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KNG1(19-380) [plasma membrane]
Stable Identifier
R-HSA-158245
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
kininogen heavy chain, high molecular weight kininogen heavy chain
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)
Intrinsic Pathway of Fibrin Clot Formation (Homo sapiens)
kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Homo sapiens)
activated kininogen:C1q binding protein tetramer [plasma membrane] (Homo sapiens)
activated kininogen [plasma membrane] (Homo sapiens)
KNG1(19-380) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01042 KNG1
Gene Names
KNG1, BDK, KNG
Chain
signal peptide:1-18, chain:19-644, chain:19-380, peptide:376-389, peptide:380-389, peptide:381-389, chain:390-644, peptide:431-434
Reference Genes
COSMIC (genes):KNG1 KNG1
dbSNP Gene:3827 KNG1
ENSEMBL:ENSG00000113889 KNG1
Participates
as a component of
activated kininogen [plasma membrane] (Homo sapiens)
Other forms of this molecule
KNG1(19-644) [platelet alpha granule lumen]
KNG1(390-644) [plasma membrane]
KNG1(19-644) [plasma membrane]
KNG1(19-644) [extracellular region]
p-KNG1 [endoplasmic reticulum lumen]
KNG1 [endoplasmic reticulum lumen]
Bradykinin [extracellular region]
Inferred To
KNG1 [plasma membrane]
(Bos taurus)
KNG1 [plasma membrane]
(Canis familiaris)
KNG1 [plasma membrane]
(Sus scrofa)
kng1 [plasma membrane]
(Xenopus tropicalis)
Kng1 [plasma membrane]
(Rattus norvegicus)
KNG1(19-380) [plasma membrane]
(Gallus gallus)
Kng2 [plasma membrane]
(Mus musculus)
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q10714
2
ACE(30-1232) [extracellular region]
(R-DME-2065414-2)
ACE(30-1306) [plasma membrane]
(R-DME-508496-2)
0.558
2
UniProt:Q07021 C1QBP
3
C1QBP [plasma membrane]
(R-HSA-158123)
C1QBP [mitochondrial matrix]
(R-HSA-9645697)
C1QBP [cytosol]
(R-HSA-9645690)
0.544
4
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