Reactome | ASPSCR1 [cytoplasmic vesicle membrane]

ASPSCR1 [cytoplasmic vesicle membrane]

Stable Identifier

R-HSA-1449582

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytoplasmic vesicle membrane

Synonyms

TUG (ASPSCR1), Tether containing UBX domain for GLUT4, ASPC1_HUMAN, ASPSCR1, TUG

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BZE9 ASPSCR1

Gene Names

ASPSCR1, ASPL, RCC17, TUG, UBXD9, UBXN9

Chain

initiator methionine:, chain:2-553

Reference Genes

BioGPS Gene:79058 ASPSCR1

COSMIC (genes):ASPSCR1 ASPSCR1

CTD Gene:79058 ASPSCR1

dbSNP Gene:79058 ASPSCR1

ENSEMBL:ENSG00000169696 ASPSCR1

HGNC:13825 ASPSCR1

KEGG:hsa:79058 ASPSCR1

Monarch:79058 ASPSCR1

NCBI Gene:79058 ASPSCR1

OMIM:606236 ASPSCR1

UCSC:Q9BZE9 ASPSCR1

Reference Transcript

Other Identifiers

11725647_a_at

11748963_x_at

16838937

218908_3p_at

218908_PM_at

218908_at

3738354

3738355

3738356

3738357

3738358

3738359

3738360

3738361

3738363

3738364

3738365

3738375

3738376

3738377

3738378

3738379

3738380

3738381

3738382

3738383

3738384

3738385

3738390

3738391

3738392

3738393

3738394

3738395

3738396

3738397

3738399

3738400

3738401

3738402

3738405

3738406

3738407

3738408

3738409

3738410

3738411

3738412

3738413

3738414

3738415

3738416

3738417

3738418

3738419

3738420

3738421

3738422

3738423

3738424

4041230

4041232

4041233

4041234

4041235

79058

8010702

91322_at

A_14_P104609

A_14_P105926

A_14_P129901

A_23_P32320

A_33_P3228573

A_33_P3264394

A_33_P3272117

A_33_P3290588

GE82792

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0006886

GO:0009898

GO:0012505

GO:0012506

GO:0016020

GO:0031401

GO:0033116

GO:0042593

GO:0043226

GO:0043231

GO:0046324

GO:0048471

HMNXSV003021292

HMNXSV003022609

HMNXSV003027552

ILMN_1661860

ILMN_1688180

PH_hs_0028144

TC17000942.hg

g13129077_3p_at

g13129077_3p_x_at

Participates

as an output of

SLC2A4 (GLUT4) vesicle fuses with the plasma membrane (Homo sapiens)

as a component of

SLC2A4:ASPSCR1 [cytoplasmic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001238817.1, NP_001317457.1, NP_076988.1

OpenTargets

ENSG00000169696

ENSEMBL

ENSP00000462329, ENST00000306739, ENSP00000302176, ENST00000306729, ENSP00000306625, ENSG00000169696, ENST00000580534

HPA

ENSG00000169696-ASPSCR1

GeneCards

ASPSCR1

PRO

Q9BZE9

Pharos - Targets

Q9BZE9

Orphanet

ASPSCR1

GlyGen

Q9BZE9

PDB

5IFW, 7OAT, 5IFS

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55072 VCP	8	VCP [cytosol] (R-HSA-1181251) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [extracellular region] (R-HSA-6806191) VCP [secretory granule lumen] (R-HSA-6801039) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [nucleoplasm] (R-HSA-5643745) VCP [endoplasmic reticulum membrane] (R-HSA-8943105) Me3K315-VCP [cytosol] (R-HSA-8932209)	0.965	36
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:Q9Y6A5 TACC3	1	TACC3 [cytosol] (R-HSA-2160956)	0.556	3
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:P49760 CLK2			0.556	3
UniProt:Q07627 KRTAP1-1	1	KRTAP1-1 [cytosol] (R-HSA-6809855)	0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.556	3
UniProt:Q96C01 F136A			0.527	4
UniProt:Q9BZV1 UBXN6			0.527	2
UniProt:Q8TBC3 SHKBP1	1	SHKBP1 [cytosol] (R-HSA-9714849)	0.527	4
UniProt:P15104 GLUL	1	GLUL [cytosol] (R-HSA-70603)	0.527	2