Reactome | KLHL12 [cytosol]

KLHL12 [cytosol]

Stable Identifier

R-HSA-1504203

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q53G59 KLHL12

Gene Names

KLHL12, C3IP1

Chain

chain:1-568

Reference Genes

BioGPS Gene:59349 KLHL12

COSMIC (genes):KLHL12 KLHL12

CTD Gene:59349 KLHL12

dbSNP Gene:59349 KLHL12

ENSEMBL:ENSG00000117153 KLHL12

HGNC:19360 KLHL12

KEGG:hsa:59349 KLHL12

Monarch:59349 KLHL12

NCBI Gene:59349 KLHL12

OMIM:614522 KLHL12

UCSC:Q53G59 KLHL12

Reference Transcript

Other Identifiers

11717663_a_at

11717664_s_at

16698101

219931_3p_s_at

219931_PM_s_at

219931_s_at

225068_PM_at

225068_at

2451429

2451430

2451431

2451432

2451433

2451434

2451435

2451436

2451437

2451440

2451441

2451442

2451443

2451446

2451453

2451455

2451456

2451457

2451458

2451459

2451460

2451462

3937571

3937573

3937576

3937579

3937581

59349

65869_at

7923489

A_23_P161041

A_24_P242609

A_33_P3394021

GE62068

GO:0005515

GO:0005829

GO:0006513

GO:0006888

GO:0014029

GO:0014032

GO:0016055

GO:0016192

GO:0016567

GO:0030127

GO:0030134

GO:0030154

GO:0031410

GO:0031463

GO:0034451

GO:0042802

GO:0043226

GO:0043231

GO:0048208

GO:0048856

GO:0065003

HMNXSV003018657

HMNXSV003022245

Hs.3826.1.A2_3p_at

ILMN_1676075

ILMN_2164081

PH_hs_0000431

TC01003709.hg

g11056005_3p_a_at

g11056005_3p_s_at

Participates

as a component of

CUL3:KLHL12:RBX1 [cytosol] (Homo sapiens)

Inferred To

KLHL12 [cytosol] (Bos taurus)

KLHL12 [cytosol] (Dictyostelium discoideum)

KLHL12 [cytosol] (Gallus gallus)

Ghost homologue of KLHL12 [cytosol] (Caenorhabditis elegans)

Ghost homologue of KLHL12 [cytosol] (Canis familiaris)

Ghost homologue of KLHL12 [cytosol] (Drosophila melanogaster)

Ghost homologue of KLHL12 [cytosol] (Xenopus tropicalis)

RABIF [cytosol] (Sus scrofa)

Klhl12 [cytosol] (Mus musculus)

Klhl12 [cytosol] (Rattus norvegicus)

klhl12 [cytosol] (Danio rerio)

Cross References

ENSEMBL

ENSP00000356230, ENSG00000117153, ENST00000367261

OpenTargets

ENSG00000117153

GeneCards

KLHL12

HPA

ENSG00000117153-KLHL12

PRO

Q53G59

Pharos - Targets

Q53G59

PDB

6TTK, 6V7O, 2VPJ, 8OIO

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.795	8
UniProt:Q6IQ55 TTBK2	1	TTBK2 [cytosol] (R-HSA-5626168)	0.718	6
UniProt:O95050 INMT	1	INMT [cytosol] (R-HSA-5357693)	0.718	6
UniProt:Q9UF56 FBXL17	1	FBXL17 [nucleoplasm] (R-HSA-9708570)	0.558	11
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P41182 BCL6	1	BCL6 [nucleoplasm] (R-HSA-5223066)	0.556	3
UniProt:Q8IVS8 GLYCTK	1	GLYCTK [cytosol] (R-HSA-6799244)	0.556	3
UniProt:Q96T60 PNKP	1	PNKP [nucleoplasm] (R-HSA-5649651)	0.556	3
UniProt:O14641 DVL2	5	pp-DVL2 [cytosol] (R-HSA-3772398) p-DVL2 [cytosol] (R-HSA-201706) p-DVL2 [clathrin-coated endocytic vesicle] (R-HSA-5138444) DVL2 [cytosol] (R-HSA-201694) ub-DVL2 [cytosol] (R-HSA-4652689)	0.488	2