Reactome | HIF:CBP:p300 [nucleoplasm]

Stable Identifier

R-HSA-1234099

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
11959977	Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response De Guzman, RN, Dyson, HJ, Dames, SA, Wright, PE, Martinez-Yamout, M	Proc Natl Acad Sci U S A	2002
7836384	Purification and characterization of hypoxia-inducible factor 1 Semenza, GL, Wang, GL	J Biol Chem	1995
11959990	Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha Livingston, DM, Freedman, SJ, Sun, ZY, Eck, MJ, Wagner, G, Kung, AL, Poy, F	Proc Natl Acad Sci U S A	2002
9822602	Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha Carrero, P, O'Brien, S, Poellinger, L, Kallio, PJ, Okamoto, K, Tanaka, H, Makino, Y	EMBO J	1998
11063749	Molecular mechanism of hypoxia-inducible factor 1alpha -p300 interaction. A leucine-rich interface regulated by a single cysteine Milligan, J, Gu, J, Huang, LE	J Biol Chem	2001
10202154	Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300 Abe, H, Yodoi, J, Mimura, J, Hirota, K, Poellinger, L, Sogawa, K, Ema, M, Fujii-Kuriyama, Y	EMBO J	1999
9632793	Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein Ebert, BL, Bunn, HF	Mol Cell Biol	1998

Participants

components

Participates

as an output of

This entity regulates

Positively

Inferred To

HIF:CBP:p300 [nucleoplasm] (Canis familiaris)

HIF:CBP:p300 [nucleoplasm] (Danio rerio)

HIF:CBP:p300 [nucleoplasm] (Gallus gallus)

HIF:CBP:p300 [nucleoplasm] (Mus musculus)

HIF:CBP:p300 [nucleoplasm] (Sus scrofa)

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