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ANAPC1 [cytosol]
Stable Identifier
R-HSA-174189
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Apc1/Tsg24
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
Mitotic Spindle Checkpoint (Homo sapiens)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
Binding of the MCC complex to the APC/C complex (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Separation of Sister Chromatids (Homo sapiens)
Association of Securin with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated cell cycle proteins (Homo sapiens)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of Cyclin B (Homo sapiens)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Cyclin B (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
APC/C:Cdc20 mediated degradation of Securin (Homo sapiens)
Association of Securin with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Homo sapiens)
APC-Cdc20 mediated degradation of Nek2A (Homo sapiens)
Association of Nek2A with MCC:APC/C (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Nek2A (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Multiubiquitination of Nek2A (Homo sapiens)
Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Homo sapiens)
Association of Cyclin A with the APC/C (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Degradation multiubiquitinated Cyclin A (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)
Association of Cdh1 with the APC/C (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Dissociation of Cdc20 from APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Regulation of APC/C activators between G1/S and early anaphase (Homo sapiens)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
Binding of the MCC complex to the APC/C complex (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H1A4 ANAPC1
Gene Names
ANAPC1, TSG24
Chain
chain:1-1944
Reference Genes
BioGPS Gene:64682 ANAPC1
COSMIC (genes):ANAPC1 ANAPC1
CTD Gene:64682 ANAPC1
dbSNP Gene:64682 ANAPC1
ENSEMBL:ENSG00000153107 ANAPC1
HGNC:19988 ANAPC1
KEGG:hsa:64682 ANAPC1
Monarch:64682 ANAPC1
NCBI Gene:64682 ANAPC1
OMIM:608473 ANAPC1
UCSC:Q9H1A4 ANAPC1
Reference Transcript
RefSeq:NM_022662.3 ANAPC1
Other Identifiers
11721892_a_at
16901830
17122274
218575_PM_at
218575_at
229267_PM_at
229267_at
231973_PM_s_at
231973_s_at
2492217
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2492240
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2492649
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2498794
2563002
2563078
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2563091
2563092
2563094
2563096
2563114
2563115
2563116
2563488
2563490
2563491
2563493
2569131
2569132
2569134
2569136
2569138
2569140
2571077
2571078
2571079
2571080
2571081
2571082
2571083
2571084
2571085
2571086
2571087
2571089
2571090
2571091
2571092
2571093
2571094
2571095
2571096
2571097
2571098
2571099
2571101
2571102
2571103
2571104
2571106
2571107
2571108
2571109
2571110
2571111
2571116
2571117
2571119
2571120
2571121
2571123
2571125
2571126
2571127
2571130
2571131
2571132
2571133
2571134
2571135
2571136
2571137
2571138
2571140
2571141
2571142
2571143
2571144
2571145
2571146
2571147
2571148
2571149
2571150
2571151
2571153
2571154
2571155
2571156
2571157
2571158
2571159
2571160
2571161
2571162
2571163
2571164
2571165
2571166
52704_at
58914_at
62100_at
62102_at
64682
68608_at
78458_at
8043322
8043349
8053610
8054437
8054614
A_23_P17204
A_33_P3262138
A_33_P3363655
GE55720
GO:0005634
GO:0005654
GO:0005680
GO:0005829
GO:0007091
GO:0007346
GO:0016567
GO:0030163
GO:0031145
GO:0043226
GO:0051301
GO:0051445
GO:0060090
GO:0070936
GO:0070979
GO:0141198
HMNXSV003005463
HMNXSV003007949
HMNXSV003008717
HMNXSV003026519
HMNXSV003031735
HMNXSV003037673
HMNXSV003045399
HMNXSV003053430
HMNXSV003054837
HMNXSV003055651
Hs.30864.0.A1_3p_at
Hs.40137.2.A1_3p_a_at
ILMN_1659553
ILMN_1664435
ILMN_1719149
ILMN_1804812
PH_hs_0027468
PH_hs_0041192
TC02000530.hg
TC02002062.hg
TC02002211.hg
TC02003380.hg
TC02003381.hg
TC02003470.hg
TC02004387.hg
TC02004507.hg
g12056970_3p_at
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
Other forms of this molecule
ANAPC1 [nucleoplasm]
Inferred To
Anapc1 [cytosol]
(Mus musculus)
Anapc1 [cytosol]
(Rattus norvegicus)
shtd [cytosol]
(Drosophila melanogaster)
APC1 [cytosol]
(Saccharomyces cerevisiae)
ANAPC1 [cytosol]
(Bos taurus)
ANAPC1 [cytosol]
(Canis familiaris)
ANAPC1 [cytosol]
(Gallus gallus)
ANAPC1 [cytosol]
(Sus scrofa)
mat-2 [cytosol]
(Caenorhabditis elegans)
anapc1 [cytosol]
(Dictyostelium discoideum)
anapc1 [cytosol]
(Xenopus tropicalis)
cut4 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_073153.1
OpenTargets
ENSG00000153107
ENSEMBL
ENSG00000153107
,
ENST00000341068
,
ENSP00000339109
HPA
ENSG00000153107-ANAPC1
GeneCards
ANAPC1
PRO
Q9H1A4
Pharos - Targets
Q9H1A4
Orphanet
ANAPC1
GlyGen
Q9H1A4
PDB
6TM5
,
5LCW
,
5A31
,
6Q6H
,
6Q6G
,
5KHU
,
4UI9
,
5L9T
,
5L9U
,
6TNT
,
8TAU
,
6TLJ
,
5LGG
,
8PKP
,
8TAR
,
5G05
,
5G04
,
9GAW
,
5KHR
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y468 L3MBTL1
1
L3MBTL1 [nucleoplasm]
(R-HSA-3222110)
0.643
3
UniProt:O60566 BUB1B
1
BUB1B [cytosol]
(R-HSA-141436)
0.643
3
UniProt:Q9Z1S0
1
BUB1B [cytosol]
(R-MMU-141436)
0.564
2
UniProt:Q9JJ66
3
Cdc20 [nucleoplasm]
(R-MMU-6783069)
Cdc20 [nucleoplasm]
(R-MMU-174112)
Cdc20 [cytosol]
(R-MMU-141412)
0.564
2
UniProt:Q13309 SKP2
3
SKP2 [nucleoplasm]
(R-HSA-975554)
PolyUb-SKP2 [nucleoplasm]
(R-HSA-9687073)
SKP2 [cytosol]
(R-HSA-975495)
0.527
3
UniProt:Q13257 MAD2L1
2
MAD2L1 [cytosol]
(R-HSA-141400)
Activated MAD2L1 [cytosol]
(R-HSA-141447)
0.527
2
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