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phospho-p-T185,Y187-MAPK1 [cytosol]
Stable Identifier
R-DME-109853
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
P40417
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Prophase (Drosophila melanogaster)
Golgi Cisternae Pericentriolar Stack Reorganization (Drosophila melanogaster)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Drosophila melanogaster)
p-Y204-MAPK3-3/p-T185,Y187-MAPK1 homodimer [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to heat stress (Drosophila melanogaster)
Regulation of HSF1-mediated heat shock response (Drosophila melanogaster)
Constitutive phosphorylation by pERK1/2 (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
L1CAM interactions (Drosophila melanogaster)
Recycling pathway of L1 (Drosophila melanogaster)
Phosphorylation of L1 by ERK (Drosophila melanogaster)
pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signal transduction by L1 (Drosophila melanogaster)
MAP2K2 phosphorylates MAPK1 (Drosophila melanogaster)
p-S,T-MAP2K2:p-T,Y-MAPK1 [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by NODAL (Drosophila melanogaster)
The SMAD2/3:SMAD4 complex transfers to the nucleus (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Drosophila melanogaster)
The SMAD2/3:SMAD4 complex transfers to the nucleus (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Thrombin signalling through proteinase activated receptors (PARs) (Drosophila melanogaster)
Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Drosophila melanogaster)
F2R:ARRB1:active MAPKs:active SRC-1 [plasma membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Interferon Signaling (Drosophila melanogaster)
Interferon gamma signaling (Drosophila melanogaster)
JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Regulation of actin dynamics for phagocytic cup formation (Drosophila melanogaster)
p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Programmed Cell Death (Drosophila melanogaster)
Apoptosis (Drosophila melanogaster)
Intrinsic Pathway for Apoptosis (Drosophila melanogaster)
Apoptotic factor-mediated response (Drosophila melanogaster)
Cytochrome c-mediated apoptotic response (Drosophila melanogaster)
Formation of apoptosome (Drosophila melanogaster)
Regulation of the apoptosome activity (Drosophila melanogaster)
CASP9 is phosphorylated at T412 (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF-independent MAPK1/3 activation (Drosophila melanogaster)
Cytosolic DUSPs dephosphorylate MAPKs (Drosophila melanogaster)
p-T,Y MAPK monomers and dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
MAPK1 (ERK2) activation (Drosophila melanogaster)
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Drosophila melanogaster)
p-S,T-MAP2K2:p-T,Y-MAPK1 [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
MAP2K2 phosphorylates MAPK1 (Drosophila melanogaster)
p-S,T-MAP2K2:p-T,Y-MAPK1 [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Phosphorylated MAPKs translocate into the nucleus (Drosophila melanogaster)
p-T,Y MAPK monomers and dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs dimerize (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Drosophila melanogaster)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Drosophila melanogaster)
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
Cytosolic DUSPs dephosphorylate MAPKs (Drosophila melanogaster)
p-T,Y MAPK monomers and dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Negative feedback regulation of MAPK pathway (Drosophila melanogaster)
Activated MAPK phosphorylates RAF1 (Drosophila melanogaster)
p-T,Y MAPK monomers and dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Activated MAPKs phosphorylate BRAF (Drosophila melanogaster)
p-T,Y MAPK monomers and dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Activated MAPKs phosphorylate MAP2K1 (Drosophila melanogaster)
p-T,Y MAPK monomers and dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
PTPN7 binds p-T,Y-MAPK (Drosophila melanogaster)
PTPN7:p-T,Y-MAPK dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
PTPN7 dephosphorylates p-T,Y-MAPKs (Drosophila melanogaster)
PTPN7:p-T,Y-MAPK dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Phosphorylated MAPKs translocate into the nucleus (Drosophila melanogaster)
p-T,Y MAPK monomers and dimers [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs dimerize (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
Estrogen-stimulated signaling through PRKCZ (Drosophila melanogaster)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR1 (Drosophila melanogaster)
Negative regulation of FGFR1 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is serine phosphorylated in response to MAPK activation (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by FGFR2 (Drosophila melanogaster)
Negative regulation of FGFR2 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is serine phosphorylated in response to MAPK activation (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by FGFR3 (Drosophila melanogaster)
