100422 CERK

ENSEMBL:ENSG00000100422.14 CERK

HGNC:19256 CERK

KEGG Gene (Homo sapiens):64781 CERK

Monarch:64781 CERK

NCBI Gene:64781 CERK

OMIM:610307 CERK

UCSC:Q8TCT0 CERK

Reference Transcript

RefSeq:NM_022766.5 CERK

Other Identifiers

11717115_at

11717116_at

11750997_a_at

16936137

218421_PM_at

218421_at

3964156

3964157

3964158

3964159

3964160

3964161

3964162

3964163

3964164

3964165

3964166

3964168

3964170

3964171

3964172

3964173

3964174

3964178

3964179

3964186

3964187

3964188

51239_at

59011_at

64781

8076792

A_23_P211659

A_24_P62237

GE56762

GE85505

GO:0000166

GO:0000287

GO:0001729

GO:0003824

GO:0005515

GO:0005524

GO:0005737

GO:0005886

GO:0006629

GO:0006672

GO:0006687

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0046834

GO:0102773

GO:1901135

HMNXSV003018316

ILMN_1721325

ILMN_1767475

ILMN_2388975

PH_hs_0002840

TC22000890.hg

TC22001398.hg

g12232440_3p_at

Inferred To

Cerk [plasma membrane] (Drosophila melanogaster)

Cerk [plasma membrane] (Rattus norvegicus)

cerk [plasma membrane] (Xenopus tropicalis)

CERK [plasma membrane] (Bos taurus)

CERK [plasma membrane] (Caenorhabditis elegans)

CERK [plasma membrane] (Canis familiaris)

CERK [plasma membrane] (Gallus gallus)

CERK [plasma membrane] (Mus musculus)

CERK [plasma membrane] (Sus scrofa)

si:ch211-162i19.1 [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_073603.2

Guide to Pharmacology - Targets

2473

OpenTargets

ENSG00000100422

GeneCards

Q8TCT0

HPA

ENSG00000100422-CERK

Ensembl

ENSP00000216264, ENST00000216264, ENSG00000100422

ZINC target

Q8TCT0

PRO

Q8TCT0

Pharos - Targets

Q8TCT0

HMDB Protein

HMDBP01405

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q3LI66 KRTAP6-2	1	KRTAP6-2 [cytosol] (R-HSA-6810261)	0.556	3
UniProt:Q8IUC1 KRTAP11-1	1	KRTAP11-1 [cytosol] (R-HSA-6810294)	0.556	3
UniProt:O76011 KRT34	1	KRT34 [cytosol] (R-HSA-6809608)	0.556	3
IntAct:EBI-10171679 386682			0.556	3
UniProt:P0DPK4 NT2NC			0.556	3
UniProt:Q07627 KRTAP1-1	1	KRTAP1-1 [cytosol] (R-HSA-6809855)	0.556	3
UniProt:Q7Z3S9 NT2NA			0.556	3
UniProt:Q8IUB9 KRTAP19-1	1	KRTAP19-1 [cytosol] (R-HSA-6810285)	0.556	3
UniProt:Q9H8W4 PKHF2			0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:P05813 CRBA1			0.556	3
UniProt:Q8IWZ5 TRI42			0.556	3
UniProt:Q9BYR7 KRTAP3-2	1	KRTAP3-2 [cytosol] (R-HSA-6809857)	0.556	3
UniProt:Q9BYQ4 KRTAP9-2	1	KRTAP9-2 [cytosol] (R-HSA-6809965)	0.556	3
UniProt:O43482 OIP5	1	OIP5 [nucleoplasm] (R-HSA-606286)	0.556	3
UniProt:P0CG21 NHLC4			0.556	3
UniProt:Q3LI70 KRTAP19-6	1	KRTAP19-6 [cytosol] (R-HSA-6810286)	0.556	3
UniProt:Q9BYR8 KRTAP3-1	1	KRTAP3-1 [cytosol] (R-HSA-6809868)	0.556	3
UniProt:P13196 ALAS1	2	PXLP-ALAS1 [mitochondrial matrix] (R-HSA-1022086) ALAS1 [mitochondrial matrix] (R-HSA-189438)	0.556	3
UniProt:A8MQ03 CRTP1			0.556	3

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