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TTBK2 [cytosol]
Stable Identifier
R-HSA-5626168
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Anchoring of the basal body to the plasma membrane (Homo sapiens)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
CP110 and CEP97 dissociate from the centriole (Homo sapiens)
basal body [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
MARK4 binds ODF2 in the centriole (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
Recruitment of transition zone proteins (Homo sapiens)
basal body [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
The distal appendage proteins recruit TTBK2 (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
TTBK2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6IQ55 TTBK2
Gene Names
TTBK2, KIAA0847
Chain
chain:1-1244
Reference Genes
BioGPS Gene:146057 TTBK2
COSMIC (genes):TTBK2 TTBK2
CTD Gene:146057 TTBK2
dbSNP Gene:146057 TTBK2
ENSEMBL:ENSG00000128881 TTBK2
ENSEMBL_homo_sapiens_GENE:ENSG00000128881.18 TTBK2
HGNC:19141 TTBK2
KEGG Gene (Homo sapiens):146057 TTBK2
Monarch:146057 TTBK2
NCBI Gene:146057 TTBK2
OMIM:611695 TTBK2
UCSC:Q6IQ55 TTBK2
Reference Transcript
RefSeq:NM_173500.3 TTBK2
Other Identifiers
11737742_s_at
11745419_a_at
11746222_a_at
146057
1554293_PM_at
1554293_at
1554294_PM_s_at
1554294_s_at
1554295_PM_x_at
1554295_x_at
1557073_3p_s_at
1557073_PM_s_at
1557073_s_at
16807976
213922_PM_at
213922_at
226964_PM_at
226964_at
240011_PM_at
240011_at
3435889
34899_at
3620771
3620772
3620773
3620774
3620775
3620776
3620777
3620778
3620779
3620780
3620781
3620782
3620783
3620784
3620785
3620786
3620787
3620788
3620789
3620790
3620791
3620792
3620793
3620794
3620795
3620796
3620797
3620798
3620800
3620801
3620802
3620803
3620804
3620805
3620806
3620809
3620811
3620813
3620814
3620816
3620817
3620818
3620821
3620822
3620834
3620836
3620837
3620839
3620840
3620841
3620847
3620848
3620849
3620850
3620856
3620857
3620858
3620859
3620860
3620861
3620862
55642_at
63688_at
7895165
7987928
7987960
82544_at
82545_g_at
A_23_P206169
A_24_P224342
A_24_P929268
A_33_P3215277
GE53537
GO:0000166
GO:0000226
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005814
GO:0005815
GO:0005829
GO:0005856
GO:0005929
GO:0006468
GO:0007010
GO:0007026
GO:0007165
GO:0007224
GO:0008092
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0019894
GO:0021549
GO:0021681
GO:0021935
GO:0023052
GO:0030030
GO:0030334
GO:0035869
GO:0036064
GO:0036211
GO:0042995
GO:0043226
GO:0044782
GO:0048156
GO:0048856
GO:0048870
GO:0050321
GO:0051010
GO:0060271
GO:0106310
GO:0140096
GO:1902817
GO:1904527
HMNXSV003016536
Hs.125836.1.S1_3p_at
Hs.143011.0.A1_3p_at
Hs.93552.0.A1_3p_at
Hs2.125836.2.S1_3p_at
Hs2.125836.2.S1_3p_s_at
Hs2.125836.2.S1_3p_x_at
Hs2.425116.1.S1_3p_x_at
ILMN_1653500
ILMN_1662008
ILMN_1705834
PH_hs_0026643
TC15001269.hg
TC15001270.hg
TC15002505.hg
p25930
Participates
as a component of
basal body [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
as an input of
The distal appendage proteins recruit TTBK2 (Homo sapiens)
Inferred To
TTBK2 [cytosol]
(Bos taurus)
TTBK2 [cytosol]
(Canis familiaris)
TTBK2 [cytosol]
(Gallus gallus)
TTBK2 [cytosol]
(Mus musculus)
TTBK2 [cytosol]
(Rattus norvegicus)
TTBK2 [cytosol]
(Sus scrofa)
TTBK2 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_775771.3
Guide to Pharmacology - Targets
2263
OpenTargets
ENSG00000128881
HPA
ENSG00000128881-TTBK2
GeneCards
Q6IQ55
Ensembl
ENSG00000128881
,
ENST00000567840
,
ENSP00000455734
,
ENSP00000267890
,
ENST00000267890
PRO
Q6IQ55
Pharos - Targets
Q6IQ55
Orphanet
17306
HMDB Protein
HMDBP09523
PDB
7O3B
,
7Q90
,
7Q8Y
,
7Q8Z
,
6VRF
,
6U0K
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q53G59 KLHL12
1
KLHL12 [cytosol]
(R-HSA-1504203)
0.718
6
UniProt:Q9UPV0 CEP164
1
CEP164 [cytosol]
(R-HSA-380305)
0.681
5
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