Negative regulation of FGFR3 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is serine phosphorylated in response to MAPK activation (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by FGFR4 (Drosophila melanogaster)
Negative regulation of FGFR4 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is serine phosphorylated in response to MAPK activation (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by NTRKs (Drosophila melanogaster)
Signaling by NTRK1 (TRKA) (Drosophila melanogaster)
Signalling to ERKs (Drosophila melanogaster)
Prolonged ERK activation events (Drosophila melanogaster)
Frs2-mediated activation (Drosophila melanogaster)
Dissociation of phosphorylated MAP2Ks and MAPKs (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPK dimers translocate to nucleus (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs dimerize (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate WASPs and WAVEs (Drosophila melanogaster)
p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by Activin (Drosophila melanogaster)
The SMAD2/3:SMAD4 complex transfers to the nucleus (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Drosophila melanogaster)
The SMAD2/3:SMAD4 complex transfers to the nucleus (Drosophila melanogaster)
p-T,Y MAPK dimers [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
phospho-p-T185,Y187-MAPK1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P40417
Reference Genes
BioGPS Gene:3354888
CTD Gene:3354888
ENSEMBL:FBgn0003256
Flybase:FBgn0003256
KEGG Gene (Drosophila melanogaster):Dmel_CG12559
Monarch:3354888
NCBI Gene:3354888
Reference Transcript
RefSeq:NM_001110879.2
RefSeq:NM_001015121.3
RefSeq:NM_001110878.4
RefSeq:NM_001015123.3
RefSeq:NM_001015122.3
RefSeq:NM_001300706.2
Other Identifiers
1629549_s_at
3354888
GO:0000165
GO:0000166
GO:0000278
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006468
GO:0006914
GO:0007049
GO:0007166
GO:0007173
GO:0007362
GO:0007430
GO:0007465
GO:0007474
GO:0007476
GO:0007479
GO:0007552
GO:0008284
GO:0008286
GO:0008293
GO:0008340
GO:0008543
GO:0009267
GO:0009605
GO:0016242
GO:0016301
GO:0016310
GO:0016740
GO:0019901
GO:0022414
GO:0023052
GO:0030154
GO:0031594
GO:0033554
GO:0034614
GO:0035169
GO:0035170
GO:0035202
GO:0035556
GO:0036211
GO:0042060
GO:0043226
GO:0045500
GO:0045793
GO:0046534
GO:0046843
GO:0048010
GO:0048149
GO:0048856
GO:0050804
GO:0051091
GO:0051607
GO:0060446
GO:0070371
GO:0071243
GO:0071276
GO:0090303
GO:0098542
GO:0106310
GO:0140096
GO:0140297
GO:2000826
GO:2001023
Participates
as an input of
Phosphorylation of L1 by ERK (Drosophila melanogaster)
as a component of
pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome] (Drosophila melanogaster)
p-S,T-MAP2K2:p-T,Y-MAPK1 [cytosol] (Drosophila melanogaster)
p-T185,Y187 MAPK1 dimer [cytosol] (Drosophila melanogaster)
as an output of
Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Drosophila melanogaster)
as a member of
p-T,Y MAPKs [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
phospho-p-T202,Y204-MAPK3 [nucleoplasm]
phospho-p-T202,Y204-MAPK3 [cytosol]
MAPK1 [cytosol]
MAPK3 [cytosol]
MAPK3 [nucleoplasm]
MAPK1 [nucleoplasm]
phospho-p-T185-MAPK1 [cytosol]
phospho-p-T202-MAPK3 [cytosol]
phospho-p-Y204-MAPK3-3 [cytosol]
MAPK1 [ficolin-1-rich granule lumen]
MAPK1 [extracellular region]
MAPK1 [azurophil granule lumen]
Inferred From
p-T185,Y187-MAPK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 185 (in Homo sapiens)
Coordinate
185
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O4'-phospho-L-tyrosine at 187 (in Homo sapiens)
Coordinate
187
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_001104348.2
,
NP_001015122.1
,
NP_001104349.1
,
NP_001015121.3
,
NP_001015123.1
,
NP_001287635.1
Flybase
FBgn0003256
IntEnz
2.7.11.24
PRO
P40417
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9U1H0 CIC
0.593
3
UniProt:Q24106 HID
0.59
3
UniProt:Q9V393 krz
8
krz [cytoplasmic vesicle membrane]
(R-DME-351187-3)
krz [Golgi membrane]
(R-DME-350831-3)
krz [lysosomal membrane]
(R-DME-432701-3)
krz [cytosol]
(R-DME-6783000)
krz [cytosol]
(R-DME-6783186-3)
Krz [cytosol]
(R-DME-2071841)
krz [cytosol]
(R-DME-416464)
krz [cytosol]
(R-DME-264470-3)
0.544
12
UniProt:Q24324 Dsor1
9
DSOR1 [cytosol]
(R-DME-205968)
phospho-p-S,218, S222,T292 MAP2K1 [cytosol]
(R-DME-5674490)
phospho-p-S,T-MAP2K2 [cytosol]
(R-DME-109848)
phospho-p-T286,T292-MAP2K1 [cytosol]
(R-DME-112374)
phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol]
(R-DME-112339)
MAP2K1 [cytosol]
(R-DME-59502)
MAP2K2 [cytosol]
(R-DME-59504)
phospho-p-S222,S226-MAP2K2 [cytosol]
(R-DME-169292)
phospho-p-S218,S222-MAP2K1 [cytosol]
(R-DME-109837)
0.534
2
UniProt:Q24496 Q24496
0.524
2
UniProt:Q9W2K3 Q9W2K3
0.488
2
UniProt:P21461
2
SIAH2 [cytosol]
(R-DME-374566)
SIAH1 [cytosol]
(R-DME-374563)
0.488
2
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