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PROS25 [cytosol]
Stable Identifier
R-DME-206278
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Circadian Clock pathway (Drosophila melanogaster)
Degradation of CRY (Drosophila melanogaster)
Cytosolic CRY is degraded by the 26S proteasome (Drosophila melanogaster)
26S proteasome [cytosol] (Drosophila melanogaster)
PROS25 [cytosol] (Drosophila melanogaster)
Degradation of PER (Drosophila melanogaster)
Cytosolic PER is degraded by the 26S proteasome (Drosophila melanogaster)
26S proteasome [cytosol] (Drosophila melanogaster)
PROS25 [cytosol] (Drosophila melanogaster)
Degradation of TIM (Drosophila melanogaster)
Cytosolic TIM is degraded by the 26S proteasome (Drosophila melanogaster)
26S proteasome [cytosol] (Drosophila melanogaster)
PROS25 [cytosol] (Drosophila melanogaster)
Hedgehog pathway (Drosophila melanogaster)
N-HH ligand not bound to PTC receptor complex (Drosophila melanogaster)
Ubiquitination and proteolysis of phosphorylated CI (Drosophila melanogaster)
Ubiquitinated and phosphorylated CI is partially degraded by the proteasome complex (Drosophila melanogaster)
26S proteasome [cytosol] (Drosophila melanogaster)
PROS25 [cytosol] (Drosophila melanogaster)
Toll pathway (Drosophila melanogaster)
Degradation of NF-kappa-B inhibitor, CACT (Drosophila melanogaster)
Phosphorylated CACT is degraded in the cytosol (Drosophila melanogaster)
26S proteasome [cytosol] (Drosophila melanogaster)
PROS25 [cytosol] (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Ubiquitination and degradation of phosphorylated ARM (Drosophila melanogaster)
Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex (Drosophila melanogaster)
26S proteasome [cytosol] (Drosophila melanogaster)
PROS25 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P40301 Prosalpha2
Gene Names
Prosalpha2, PROS-25, Pros25, CG5266
Chain
chain:1-234
Reference Genes
BioGPS Gene:41531 Prosalpha2
CTD Gene:41531 Prosalpha2
KEGG:dme:Dmel_CG5266 Prosalpha2
Monarch:41531 Prosalpha2
NCBI Gene:41531 Prosalpha2
UCSC:P40301 Prosalpha2
Reference Transcript
RefSeq:NM_079604.3 Prosalpha2
Other Identifiers
153303_at
1635872_at
41531
GO:0000502
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005839
GO:0006511
GO:0019773
GO:0030163
GO:0043161
GO:0051603
Participates
as a component of
26S proteasome [cytosol] (Drosophila melanogaster)
Other forms of this molecule
PROS25 [nucleoplasm]
Prosalpha2 [secretory granule lumen]
Prosalpha2 [extracellular region]
Prosalpha2 [ficolin-1-rich granule lumen]
Prosalpha2 [nucleoplasm]
Prosalpha2 [cytosol]
Cross References
RefSeq
NP_524328.1
ENSEMBL
FBtr0082590
,
FBgn0086134
,
FBpp0082062
FlyBase
FBgn0086134
PRO
P40301
Interactors (15)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7JWV5 Q7JWV5
