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phospho-p-T286,T292-MAP2K1 [cytosol]
Stable Identifier
R-DME-112374
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q24324
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
L1CAM interactions (Drosophila melanogaster)
Signal transduction by L1 (Drosophila melanogaster)
MAP2K1 phosphorylates MAPK3 (Drosophila melanogaster)
p-2T-MAP2K1 [cytosol] (Drosophila melanogaster)
phospho-p-T286,T292-MAP2K1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF-independent MAPK1/3 activation (Drosophila melanogaster)
MAPK3 (ERK1) activation (Drosophila melanogaster)
Inactivation of MAP2K1 by CDK1 (Drosophila melanogaster)
p-2T-MAP2K1 [cytosol] (Drosophila melanogaster)
phospho-p-T286,T292-MAP2K1 [cytosol] (Drosophila melanogaster)
MAP2K1 phosphorylates MAPK3 (Drosophila melanogaster)
p-2T-MAP2K1 [cytosol] (Drosophila melanogaster)
phospho-p-T286,T292-MAP2K1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q24324 Dsor1
Gene Names
Dsor1, CG15793
Chain
chain:1-396
Reference Genes
BioGPS Gene:31872 Dsor1
KEGG Gene (Drosophila melanogaster):Dmel_CG15793 Dsor1
Monarch:31872 Dsor1
NCBI Gene:31872 Dsor1
Reference Transcript
RefSeq:NM_078543.4 Dsor1
RefSeq:NM_001298115.1 Dsor1
Other Identifiers
154939_at
1626006_at
31872
GO:0000165
GO:0000166
GO:0000278
GO:0000793
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004708
GO:0004713
GO:0005515
GO:0005524
GO:0005634
GO:0005635
GO:0005694
GO:0005829
GO:0006468
GO:0007095
GO:0007173
GO:0007298
GO:0007362
GO:0007430
GO:0007465
GO:0008286
GO:0008293
GO:0008340
GO:0008543
GO:0009953
GO:0016301
GO:0016310
GO:0016740
GO:0019900
GO:0022414
GO:0023052
GO:0030154
GO:0033314
GO:0036211
GO:0042386
GO:0042461
GO:0043226
GO:0045500
GO:0048010
GO:0048856
GO:0048870
GO:0051607
GO:0070371
GO:0071481
GO:0098542
GO:0106310
GO:0140096
Participates
as a member of
p-2T-MAP2K1 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
DSOR1 [cytosol]
phospho-p-S,218, S222,T292 MAP2K1 [cytosol]
phospho-p-S,T-MAP2K2 [cytosol]
phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol]
MAP2K1 [cytosol]
MAP2K2 [cytosol]
phospho-p-S222,S226-MAP2K2 [cytosol]
phospho-p-S218,S222-MAP2K1 [cytosol]
Inferred From
p-T286,T292-MAP2K1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 286 (in Homo sapiens)
Coordinate
286
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 292 (in Homo sapiens)
Coordinate
292
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001285044.1
,
NP_511098.1
Flybase
FBgn0010269
PRO
Q24324
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11346 Raf
20
Phospho PHL [plasma membrane]
(R-DME-205859)
PHL [cytosol]
(R-DME-205713)
phospho-p-S338,Y340,Y341-RAF1 [cytosol]
(R-DME-5624465)
phospho-p-S338-RAF1 [cytosol]
(R-DME-5624469)
BRAF [cytosol]
(R-DME-167224)
phospho-hyperphosphorylated BRAF [plasma membrane]
(R-DME-5675199)
phospho-hyperphosphorylated RAF1 [plasma membrane]
(R-DME-5675193)
phospho-p-S299,S302,T452,T455,S582 ARAF [cytosol]
(R-DME-5672646)
phospho-p-S446,T599,S602,S729 BRAF [cytosol]
(R-DME-5672676)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-DME-5672664)
phospho-p-S446,S729-BRAF [cytosol]
(R-DME-5672673)
phospho-p-S446,T599,S602,S729 BRAF [plasma membrane]
(R-DME-5672679)
phospho-p-S299,S302,T452,T455,S582 ARAF [plasma membrane]
(R-DME-5672648)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-DME-5672665)
phospho-p-S582 ARAF [cytosol]
(R-DME-5672681)
phospho-p-S621-RAF1 [cytosol]
(R-DME-206028)
RAF1 [cytosol]
(R-DME-167205)
phospho-p-S214,S582 ARAF [cytosol]
(R-DME-5672639)
phospho-p-S259,S621-RAF1 [cytosol]
(R-DME-109786)
phospho-p-S365,S446,S729 BRAF [cytosol]
(R-DME-5672667)
0.667
5
UniProt:P40417
14
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
(R-DME-112354)
phospho-p-T202,Y204-MAPK3 [nucleoplasm]
(R-DME-112359)
phospho-p-T202,Y204-MAPK3 [cytosol]
(R-DME-109842)
phospho-p-T185,Y187-MAPK1 [cytosol]
(R-DME-109853)
MAPK1 [cytosol]
(R-DME-59282)
MAPK3 [cytosol]
(R-DME-59284)
MAPK3 [nucleoplasm]
(R-DME-73724)
MAPK1 [nucleoplasm]
(R-DME-199960)
phospho-p-T185-MAPK1 [cytosol]
(R-DME-9635773)
phospho-p-T202-MAPK3 [cytosol]
(R-DME-9635775)
phospho-p-Y204-MAPK3-3 [cytosol]
(R-DME-2422448)
MAPK1 [ficolin-1-rich granule lumen]
(R-DME-6800964)
MAPK1 [extracellular region]
(R-DME-6806250)
MAPK1 [azurophil granule lumen]
(R-DME-6799225)
0.534
2
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