0.621
3
UniProt:Q9XZJ4 Prosalpha1
4
PROSalpha6 [nucleoplasm]
(R-DME-216186)
PROSalpha6 [cytosol]
(R-DME-205787)
Prosalpha1 [nucleoplasm]
(R-DME-174314)
Prosalpha1 [cytosol]
(R-DME-68734)
0.621
3
UniProt:P12881 Prosalpha6
4
PROS35 [nucleoplasm]
(R-DME-216129)
PROS35 [cytosol]
(R-DME-206188)
Prosalpha6 [nucleoplasm]
(R-DME-174333)
Prosalpha6 [cytosol]
(R-DME-68724)
0.547
2
UniProt:Q7K148
6
Prosbeta5 [cytosol]
(R-DME-9908135)
Prosbeta5 [cytosol]
(R-DME-9908126)
Prosbeta5 [cytosol]
(R-DME-9908127)
Prosbeta5 [cytosol]
(R-DME-68762)
Prosbeta5 [nucleoplasm]
(R-DME-174344)
Prosbeta5 [cytosol]
(R-DME-68753)
0.547
2
UniProt:Q9XYN7 Prosbeta3
4
PROSbeta3 [nucleoplasm]
(R-DME-216230)
PROSbeta3 [cytosol]
(R-DME-206158)
Prosbeta3 [nucleoplasm]
(R-DME-174341)
Prosbeta3 [cytosol]
(R-DME-68747)
0.547
2
UniProt:Q9VUJ1 Prosbeta2
10
PROSbeta2 [nucleoplasm]
(R-DME-216237)
PROSbeta2 [cytosol]
(R-DME-206031)
Prosbeta2 [secretory granule lumen]
(R-DME-6803279)
Prosbeta2 [extracellular region]
(R-DME-6806449)
Prosbeta2 [ficolin-1-rich granule lumen]
(R-DME-6803312)
Prosbeta2 [cytosol]
(R-DME-9908145)
Prosbeta2 [cytosol]
(R-DME-9908123-2)
Prosbeta2 [cytosol]
(R-DME-68741-2)
Prosbeta2 [nucleoplasm]
(R-DME-174331)
Prosbeta2 [cytosol]
(R-DME-68759)
0.547
2
UniProt:Q9VK14 Q9VK14
0.547
2
UniProt:Q9VJJ0 CG17331
4
CG17331 [nucleoplasm]
(R-DME-216116)
CG17331 [cytosol]
(R-DME-206285)
Prosbeta4 [nucleoplasm]
(R-DME-174335)
Prosbeta4 [cytosol]
(R-DME-68744)
0.547
4
UniProt:Q9W414
2
Rpt4 [nucleoplasm]
(R-DME-174319)
Rpt4 [cytosol]
(R-DME-68783)
0.547
2
UniProt:P18053
2
Prosalpha3 [nucleoplasm]
(R-DME-174324)
Prosalpha3 [cytosol]
(R-DME-68730)
0.547
4
UniProt:Q95083 Prosalpha5
7
PROSMA5 [nucleoplasm]
(R-DME-216225)
PROSMA5 [cytosol]
(R-DME-205764)
Prosalpha5 [secretory granule lumen]
(R-DME-6803316)
Prosalpha5 [extracellular region]
(R-DME-6806459)
Prosalpha5 [ficolin-1-rich granule lumen]
(R-DME-6803328)
Prosalpha5 [nucleoplasm]
(R-DME-174340)
Prosalpha5 [cytosol]
(R-DME-68732)
0.547
2
UniProt:P48601 Rpt2
4
PROS26.4 [nucleoplasm]
(R-DME-216113)
PROS26.4 [cytosol]
(R-DME-206110)
PSMC1 [nucleoplasm]
(R-DME-174338)
PSMC1 [cytosol]
(R-DME-68768)
0.547
2
UniProt:Q9VNA5 Prosbeta7
5
CG12000 [nucleoplasm]
(R-DME-216212)
CG12000 [cytosol]
(R-DME-205917)
Prosbeta7 [cytosol]
(R-DME-9908138)
Prosbeta7 [nucleoplasm]
(R-DME-174343)
Prosbeta7 [cytosol]
(R-DME-68750)
0.547
3
UniProt:O18413 Rpt6
4
PROS45 [nucleoplasm]
(R-DME-216274)
PROS45 [cytosol]
(R-DME-206026)
PSMC5 [nucleoplasm]
(R-DME-174312)
PSMC5 [cytosol]
(R-DME-68780)
0.547
3
UniProt:Q9V5C6 Prosalpha7
4
PROSalpha7 [nucleoplasm]
(R-DME-216210)
PROSalpha7 [cytosol]
(R-DME-205958)
Prosalpha7 [nucleoplasm]
(R-DME-174323)
Prosalpha7 [cytosol]
(R-DME-68728)
0.547
2
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